It's not possible to reconfigure host endpoint datapath options because it has reserved labels and we disable it in the API:

$ cilium endpoint config 2644 Debug=Enabled
Error: Cannot update endpoint 2644: [PATCH /endpoint/{id}/config][400] patchEndpointIdConfigInvalid 

This by itself is fine, but in PR #11977 we disable datapath debug mode by default, which means we can't turn it back on.

Combined with the RuntimeMonitor tests which iterate through all endpoints to make sure that debug mode outputs events for all endpoints, this causes a test failure.