Silditop 100 mg works by blocking the PDE5 enzyme, which normally breaks down cyclic guanosine monophosphate (cGMP). When cGMP levels remain higher, the smooth muscles in the penile blood vessels relax, allowing improved blood circulation during sexual arousal. However, sexual stimulation is still required for the medicine to work effectively. This dose is commonly used as a standard therapeutic strength for many men with erectile dysfunction. It is usually taken about 30 to 60 minutes before sexual activity, and its effects typically last for around 4 to 6 hours, depending on individual factors such as age, health condition, and metabolism. https://www.genericday.com/silditop-100-mg.html