Scientific Program

9:00 (9:00 am) Make a Difference: Global Angioedema Leadership Conference joint welcome

• Speakers: Anthony J Castaldo (HAEi), Henrik Balle Boysen (HAEi), Markus Magerl (ACARE)

9:25 (9:25 am) Move to the Global Angioedema Leadership Conference scientific room

9:30 (9:30 am) Welcome, introduction, and objectives

• Speaker: Markus Magerl (Germany)

Chairs: Mar Guilarte (Spain), Stefan Cimbollek (Spain)

9:40 (9:40 am) Angioedema: How did we get there? 

• Speaker: Bruce Zuraw (USA)

9:50 (9:50 am) Angioedema: Bradykinin and where the science could take us

• Speaker: Alvin Schmaier (USA)

Chairs: Mar Guilarte (Spain), Stefan Cimbollek (Spain)

10:00 (10:00 am) Angioedema diagnosis

• Speaker: Laurence Bouillet (France)

10:15 (10:15 am) Roundtable: Differential diagnosis in recurrent angioedema – what are the problems and the solutions?

• Panel: Anete Grumach (Brazil), Ankur Jindal (India), Philip Li (Hong Kong), Stephen Betschel (Canada), Petra Staubach-Renz (Germany)
• Facilitator: Mar Guilarte (Spain)

10:40 (10:40 am) Oral Presentation: Investigation of early complement components and C1INH values in newborns with positive family history of HAE-C1INH

• Speaker: Lili Voloncs-Mindszenthy (Hungary)

10:50 (10:50 am) Oral Presentation: Suspicion of hereditary angioedema with normal C1 inhibitor – Insights into clinical characteristics and outcomes of genetic testing from the first global ACARE project

• Speaker: Kathrin Schön (Germany)

11:00 (11:00 am) Oral Presentation: Inheritance patterns of hereditary angioedema due to C1 inhibitor deficiency in 72 families

• Speaker: Hanga Réka Horváth (Hungary)

11:10 (11:10 am) Coffee break, exhibits and networking

Chair: Ankur Jindal (India)

11:35 (11:35 am) Living with a recurrent angioedema – the patient view

• Speakers: Rachel Annals (HAEi, United Kingdom), Yong Hao Lim (HAE Singapore)
• Facilitator: Deborah Corcoran (HAEi, United Kingdom)

11:45 (11:45 am) Interactive Patient Journey

• Speakers: Thomas Buttgereit (Germany), Kathrin Schön (Germany)
• Panel: Connie Katelaris (Australia), Ricardo Zwiener (Argentina), Teresa Caballero (Spain), Daria Fomina (Russia), Priya Bowry (Kenya)

12:30 (12:30 pm) Industry session

12:40 (12:40 pm) Lunch break, exhibits, and networking

13:00 (1:00 pm) ACARE drop-in sessions (optional: 2 available)

1. How to become an ACARE/UCARE
2. How to participate in the CARE registry

The ACARE team invites you to visit their exhibition area to discuss the topics in more detail and answer any questions you may have.

Chairs: Yuxiang Zhi (China), Markus Magerl (Germany)

14:00 (2:00 pm) Burden, comorbidities and predictors of attacks in recurrent angioedema – the physician view

• Speaker: Connie Katelaris (Australia)

14:20 (2:20 pm) Oral Presentation: Highlighting the wider psychosocial impact of hereditary angioedema (HAE) beyond physical attacks: findings from 4 multi-national patient experience surveys

• Speaker: Kathrin Schön (Germany)

14:30 (2:30 pm) Oral Presentation: Suicidal ideation among patients with hereditary angioedema: early results from the SAFE-HAE BRADILAT initiative

• Speaker: Carolina Crespo-Shijin (Ecuador)

14:40 (2:40 pm) Oral Presentation: Characteristics and burden of caregivers of patients with hereditary angioedema: Results from the ECRINS study

• Speaker: Isabelle Boccon-Gibod (France)

14:50 (2:50 pm) Hot topic: HAE with normal C1-INH

• Speaker: Sandra Christiansen (USA)

15:15 (3:15 pm) Industry session

15:25 (3:25 pm) Coffee break, exhibits, and networking

Chairs: Danny Cohn (Netherlands), Connie Katelaris (Australia)

15:50 (3:50 pm) Real-life experience: Managing HAE and advocating to making a difference

• Speakers: Priya Bowry (Kenya), Philip Li (Hong Kong)
• Facilitator: Danny Cohn (Netherlands)
• Panel: Ankur Jindal (India), Solange Olivera Valle (Brazil), Rachel Annals (HAEi, United Kingdom), Stefan Cimbollek (Spain), Henriette Farkas (Hungary), Andrea Zanichelli (Italy), Jugurtha Rami (Algeria)

16:30 (4:30 pm) Oral Presentation: TBC

• Speaker: TBC

16:40 (4:40 pm) Oral Presentation: Real-world evidence on healthcare resource utilization in patients treated with lanadelumab: Learnings from the French National SNDS database

• Speaker: Laurence Bouillet (France)

16:50 (4:50 pm) Oral Presentation: Canadian physicians’ use of long-term prophylaxis for hereditary angioedema in a pediatric population

• Speaker: Natasha Correa (Canada)

17:00 (5:00 pm) Angioedema Jeopardy: Test your knowledge

• Speaker: Marc Riedl (USA)
• Panel: Luis Felipe Ensina (Brazil), Thomas Buttgereit (Germany), Sandra Christiansen (USA), Isabelle Boccon-Gibod (France), Philip Li (Hong Kong), Priya Bowry (Kenya)

18:00 (6:00 pm) Closing remarks

• Speakers: Ankur Jindal (India), Henriette Farkas (Hungary), Anete Grumach (Brazil)

18:05 (6:05 pm) Move to the scientific poster room

18:10 (6:10 pm) Poster session including structured time with selected short talks, and unstructured time

• Chairs for structured time: Teresa Caballero (Spain), Mar Guilarte (Spain), Stefan Cimbollek (Spain)

Click here for the abstract list, which includes details of oral and poster presentations, and poster numbers.

07:00 (7:00 am) Registration

8:30 (8:30 am) Welcome to day 2, summary of day 1

• Speakers: Ankur Jindal (India), Henriette Farkas (Hungary), Anete Grumach (Brazil)

Chair: Mar Guilarte (Spain)

8:40 (8:40 am) Roundtable: Managing angioedema in special populations

• Facilitator: Bruce Zuraw (USA)
• Panel: Mauro Cancian (Italy), Henriette Farkas (Hungary), Sandra Christiansen (USA),  Daria Fomina (Russia), Isabelle Boccon-Gibod (France), Teresa Caballero (Spain), Hassen Messaoudi (Algeria)

9:20 (9:20 am) Oral Presentation: One-time lonvoguran ziclumeran (lonvo-z) 50mg in patients with hereditary angioedema: Up to 3 years durability and safety update

• Speaker: Padmalal Gurugama (United Kingdom)

9:30 (9:30 am) Oral Presentation: Impact of navenibart on HAE attack rates and health-related quality of life: Results from the ALPHA-STAR trial

• Speaker: Anna Valerieva (Bulgaria)

9:40 (9:40 am) Oral Presentation: Results of the phase 2 CHAPTER-1 open-label extension study on the long-term safety and efficacy of oral deucrictibant for prophylaxis in hereditary angioedema

• Speaker: Emel Aygören-Pürsün (Germany)

9:50 (9:50 am) Move to workshop room

9:55 (9:55 am) Workshops

(1) Genetic testing and variants in angioedema

Chair: Ankur Jindal (India)

• Speakers: Matija Rijavec (Slovenia), Ágnes Szilágyi (Hungary), Anastasios Germenis (Greece)

(2) Family screening

Chair: Anete Grumach (Brazil)

• Speakers: Oscar Calderon Llosa (Peru), Isabelle Boccon-Gibod (France)

10:25 (10:25 am) Coffee break, exhibits, and networking

10:50 (10:50 pm) Industry session

Chairs: Stefan Cimbollek (Spain), Philip Li (Hong Kong)

11:00 (11:00 am) This House believes in the DANCE classification

• Present the case, including questions. Speaker: Avner Reshef (Israel)

11:20 (11:20 am) This House believes that anabolic androgens still have a role to play in the treatment of HAE

• Present the case, including questions. Speaker: Bruce Zuraw (USA)

Chairs: Philip Li (Hong Kong), Stefan Cimbollek (Spain)

11:40 (11:40 am) Oral Presentation: Sustained and clinically meaningful improvements in quality of life during treatment with navenibart: Interim results from the ALPHA-SOLAR trial

• Speaker: Raffi Tachdjian (USA)

11:50 (11:50 am) Oral Presentation: On-demand oral sebetralstat for hereditary angioedema attacks in children aged 2-11: interim analysis of KONFIDENT-KID

• Speaker: Emel Aygören-Pürsün (Germany)

Chairs: Stefan Cimbollek (Spain), Philip Li (Hong Kong)

12:00 (12:00 pm) Angioedema tools: what we have and what’s missing

• Speaker: Teresa Caballero (Spain)
• Facilitator: Markus Magerl (Germany)
• Panel: Ivan Cherrez (Ecuador), Marcin Stobiecki (Poland), Danny Cohn (Netherlands), Luis Felipe Ensina (Brazil), Maryam Ali Al-Nesf (Qatar), Priya Bowry (Kenya)

12:25 (12:25 pm) New ACAREs and news from ACARE

• Speaker: Markus Magerl (Germany)

12:40 (12:40 pm) Key ACARE projects

• Speaker: Thomas Buttgereit (Germany)

12:50 (12:50 pm) Introducing “Excellence on Demand”

• Speaker: Reinhardt Britz (ACARE)

13:05 (1:05 pm) Close of main scientific program

Speaker: Markus Magerl (Germany)

13:10 (1:10 pm) Lunch break, exhibits, and networking

13:30 (1:30 pm) Drop-in sessions (optional: 2 available)

1. How to become an ACARE/UCARE
2. How to participate in the CARE registry

The ACARE team invites you to visit their exhibition area to discuss the topics in more detail and answer any questions you may have.

• ACARE – best practices with Member Organizations, physicians, and virtual angioedema centers
• Real lives, real challenges: What makes a difference?
• HAEi Global Angioedema Leadership Conference – key highlights from the tracks

15:35 (3:35 am) Coffee break, exhibits, and networking

16:10 (4:10 pm) Make a difference – partnering for progress – part 2

• HAEi LEAP and HAEi Youngsters Advisory Group
• HAEi’s patient-driven research and targeted research

• Speakers: Anthony J Castaldo (HAEi), Henrik Balle Boysen (HAEi), Markus Magerl (ACARE)