The McMaster Textbook of Internal Medicine is the first Canadian textbook of internal medicine developed at McMaster University, the birthplace of problem-based learning (PBL) and evidence-based medicine (EBM). It uses GRADE criteria to assess the quality of evidence.

McMaster Perspective

The McMaster Perspective interview series is a collection of in-depth conversations that brings together the world’s leading medical experts and McMaster University’s renowned evidence-based medicine (EBM) approach. These interviews feature distinguished physicians and researchers discussing the latest developments and enduring challenges in medicine—all delivered in an engaging conversational format that makes complex topics accessible and memorable.

Roman Jaeschke and Mark Loeb
Video
Mark Loeb, MD, MSc, professor of pathology and molecular medicine at McMaster University and Canada...
Timothy M. Niessen and Brian T. Garibaldi
Video
Brian T. Garibaldi, MD, and Timothy M. Niessen, MD, reflect on the current role of bedside medicine...
Hertzel C. Gerstein
Video
Hertzel C. Gerstein, MD, endocrinologist and professor at McMaster University and Hamilton Health...

Browse all videos

Browse the McMaster Perspective video archive.

Calculators

A collection of easy-to-use clinical calculators to help quickly estimate key health metrics.

BMI calculator

Calculate the body mass index (BMI) or determine the target weight for a given BMI.

Blood glucose converter

Convert blood glucose between mg/dL and mmol/L.

FAQ

Questions about the McMaster Textbook

What happened with the McMaster Textbook? How do I transfer my existing subscription to the new site? What is ebm.one? Click here for answers to the most commonly asked questions.

McMaster Selects Journal Club

The McMaster Selects Journal Club features critical reviews of carefully selected recent publications identified by McMaster University editors as most likely to impact clinical practice. Each review examines studies that may lead to practice-changing recommendations or otherwise influence the daily practice of medicine.

McMaster Selects
Article
Background Tirzepatide is a dual glucose-dependent insulinotropic polypeptide (GIP) receptor and...
McMaster Selects
Article
Background In hospitalized patients who require intravenous fluid supplementation there is...
McMaster Selects
Article
Background Broad- and extended-spectrum antibiotics are routinely used instead of standard-spectrum...

Browse all reviews

Browse the McMaster Selects review collection.

Evidence-based medicine in a nutshell

All you need to know about EBM: A founder’s guide to evidence, guidelines & getting back to the core

What was medicine like before evidence-based medicine (EBM)? Gordon Guyatt, MD, the pioneer who coined the term EBM, reveals how a revolutionary movement transformed clinical practice from reliance on expert opinion and intuition to systematic evaluation of research evidence. Dr Guyatt candidly discusses both the triumphs and limitations of the EBM’s evolution while emphasizing a crucial insight that challenges the “cookbook medicine” critique: most clinical decisions require personalized shared decision-making between doctors and patients, because evidence alone cannot account for individual values and preferences.

Open access lectures

Prof Serena Gundy (McMaster University, Canada)
Video
Lecture by Prof Serena Gundy (McMaster University, Canada). Recorded at the 10th edition of the...
Mark Loeb
Video
Lecture by Prof Mark Loeb (McMaster University, Canada). Recorded at the 10th edition of the...
Video
Lecture by Prof Vijay Kunadian (Newcastle University, UK). Recorded at the 9th edition of the...
Video
Lecture by Dr Timothy M. Niessen (Johns Hopkins University School of Medicine, USA). Recorded at...

Rapid Refreshers

Internal Medicine Rapid Refreshers is a series of concise information-packed videos refreshing your knowledge on key medical issues that general practitioners may encounter in their daily practice.

Simon Oczkowski
Video
Internal Medicine Rapid Refreshers is a series of concise information-packed videos refreshing...
Bram Rochwerg
Video
Internal Medicine Rapid Refreshers is a series of concise information-packed videos refreshing...

Watch all videos

Browse the Rapid Refreshers.

Evidence-based medicine basics

A set of full-length lectures discussing the fundamentals of evidence-based medicine. Recorded at 2017 conference Evidence-Based Medicine and Clinical Practice Guidelines in Contemporary Practice.

Gordon Guyatt
Video
Lecture by Dr Gordon Guyatt from McMaster University, Canada. Recorded at Evidence-Based Medicine...
Victor Montori
Video
Lecture by Dr Victor Montori from Mayo Clinic, Rochester, Minnesota, USA. Recorded at Evidence-...
Waleed Alhazzani
Video
Lecture by Dr Waleed Alhazzani from King Saud University, Riyadh, Saudi Arabia. Recorded at...

Watch all lectures

Browse the complete set of lectures from Evidence-Based Medicine and Clinical Practice Guidelines in Contemporary Practice.

Video case reports

Young Talents in Internal Medicine World Contest is an international competition developed for young internists interested in research and illustrating the problem-based learning approach using real-life scenarios.

Dr Peter Todd, Scotland
Video
1st place winner presentation by Dr Peter Todd, Scotland. Recorded at Young Talents in Internal...
Dr Radwa Genidy, United Arab Emirates
Video
3rd place winner presentation by Dr Radwa Genidy, United Arab Emirates. Recorded at Young Talents...

Browse case presentations from the Young Talents in Internal Medicine World Contest

The Young Talents in Internal Medicine World Contest is an international competition developed for young internists interested in research and illustrating the problem-based learning approach using real-life scenarios.

About the McMaster Textbook

About the McMaster Textbook

The McMaster Textbook of Internal Medicine is the first Canadian textbook of internal medicine developed at McMaster University, the birthplace of problem-based learning (PBL) and evidence-based medicine (EBM) and one of the leading medical schools in the world. Covering the essential fields of internal medicine, the textbook is aimed at answering the needs of medical professionals and trainees who seek access to updated, verified medical knowledge useful in everyday practice.

Free chapters

Browse selected chapters from the McMaster Textbook of Internal Medicine completely free—no subscription required.

Chapter
Definition, Etiology, PathogenesisTop Infective endocarditis (IE) is an infection of the...
Chapter
There are 4 main areas of auscultation: Figure 1.18-1Figure 1.18-1Figure 031_9939. Areas of...
Chapter
The perioperative management of patients who are receiving a direct oral anticoagulant (DOAC) and...
Chapter
Definition, etiology, pathogenesisTop Cardiac arrest refers to cessation of cardiac mechanical...

Premium content: MIRCIM video collection

The McMaster International Review Conference of Internal Medicine (MIRCIM) is an annual international medical conference organized in collaboration with McMaster University, known for pioneering evidence-based medicine. It focuses on clinical reasoning, case-based learning, and updates in internal medicine from leading experts worldwide.

MIRCIM 2025

10th edition of the McMaster International Review Conference of Internal Medicine

MIRCIM 2024

9th edition of the McMaster International Review Course in Internal Medicine

A decade of medical excellence

Browse the MIRCIM video collection (2015-2025).

Open access

McMaster Selects
Article
Background Although transient ischemic attacks (TIAs) and minor strokes are common cerebrovascular...
Chapter
Definition, Etiology, PathogenesisTop Infective endocarditis (IE) is an infection of the...
Hertzel C. Gerstein
Video
Hertzel C. Gerstein, MD, endocrinologist and professor at McMaster University and Hamilton Health...
Ashkan Shoamanesh
Video
Ashkan Shoamanesh, MD, associate professor of medicine at McMaster University who holds the Marta...

Search

Explore

Contents

Loading...