Startups Accelerated
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Follow-on Capital Raised
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Direct Jobs Created
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We back the rare humans with the grit to solve the toughest challenges.
Accelerating solutions in Healthcare & Life Sciences, Security & Resiliency, Sustainable Food Systems, Climate, and Global Financial Systems.
We back the rare humans with the grit to solve the toughest challenges.
Accelerating solutions in Healthcare & Life Sciences, Security & Resiliency, Sustainable Food Systems, Climate, and Global Financial Systems.
Different by Design
Since 2009, we’ve built a formidable global network and we’re obsessive about giving founders breakthrough access to the people and power that move markets. Corporates, customers, regulators, funders—leaders who understand complexity and help you scale what truly matters.
FOUNDERS
Founders need more than capital. They need access, insight, and relationships that unlock momentum. We accelerate those connections through proven programs, giving you the leverage to move faster and go further.
EXPERTS
Our experts—founders, operators, researchers, and industry leaders—support you at critical inflection points, Their real-world insight sharpens your roadmap: technical, go-to-market, or team. Every connection delivers high-impact access when it matters most.
COLLABORATORS
Our collaborators know progress demands more than optimism. Together, we work to reshape the systems founders rely on, whether capital, policy, and industry, especially where barriers are steepest. We ensure founders have the support they need to reach scale.
Real words from the founders redefining what's possible.
MassChallenge has been incredible for us. It’s hard to be an entrepreneur, especially in climate, and the programming helped us see that we’re not the only ones in this. One of the main learnings I’ve gotten from this program is that impact and profitability are not mutually exclusive.
DAVID GORY
Founder and CEO at Airbuild
I wouldn’t just say this was something that I needed professionally, but on a personal level too. It’s about you as a person first. The people at MassChallenge and this community made me feel confident stepping into healthcare in a way I wasn’t before.
KYLE HENRY
CEO and Co-Founder, Tune Health
MassChallenge has been an incredible opportunity for us. It’s rare for a startup at our stage to work directly with enterprise partners. Through the program, we’ve been able to engage with enterprise users early on, understand their pain points, and build better solutions. Over the past few months, we’ve taken our product from prototype to production-ready, and without MassChallenge, this progress wouldn’t have been possible.
SHUAI LI
2x Founder
It takes a community to raise a startup. You can be deep in technology, but you need the network, the right advisors, and the right connections. That’s what MassChallenge brought, and it made something complex feel executable.
RICK WHITTAKER
CEO and CoFounder of AirShare
I am so excited for the networking we’ve gone through. Together it takes all of us to make the world a better place. If you’re looking for the networking and the connections and the people that will help you take your company to the next level, this is one of the most worthwhile programs.
JIM BOYTE
Founder & CEO at ActiveDefender
Featured Partners
Apply to a Program
Please check back for upcoming programming.
Let us know you are interested by filling out this form to be notified when new programs are announced.
For questions about our programs, contact programs@masschallenge.org.