F3 Tech Biomanufacturing Facility

A Hub for Biotech Innovation on Maryland’s Eastern Shore

Our 6,000 sq. ft. pilot-scale biomanufacturing facility in Easton, Maryland is designed to bridge the gap between research and commercialization. With ISO 8 cleanroom labs, analytical testing capabilities, and pilot-scale equipment, we provide the infrastructure innovators need to validate processes, accelerate product development, and prepare for market entry.

F3 Facility Instrumentation Overview

Our Goal: Accelerate Early-Stage Innovation

The F3 facility is designed to provide a turnkey environment for concept validation, formulation refinement, and prototype development. Startups can rapidly test hypotheses, generate high-quality data, and de-risk future manufacturing or regulatory steps- all within a single, fully equipped space. Whether your goal is to verify a new biological mode of action, optimize a fermentation process, or establish reproducible analytical profiles, the F3 infrastructure accelerates your path from idea to validated innovation.

Together, the following systems aim to provide a practical platform for early bioprocess development, strain optimization, and formulation testing- key steps before investing in large-scale production.

Analytical & Biophysical Systems

Shimadzu Nexera X2 HPLC
Enables precise separation and quantification of compounds in complex mixtures, ideal for purity assessment, metabolite profiling, and formulation consistency checks.
Shimadzu LCMS-8050 Triple Quadrupole Mass Spectrometer
Provides detailed molecular characterization essential for defining chemical fingerprints, confirming target molecules, and screening production batches.
Nicoya OpenSPR
Offers real-time biophysical data on molecular interactions, helping early innovators verify mechanisms of action, binding affinity, or protein–ligand behavior without large sample volumes.
Agilent Microplate Reader
Supports rapid bioassay screening, enabling quantitative detection of biological activity or growth responses, key for hit validation and formulation optimization.

Microbial & Molecular Biology Equipment

Thermo Scientific Herasafe KS Class II Biosafety Cabinet
Provides a sterile, contained workspace for safe microbial and molecular manipulations, supporting regulatory and quality standards.
Bio-Rad CFX-96 Real-Time PCR System
Enables gene-level quantification and expression profiling, valuable for validating strain performance or confirming mode-of-action hypotheses.

Fermentation & Bioprocess Systems

Bioprocess control systems are aimed to bridge lab discovery and pilot-scale production. Key equipment include:

Two Eppendorf BioFlo 120 Benchtop Bioreactors
Deliver automated, precision-controlled fermentation under customizable pH, dissolved oxygen, and temperature conditions. These systems help optimize growth, improve yields, and generate reproducible data for scale-up feasibility- critical for startups transitioning toward biomanufacturing.
Thermo Scientific Forma Orbital Shaker
Complements the bioreactors by supporting parallel culture experiments under controlled agitation and temperature, ideal for screening media formulations or assessing growth kinetics.

Current Capabilities

Pilot-Scale Bioreactors

Access enterprise-grade bioreactors for process development, validation, and scale-up. Our pilot systems help startups bridge the gap between lab research and commercialization, without the cost of building proprietary infrastructure.

Analytical Testing Lab

Refine processes and validate products with fully equipped testing capabilities. Our labs support quality control and optimization, helping companies accelerate regulatory readiness and market entry.

ISO 8 Lab Spaces

Dedicated cleanroom environments designed for bioprocessing and product testing. Flexible layouts allow startups to adapt space to their unique workflows and scale efficiently.

Business Support Services

Receive tailored business guidance, mentorship, and commercialization planning. Our team helps navigate regulatory, financial, and operational hurdles to speed your path to market.

Workforce Training

Hands-on education and training programs prepare the next generation of biotech workers. We provide pipeline development for students and upskilling opportunities for incumbent employees.

Applications & Use Cases

Our facility supports companies working across human health, agriculture, aquaculture, and industrial biotechnology. Example applications include:

Human Health: monoclonal antibodies, vaccines, insulin, gene & cell therapy, cultured meat.
Agriculture & Aquaculture: biofeed and food additives, sustainable farming solutions, aquaculture technologies.
Industrial & Environmental: biofuels, bioplastics, enzymes, secondary metabolites.

Why It Matters

By providing access to pilot-scale infrastructure, F3 Tech is creating the foundation for a second Bio Corridor in Maryland. This facility will:

Accelerate commercialization of biologics and agricultural biotech.
Support federal initiatives for domestic supply chain security.
Provide training and career pathways for Maryland’s biotech workforce.
Attract national and global innovators to the Eastern Shore.