Ukwandiswa kweSifo esiNgapheliyo esiThintelayo sePulmonary (COPD) kukwehla kweempawu okanye ukugqabhuka okunokuba neziphumo ezibalulekileyo zexesha elifutshane nezexesha elide. Kuyabonakala ukuba izigulane ezingaphantsi kwengxelo exacerbation zinokuba neziphumo ezibi ezifanayo njengabo baxelayo kwaye kunokubakho amaxesha angama-2-5 angaphezulu angabonakaliyo kunokuba achazwe.
I-COPD Exacerbation Recognition Tool (CERT) eyaphuhliswayo kwaye iphethwe yi-GSK, yenzelwe abantu abaneCOPD ukuba baqaphele ukuqala kokunyuka kunye nokuqonda isidingo sokuxela oko kubaboneleli babo bezempilo.
I-CERT ibonelela ngesikhokelo esibonakalayo esilula kwizigulana ukubanceda baqaphele iimpawu zabo kwaye bafune unyango xa lufuneka. Injongo kukwenza lula ulawulo lweCOPD kunye nokuphucula umgangatho wobomi kubantu abaphethwe yiCOPD.
I-CERT yaphuhliswa e-China ziingcali kunye nabaphandi abasebenza ngokubambisana nezigulane, ngenkxaso evela kwi-GSK. Yenziwa kwimimandla eyahlukeneyo e-China, ibandakanya amaqela ahlukeneyo abantu abafunyaniswa bene-COPD kwaye baye bafumana ukwanda kwixesha elidlulileyo.
- Inkqubo yophuhliso ibandakanya abathathi-nxaxheba abakuluhlu olubanzi lobudala, kunye namanqanaba ahlukeneyo emfundo nokufunda, kubandakanywa nabo bangakwaziyo ukufunda nokubhala.
- Ngethuba lophuhliso lwayo, olubandakanya udliwano-ndlebe lwezigulane, abaphandi banciphisa i-CERT phantsi kwezinto ezi-5 ezahlukeneyo ezinxulumene nokuqala kokunyuka:
- Ukhohlokhohlo oluya luqatsela
- Ukwanda kwemveliso yesikhohlela
- Ukuqhawukelwa ngumphefumlo
- Ukunciphisa intshukumo
- Injongo ye-CERT kukuba izigulane ziqaphele ukuba ukuba iimpawu zabo ziba nzima ngendlela echazwe ngayo, banokuthi bafumane ukuqala kokunyuka.
- Inika izigulane ukuqonda okungcono malunga nokubaluleka kotshintsho lwamva nje kwiimpawu zabo.
- Inkalo ephambili licebiso lokufuna unyango ukuba umguli wehlelwa yilo tshintsho.
- Uvavanyo lwento ethile kunye novakalelo lwe-CERT luyaqhubeka, kunye nomsebenzi wokuqinisekisa i-CERT kumazwe ahlukeneyo.
- Abaphandi bakholelwa ukuba i-CERT inokunceda abantu abaphila ne-COPD bazi xa kufuneka baxelele ababoneleli babo bezempilo malunga nokuvela kokugqithisa, ukwenzela ukuba unyango lwabo lunokulungiswa, ukuba kuyimfuneko.
- I-CERT ayisosixhobo sokuxilonga ukonyuka kweCOPD.
- Isetyenziselwa nje ukunceda izigulana zichonge iimpawu ezibonisa ukuqala kokunyuka, ukuze bazi xa kufuneka bafune unyango.
- Izigulana kufuneka zilandele isikhokelo se-CERT, kodwa ukuba ziba mandundu ngokukhawuleza ngeendlela ezingachazwanga kwi-CERT, kufuneka zicetyiswe ukuba ziqhubeke zifuna unyango.
I-CERT isimahla ukuba isetyenziswe ngoogqirha kunye nezigulana.
I-CERT ikhuselwe yi-copyright.
"Iimpawu zorhwebo zezenkampani okanye zinikwe ilayisenisi kwiqela le-GSK leenkampani. © 2023 Iqela le-GSK leenkampani okanye umniki-layisensi."
Naluphi na utshintsho okanye iinguqulelo ze-CERT zifuna imvume yiBhodi yoLawulo ye-CERT.
I-GAAPP iqalise ukusebenzisana malunga nokuhlanganiswa kwemibuzo ye-CERT ekwidijithali kunye nenguqulelo yesiJamani ye-CERT User Guide for Providers kwiqonga lolwazi lwezigulane olusetyenziswa ngesiJamani eliqhutywa yiHelmholtz Munich (LID): www.lungeniinforificationsdienst.de
Inguqulelo yedijithali ye-CERT ngoku ikwi-intanethi ene-LID yezigulane eJamani: https://www.lungeninformationsdienst.de/service/selbsttests/cert-copd-exazerbationserkennungstool
Isifundo saseJamani esenziwe ngu UGqr. Rainer Gloeckl, Phd Ilungu le-CERT GB elikhutshwe kwiphepha lasekhaya le-LID nakwi-YouTube: https://www.youtube.com/watch?v=8hpsIhzO9yI
Ividiyo yepodcast enesihloko esithi “Pneumo4Coffee2Go” malunga ne-CERT erekhodwe yiGerman Respiratory Society: https://www.youtube.com/watch?v=lKodHPgRQeo&t=1658s
Ividiyo yokufundisa yoogqirha eyenziwe yi-GSK ngenjongo yokwenza kube lula ukuyisebenzisa ekliniki njengesixhobo sokufundisa izigulane: https://youtu.be/Wb0WBwrbKz0
Ukubukela ividiyo malunga nezifundo ezenziwe eTshayina, skena le khowudi ye-QR ngefowuni yakho okanye ucofe Apha
I-CERT yePoskhadi yeMfundo yokuKhuphela
Khuphela iSikhokelo soMsebenzisi we-CERT apha:
I-CERT yaseJapan (i-CERT-J) ineenjongo ezifanayo njenge-CERT yokuqala. Yaphuhliswa ngokwahlukileyo kwi-CERT, kodwa umxholo wayo ufana kakhulu [11]. Umahluko ophambili yinto eyongezelelweyo equkiweyo ekulandeleni iingcebiso zeengcali zaseJapan. Omnye umahluko kukuba i-CERT-J icebisa ukuba izigulana zifune unyango xa izinto ezintathu okanye ngaphezulu zisiba mandundu. Kuzo zonke ezinye iinkalo kufuneka isetyenziswe ngendlela efanayo ne-CERT.
I-CERT ijolise ekusetyenzisweni njengenxalenye yenkqubo yemfundo apho izigulane zeCOPD zifunda ukuguqulwa okubalulekileyo kwendlela yokuphila njengoku: ukuyeka ukutshaya, ukutya kunye nomsebenzi womzimba / utshintsho lokuzivocavoca, ukuqonda ukubaluleka kwezitofu zokugonya, kunye nesidingo sokuthobela unyango olucetyiswayo kunye nokunakekelwa kwezonyango.
Ezinye izixhobo ezimbini kufuneka zikhankanywe
- UVavanyo loVavanyo lweeNqwelo zomoya eziNgapheliyo (I-CAAT) ukulinganisa iimpawu zeCOPD kunye nefuthe lazo kwimpilo yesigulane kunye nempilo. Inokulandelela utshintsho kwisimo sempilo yesigulana ekuhambeni kwexesha kwaye isebenze njengendlela yokunxibelelana phakathi kwezigulane kunye noogqirha. [7] Ayenzelwanga ukuqaphela ukuqala kokugqithisa.
- The EXACT® kunye ne-E-RS Ziidayari zemihla ngemihla zihlala zisetyenziswa kulingo lwezonyango ukulandelela iimpawu zeCOPD kunye nokuchonga izifo eziya ziba mandundu. Kubalulekile ukuqonda ukuba i-CERT ayisiyodayari yemihla ngemihla ukuba isetyenziswe ngolu hlobo.
IBhodi yoLawulo ye-CERT (GB)
Injongo yethu kukwenza i-CERT ifumaneke kubaphulaphuli behlabathi bezigulana, iintsapho, kunye nababoneleli bezempilo. IGlobal Allergy and Airways Patient Platform (GAAPP), i-amburela yehlabathi jikelele engenzi nzuzo equka imibutho ethethelela izigulana ezininzi, ithathe ukhokelo lokusebenza lwe-GB ngoJulayi 2024 ngemvume evela ku-GSK, umnini welungelo lokushicilela.
I-GB iya kugxininisa ekuqinisekiseni i-CERT yesayensi yengqibelelo kunye nesicwangciso sophuhliso ngelixa isebenza kunye neqela lamazwe ngamazwe leSayensi kunye neClinikhi yeengcali ezigxile ekuqinisekiseni, ekusasazeni, ekuguquleleni nasekuphunyezweni kwe-CERT kwiinkcubeko ezahlukeneyo.
Amalungu eBhodi yoLawulo ye-CERT
- UGqr Ruth Tal-Singer, PhD, uSihlalo wokuSebenza kweBhodi
IGosa leSayensi eliyiNtloko
I-GAAPP, eVienna, eOstriya - UNjingalwazi uPaul Jones, uSihlalo weSiseko kunye noMphuhlisi weCERT
Ugqirha oPhando oluPhezulu weGAAPP (uMcebisi)
UNjingalwazi oHloniphekileyo, iSixeko saseSt George's, kwiYunivesithi yaseLondon - UMandeep Moore GphC, uMkhokheli weShishini, GSK, UK
- Unjingalwazi uToru Oga, uMsebenzisi woPhando lwezeMfundo eAsia Pacific
ISebe leMiyeza yokuphefumla, iSikolo sezoNyango saseKawasaki
eKurashiki, eOkayama, eJapan - UGqr. Rainer Gloeckl, Phd
Iziko loPhando lokuBuyiselwa kwemiphunga,
Schön Klinik Berchtesgadener Land, Schönau am Königssee, eJamani - Nandita Dandekar
Umseki kunye noMlawuli, iSiseko soMthi oPinki,
Impilo yoMthi oPinki, eMumbai, eIndiya.
Ucaphulo
- Jones PW, Lamarca R, Chuecos F, et al. Ubume kunye nefuthe lokwenyuka kwengxelo kunye nokungaxelwanga: iziphumo ezivela kwi-ATTAIN. I-Eur Respir J. 2014;44(5):1156–1165. doi: 10.1183/09031936.00038814
- Wilkinson TM, Donaldson GC, Hurst JR, Seemungal TA, Wedzicha JA. Unyango lwakwangoko luphucula iziphumo zokunyanzeliswa kwezifo ezingapheliyo zemiphunga. Ndingu-J Respir Crit Care Med. 2004;169(12):1298–1303. doi: 10.1164 / rccm.200310-1443OC
- ULeidy NK, uMurray LT, uJones P, uSethi S. Ukwenziwa kwe-EXAcerbations yesifo se-pulmonary esingapheliyo isixhobo esichazwe ngesigulane kwizilingo ezintathu zeklinikhi zesifo esingapheliyo se-pulmonary. UAnn Am Thorac Soc. 2014;11(3):316–325. doi: 10.1513/AnnalsATS.201309-305OC
- Betsuyaku T, Kato M, Fujimoto K, et al. Ulingo olungenamkhethe lolawulo olusekwe kwiimpawu kwizigulana zaseJapan ezineCOPD. Int J Chron Obstruct Pulmon Dis. 2018;13:2409-2423. doi: 10.2147/COPD.S152723
- I-Langsetmo L, i-Platt RW, i-Ernst P, i-Bourbeau J. I-Underreporting exacerbation of chronic obstructive pulmonary disease in a longitudinal cohort. Ndingu-J Respir Crit Care Med. 2008;177(4):396–401. doi:
- UJones PW, Wang C, Chen P, Chen L, Wang D, Xia J, Yang Y, Wang Y, Ma Q. Uphuhliso lweSixhobo sokuQatshelwa kweCOPD exacerbation (CERT) ukuNcedisa izigulane ukuba zibone ixesha lokufuna iNgcebiso yezoNyango. Int J Chron Obstruct Pulmon Dis. 2022 Jan 21; 17:213-222. doi: 10.2147/COPD.S337644. PMID: 35087270; I-PMCID: PMC8789323.
- Mackay AJ, Donaldson GC, Patel AR, et al. Ukusebenziseka kovavanyo lovavanyo lwesifo semiphunga esingapheliyo ukuvavanya ubukhali beCOPD exacerbations. Ndingu-J Respir Crit Care Med. 2012;185(11):1218–1224. doi: 10.1164 / rccm.201110-1843OC.
- Jones PW, Chen WH, Wilcox TK, et al. Ukulinganisa kunye nokulinganisa iimpawu ze-COPD exacerbations. Isifuba. 2011;139(6):1388–1394. doi: 10.1378/chest.10-1240.
- ULeidy NK, uWilcox TK, uJones PW, et al. Ukuphuhliswa kwe-EXAcerbations ye-Chronic Obstructive Pulmonary Disease Tool (EXACT): umlinganiselo wesiphumo esichazwe ngesigulane (PRO). Ixabiso leMpilo. 2010;13(8):965–975. doi: 10.1111/j.1524-4733.2010.00772.x.
- ULeidy NK, uWilcox TK, uJones PW, et al. Ukulinganisa umlinganiselo wezifo ezingapheliyo ze-pulmonary exacerbations. Ukuthembeka kunye nokunyaniseka kwedayari echazwe ngesigulane. Am J Respir Crit Care M ed. 2011;183(3):323–329. doi: 10.1164 / rccm.201005-0762OC.
- Jones, uPawulos et al. "Uphuhliso lweSixhobo soNxibelelwano phakathi kwezigulane kunye nooGqirha ukuze baqaphele ukuKhutshwa kweCOPD eJapan." COPD ivol. 20,1 (2023): 216-223. ikhonkco: 10.1080 / 15412555.2023.2219742
- Xing, Xiangju et al. "Ukuqinisekiswa kunye noHlalutyo oluPhambili lwe-COPD yeSixhobo sokuQinisekisa ngokuQinisayo (CERT)." I-Respirology (Carton, Vic.), 10.1002/resp.70159. 19 Nov. 2025, doi:10.1002/resp.70159
- Wang, Hao et al. "Ukuya kuQoqosho oluNgcono lwe-COPD eQinisayo kunye neZixhobo zokuNika iNgxelo eziPhakathi kwesigulana." I-Respirology (Carton, Vic.), 10.1002 / resp.70173. 25 Nov. 2025, doi:10.1002/resp.70173
- Gloeckl, uRainer et al. "Ngaba iMfundo yeMonde inokukhokelela kwindlela? Ukuthelekiswa kweNtloko-kwintloko ye-EXACT kunye ne-CERT yokuQatshelwa kwangethuba lokuQiniswa kwe-COPD eAcute." I-Respirology (Carton, Vic.), 10.1002/resp.70170. 30 Nov. 2025, doi:10.1002/resp.70170
- UGloeckl R, uTal-Singer R, uDeussen P, et al. Isixhobo sokuqaphela ukugqithiswa kwe-COPD: ukuqinisekiswa koguqulelo, ulwimi, kunye neenkcubeko ezahlukeneyo. Ezingapheliyo Obstr Pulm Dis. 2026; 13(2): 147-157. doi: http://doi.org/10.15326/jcopdf.2025.0745
Inkxaso-mali ibonelelwa yi-AstraZeneca, iSanofi, iGSK, iBoehringer Ingelheim