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Challenge
Accelerators > Our Accelerators > Challenge
The solutions of the future won't build themselves.
Our Challenge programs match rare founders with corporate powerhouses to move discovery into practice, turning early validation into real-world adoption.
Challenge
Programs
We know that progress in systems-critical markets requires collaboration across startups, industry, government, and philanthropy. Yet today that work is full of friction and failure points. Our Challenge programs are built for that reality, purpose-designed to reduce friction in co-innovation by accelerating co-discovery, matchmaking, co-validation, and ultimately, co-commercial outcomes.
Outcomes
PILOTS
Where ideas meet real conditions. Founders test solutions alongside industry leaders to prove feasibility and fit.
PROOFS OF CONCEPT
Early validation that turns potential into proof. Together, founders and partners test what works and why it matters.
COMMERCIAL OUTCOMES
When collaboration becomes traction. Breakthroughs move from pilot to market with partners ready to scale.
Upcoming Programs
Interested in upcoming programs in the United States?
Complete this form to be notified when new programs are announced.
Looking for programs outside the US?
Use the regional links below to explore current and upcoming programs in our global hubs.
For questions about our programs, contact our team directly at programs@masschallenge.org.
Now Accepting Applications
Open Program
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Open Program
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Open Program
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Founder stories and alumni spotlights coming soon!
Featuring real-world outcomes, pilots, partnerships, and breakthroughs from the global MassChallenge network.
Real Voices. Real Impact.
MassChallenge has been incredible for us. It’s hard to be an entrepreneur, especially in climate, and the programming helped us see that we’re not the only ones in this. One of the main learnings I’ve gotten from this program is that impact and profitability are not mutually exclusive.
DAVID GORY
Founder and CEO at Airbuild
I wouldn’t just say this was something that I needed professionally, but on a personal level too. It’s about you as a person first. The people at MassChallenge and this community made me feel confident stepping into healthcare in a way I wasn’t before.
KYLE HENRY
CEO and Co-Founder, Tune Health
MassChallenge has been an incredible opportunity for us. It’s rare for a startup at our stage to work directly with enterprise partners. Through the program, we’ve been able to engage with enterprise users early on, understand their pain points, and build better solutions. Over the past few months, we’ve taken our product from prototype to production-ready, and without MassChallenge, this progress wouldn’t have been possible.
SHUAI LI
2x Founder
It takes a community to raise a startup. You can be deep in technology, but you need the network, the right advisors, and the right connections. That’s what MassChallenge brought, and it made something complex feel executable.
RICK WHITTAKER
CEO and CoFounder of AirShare
I am so excited for the networking we’ve gone through. Together it takes all of us to make the world a better place. If you’re looking for the networking and the connections and the people that will help you take your company to the next level, this is one of the most worthwhile programs.
JIM BOYTE
Founder & CEO at ActiveDefender
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