Coupled Endothelial and Smooth Muscle Cell Model

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Description

This computational model simulates shear-induced NO signalling in endothelial (EC) and smooth muscle cells (SMC) to study arterial behaviour. The SMC model includes actin-myosin cycling, intracellular Ca²⁺, and NO signalling, while the EC model captures shear stress-induced NO production. Coupling these models predicts SMC contraction under varying shear stress. Implemented in CellML, the model provides insights into arterial function and vascular regulation.

Owner

Fariba Bahadori <fbir042@aucklanduni.ac.nz>

URI for git clone/pull/push

https://models.physiomeproject.org/workspace/c88

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