About Us

Senior Management

Arun Swaminathan, Ph.D.

Chief Executive Officer

Fred Grossman, D.O., FAPA

President & Chief Medical Officer

David Snyder, M.B.A.

Chief Financial Officer & Chief Operating Officer

Michelle Frazier, Ph.D.

Senior VP of Regulatory

Aaron Thome, Ph.D.

Head of Neuroinflammation Platform

Karen King, MS

Senior VP of Program Management & Clinical Operations

Daniel Barvin, M.B.A.

Vice President of Operations & Patient Advocacy

Dan Jordan, M.B.A.

Senior Director, Manufacturing & Technical Operations

Tyrell Simkins, D.O., Ph.D.

Senior Director, Clinical Development

Board of Directors

Mark Pavao, M.B.A.

Managing Director, Biotech Value Advisors

Wilbur Ross

Former U.S. Secretary of Commerce

Dieter Weinand

Anabella Villalobos, Ph.D.

Biopharmaceutical Executive – Former Biogen, Pfizer

Ann Lee, Ph.D.

Chief Technical Officer at Prime Medicine

Dov Goldstein, M.D., M.B.A.

Chief Financial Officer at BioAge

Arun Swaminathan, Ph.D.

Chief Executive Officer

Scientific Advisory Board

Shimon Sakaguchi M.D., Ph.D.

Member of the National Academy of Sciences

Clive Svendsen, Ph.D.

Director of the Cedars-Sinai Regenerative Medicine Institute

Malcolm Brenner, M.D., Ph.D.

Director of the Center for Cell and Gene Therapy and Professor at Baylor College of Medicine

Stanley Appel, M.D.

Peggy and Gary Edwards Distinguished Endowed Chair for the Treatment and Research of ALS, Co-Director of the Houston Methodist Neurological Institute

Arun Swaminathan, Ph.D.

Chief Executive Officer

Arun Swaminathan, Ph.D., has over 20 years of hands-on healthcare business executive experience with an emphasis on corporate and business development, strategy, and finance. He possesses a
demonstrated history of prospecting, evaluating, structuring, and closing company validating
transactions that augment both organizational and shareholder value.

Prior to joining Coya, Arun served as Chief Business Officer (CBO) for Actinium Pharmaceuticals (NYSE: ATNM) where he was responsible for all business development. Within 1 year of joining Actinium, he successfully moved forward negotiations to closure and executed a $452M deal with $35M upfront. Prior to Actinium, he was the CBO at Alteogen (196170.KQ) where he spearheaded over $6B in deals, including deals with two of the top 10 global pharma companies and a $1B+ deal within the first year of assuming the role of CBO. Prior to this, he co-founded and served as CEO of Lynkogen Inc, a pre-clinical stage biotech.

Arun began his career in clinical development and commercial roles of increasing responsibility at
BristolMyers Squibb and Covance. He obtained his Ph.D. in pharmaceutical sciences from the University of Pittsburgh.

Fred Grossman, D.O., FAPA

President and Chief Medical Officer

Dr. Grossman brings over 20 years of drug development expertise having held senior executive leadership positions in large and small pharmaceutical companies leading the development and FDA approval of numerous multi-billion dollar blockbuster drugs addressing significant unmet medical needs particularly across CNS disorders. He has close relationships with thought leaders worldwide and has negotiated directly with the FDA and Global Health Authorities for approval of many drugs across therapeutic areas. Dr. Grossman held executive positions at Eli Lilly, Johnson & Johnson, Bristol Myers Squibb, and Sunovion. He served as President and Chief Medical Officer at Glenmark Pharmaceuticals (BSE; 532296), a $1.5 Billion per annum global pharmaceutical company based in India, overseeing development of the entire pipeline including generics, complex generics including 505(b)(2) candidates, and next-generation biologics (including bi-specific antibodies). He also previously served as Chief Medical Officer at Mesoblast, Inc. (NASDAQ: MESO), developing allogeneic cellular therapies for inflammatory diseases. Dr. Grossman is Board-Certified in Psychiatry and a Fellow of the American Psychiatric Association and was a Fellow at the National Institutes of Health (NIH). He has held several academic appointments and authored numerous scientific publications

David Snyder

Chief Financial Officer and Chief Operating Officer

David S. Snyder brings to Coya Therapeutics over 25 years’ experience as the CFO of public and high growth companies. Prior to joining Coya, Mr. Snyder served as the CFO of DisperSol Technologies, LLC and its wholly owned subsidiary Austhera BioSciences, Inc. DisperSol and Austhera are currently advancing two late-stage, small molecule drugs through the clinic and are using their proprietary KinetiSol platform to build a pipeline of NCEs. Prior to joining DisperSol/Austhera, from 2014-2020 Snyder was the CFO of Exicure, Inc. (Nasdaq: XCUR) a company developing nucleic acid therapeutics. From 2008 to 2014, he was the CFO of Cellular Dynamics, Inc. (Nasdaq: ICEL) a company developing ipsc-based stem cell tools and primary cell therapeutics. From 2007-2008, Mr. Snyder served as Senior Vice President of Finance, Site Vice President and Chief Financial Officer of Roche NimbleGen. Prior to 2007, Snyder was CFO of companies in real estate, software, and manufacturing. Early in his career Mr. Snyder worked for financial and real estate investor Sam Zell. He received his BA summa cum laude from Ottawa University and his M.B.A. with high honors from the Harvard Business School, where he was designated a George Fisher Baker Scholar.

Michelle Frazier, Ph.D.

Senior VP of Regulatory

Dr. Frazier brings over 20 years of strong regulatory expertise since her tenure at the FDA followed by a successful career in the pharmaceutical industry. She spent 7 years at the FDA, where she was a team lead reviewing over 60 new molecular entities, overseeing multiple biologic license applications, including the first anti-angiogenic monoclonal antibody approved for cancer therapy. In turn, she was recognized multiple times for her leadership and excellence. Subsequent to FDA, she demonstrated a proven track record for overseeing and guiding successful global regulatory strategies at prestigious bio pharmaceutical companies for numerous biologic drug products leading to FDA approval of multiple biologic license applications and supplements, including Udenyca® (pegfilgrastim-cbqv biosimilar), and Blincyto®, the first bispecific monoclonal antibody product. As part of her career, Dr. Frazier has also provided strategic advice to multiple biotechnology companies. Dr. Frazier received a B.S in Microbiology from Washington State University and a Ph.D. In Cell Biology from Loyola University.

Aaron Thome, Ph.D.

Head of Neuroinflammation Platform

Aaron joins Coya to lead its Neuroinflammation Program and is responsible for developing and testing novel therapeutics that target inflammatory mechanisms which lead to disease pathogenesis. Aaron retains his position as Assistant Research Professor in the Department of Neurology at the Houston Methodist Neurological Institute, Johnson Center for Cellular Therapeutics, working closely with Dr. Stanley Appel (Coya Scientific Advisory Board), who is renowned for his discovery of Tregs as a treatment for inflammation in neurodegenerative diseases. Aaron’s transformational work includes elucidating neuroinflammatory mechanisms of neurodegenerative disease (ALS, Alzheimer’s, Parkinson’s, etc.) and developing therapeutic approaches to modulate or halt the progression of these devastating diseases. He completed his postdoctoral training with Dr. Appel at the Houston Methodist Neurological Institute, having received his Ph.D. from the University of Alabama at Birmingham at the Center for Neurodegeneration and Experimental Therapeutics. Aaron received his B.S. in Biomedical Science from Texas A&M University.

Karen King, MS

Senior VP of Program Management and Clinical Operations

Karen brings a wealth of knowledge and expertise to Coya with over 25 years of experience in the biopharmaceutical industry, specializing in clinical trials for rare and neurodegenerative diseases. As the head of Program Management and Clinical Operations, Karen will play a significant role in driving the clinical development of potentially transformative therapies in ALS, FTD, and other neurodegenerative
diseases. She is passionate about finding cures for rare diseases and improving clinical outcomes for patients and their families. Her dedication extends to her volunteer work with the nonprofit Genetic ALS and FTD: End the Legacy, further demonstrating her commitment to advancing treatments and cures for these challenging conditions.

Karen holds a master’s degree in biotechnology from Northwestern University and has a strong background in research project management, clinical development, and team leadership. Her previous roles include Vice President of Clinical Operations at Recursion, where she led the design and execution of a rare disease portfolio, and Chief Operating Officer at the Institute for Advanced Clinical Trials for Children, where she maximized clinical program operations efficiency and expanded the company significantly.

Daniel Barvin, M.B.A.

VP of Operations and Patient Advocacy

Daniel Barvin joined Coya Therapeutics in 2021, helping to launch the company alongside founder Howard Berman. As Vice President of Operations and Patient Advocacy, Daniel focuses on advancing new treatments for neurodegenerative diseases and ensuring patients receive meaningful support throughout their care.

Motivated by personal experience, Daniel co-founded Genetic ALS and FTD: End the Legacy, a non-profit dedicated to supporting individuals affected by or at risk of genetic ALS and FTD. The organization provides resources to help ease the burden on patients and families facing these challenges.

Daniel holds an MBA from Rice University and a B.S. in Mechanical Engineering from Case Western Reserve University.

Dan Jordan, M.B.A.

Senior Director, Manufacturing and Technical Operations
Dan is a seasoned pharmaceutical operations executive with over 30 years of progressive leadership across global manufacturing, engineering, and quality functions. His career spans world-class organizations such as Allogene Therapeutics, Shire, Genentech, Merck, and Boehringer Ingelheim, where he has delivered critical contributions to site start-ups, external manufacturing, technology transfer, validation, compliance remediation, and new product introduction.
With deep expertise in biologics, aseptic processing, validation, and complex supply chain management, Dan has led major greenfield projects and global cross-functional teams through transformational initiatives. Dan has extensive experience working with CDMO’s to execute technology transfer and delivery of clinical/commercial products while maintaining positive relationships. His strategic insight, strong CMC knowledge, and hands-on operational leadership style have consistently driven business results and most importantly medicines to patients.
Dan holds an MBA from Lehigh University and a BS in Electrical Engineering Technology from Penn State University. His international experience includes expat assignments in Ireland and the UK, where he successfully delivered key pipeline projects.

Tyrell Simkins, D.O., Ph.D.

Senior Director, Clinical Development
Tyrell Simkins, D.O., Ph.D., is a physician‑scientist with a strong focus on translating scientific discovery into therapies that meaningfully benefit patients. He brings extensive experience across clinical neurology and biomedical research, providing a rigorous, clinically grounded perspective to therapeutic development. Dr. Simkins is an APBN board‑certified neurologist with fellowship training in Multiple Sclerosis and Neuroimmunology, and his work centers on advancing innovative approaches to diseases of the nervous and immune systems. He is deeply committed to improving patient outcomes through thoughtful clinical strategy, scientific excellence, and collaborative drug development within the biopharmaceutical industry.

Mark Pavao, M.B.A.

Managing Director, Biotech Value Advisors
Mark Pavao has been a director since April 2026. He is a Co-Founder of Biotech Value Advisors, a commercialization strategy advisory firm serving emerging biotechnology companies and has been Managing Partner with the firm since June 2018. Earlier in his career he held multiple senior leadership roles at Bristol-Myers Squibb (NYSE: BMY), including President of the U.S. Diabetes business within the AstraZeneca / Bristol-Myers Squibb alliance from November 2012 to October 2013, where he led the creation of a stand-alone commercial organization responsible for more than $1 billion in annual revenue and over 2,000 employees. He also served as Senior Vice President of the Cardiovascular & Metabolics business unit from April 2012 to October 2012, President of Emerging Markets from April 2010 to April 2012, Senior Vice President of Global Market Access & Pricing from June 2008 to April 2012, and Senior Vice President of the U.S. Neuroscience business unit from April 2007 to June 2008. Mr. Pavao currently serves as Chair of the Board of Medical Knowledge Group and has been a board member of Perosphere Technologies since January 2024. He also serves on the board of MiracleFeet, a global nonprofit organization dedicated to eliminating untreated clubfoot in low- and middle-income countries, where he previously served as Board Chair. Earlier in his career, Mr. Pavao served as Senior Vice President of Sales and Marketing at Nitromed from July 2004 to July 2006, where he was part of the executive leadership team responsible for the launch of BiDil, and as Chief Executive Officer and Co-Founder of R-Pharm US from February 2014 to June 2018. He frequently advises biotechnology leadership teams and boards on commercialization strategy, portfolio prioritization, and launch readiness. Mr. Pavao holds an MBA from The Wharton School of the University of Pennsylvania and a BA with Highest Honors from the University of North Carolina at Chapel Hill, where he was a Morehead Scholar. Mr. Pavao’s extensive experience in commercial strategy, global market access, and his experience launching innovative medicines underscores his suitability to serve as a director for our company.

Wilbur Ross

Former U.S. Secretary of Commerce
Wilbur L. Ross, Jr. was sworn in by Vice President Mike Pence as the 39th U.S. Secretary of Commerce on February 28, 2017. Secretary Ross is the former Chairman and Chief Strategy Officer of WL Ross & Co. LLC and has over 55 years of investment banking and private equity experience. Secretary Ross has been chairman or lead director of more than 100 companies operating in more than 20 different countries. Named by Bloomberg Markets as one of the 50 most influential people in global finance, Secretary Ross is the only person elected to both the Private Equity Hall of Fame and the Turnaround Management Hall of Fame.

Dieter Weinand

Dieter Weinand is an experienced executive with over 25 years of experience in the pharmaceuticals and biotech industries. Mr. Weinand presently serves as the Chairman of the Board of Directors of Replimune Group Inc. (NASDAQ: REPL), Mnemo Therapeutics, Umoja Biopharma, Inc., Inspirna, Inc., and Ziel Bio, Inc. Previously, Mr. Weinand was Chief Executive Officer and Chairman of the Board of Bayer Pharma AG and member of the Management Board at Bayer AG. Prior to his work at Bayer, Mr. Weinand held various positions in commercial, operational, and strategic areas of the pharmaceutical industry. These included responsibilities spanning various therapeutic areas and geographies for companies such as Pfizer, Bristol Myers Squibb, and Otsuka. Mr. Weinand is a former board member of the Pharmaceutical Research and Manufacturers of America (PhRMA), the European Federation of Pharmaceutical Industries & Associations (EFPIA), and the International Federation of Pharmaceutical Manufacturers (IFPMA), and served as a member of the Board of Directors of HealthPrize Technologies.

Anabella Villalobos, Ph.D.

Biopharmaceutical Executive – Former Biogen, Pfizer

Dr. Anabella Villalobos brings 35 years of biopharmaceutical leadership with Pfizer and
Biogen along with a personal commitment to discovering and delivering medicinal
solutions to patients. Her significant industry experience lies in delivery of development
candidates, INDs, and clinical study results, and advancing partnership opportunities by
building strong relationships and scientific credibility.

From 2017-2025, Dr. Villalobos was head of Biotherapeutics and Medicinal Sciences at
Biogen, where she was responsible for the delivery of high-quality, differentiated drug
candidates for neurological, rare, and auto-immune diseases across multiple modalities,
including small molecules, biologics, oligonucleotides, and gene therapy.

Prior to Biogen, Dr. Villalobos was with Pfizer for 28 years where she most recently
served as Vice President of Medicinal Synthesis Technologies and Neuroscience
Medicinal Chemistry. As the leader of several medicinal chemistry groups throughout
her tenure at Pfizer, Dr. Villalobos’ teams delivered more than 30 small molecule
candidates to combat Alzheimer’s disease, Parkinson’s disease, schizophrenia,
depression, and insomnia. Noteworthy are Ogsiveo® (SpringWorks) and tavapadon
(AbbVie) which reached the market and proof of concept in Phase 3 studies,
respectively. Dr. Villalobos also championed new scientific directions that have improved
design practices in medicinal chemistry including the Central Nervous System Multi-
Parameter Optimization (CNS MPO).

Dr. Villalobos obtained her B.S. in Chemistry at the University of Panama and her Ph.D.
in Medicinal Chemistry at the University of Kansas where she was a Fulbright-Hayes
fellow. She was a National Institutes of Health Postdoctoral Fellow at Yale University in
synthetic organic chemistry for two years.

Ann Lee, Ph.D.

Chief Technical Officer at Prime Medicine

Ann Lee is currently the Chief Technical Officer at Prime Medicine, Inc. She was previously SVP and Head of Cell Therapy Development and Operations (CTDO) at Bristol Myers Squibb from 2019 to July 2021 where she was responsible for developing new cell therapy processes and technologies, manufacturing cell therapy products, designing new facilities, and building the global supply chain to deliver these new medicines for patients. Previously, she served as Executive Vice President of Technical Operations at Juno Therapeutics, which was acquired by BMS via Celgene. Prior to Juno, Dr. Lee joined Genentech in 2005, and she became SVP, Genentech and Head of Global Technical Development at Roche in 2009. She was responsible for developing and delivering all clinical stage products in Roche’s global pipeline, as well as technology transfers and technical support for all commercial products. Earlier, she was at Merck & Co., where she led and developed new vaccines and technologies in R&D, and then was responsible as VP for process engineering and technical operations at 10 chemical sites around the world. Over the course of her career, she has contributed to the development of hundreds of new investigational drugs, and the licensure and commercialization of 25 new vaccines and medicines, with the most recent being two new CAR-T cell products for blood cancers.

Dr. Lee has authored over 40 scientific publications and holds several patents. She is a member of the National Academy of Engineering, fellow of American Academy of Arts and Sciences, American Institute of Medical and Biological Engineering, and member of the Washington State Academy of Sciences. She serves on the Board of Directors for American Institute of Chemical Engineers, the Alliance of Regenerative Medicine, and JW Therapeutics. She earned her undergraduate degree from Cornell University and a masters and Ph.D. in Biochemical Engineering with a concentration in molecular biophysics and biochemistry from Yale University.

Dov Goldstein, M.D., M.B.A.

Chief Financial Officer at BioAge

Dr. Goldstein brings over 20 years of strategic financial and operational experience within the healthcare sector. He currently serves as the Chief Financial Officer at BioAge.Previously, he was the Chief Financial Officer and Chief Business Officer of Indapta Therapeutics, a biotechnology company focused on developing and commercializing a proprietary, off-the-shelf, allogeneic FcRy-deficient natural killer (G-NK) cell therapy to treat multiple types of cancer. Dr. Goldstein was previously Chief Executive Officer of RIGImmune. Prior to that he served as the Chief Financial Officer at Schrödinger, LLC from 2017 to 2018. Dr. Goldstein held various leadership roles at Aisling Capital, a private investment firm, from 2006 to 2017, serving as its Managing Partner from 2014 to 2017. Dr. Goldstein served as the Chief Financial Officer of Loxo Oncology, Inc. between 2014 and 2015. From 2000 to 2005, Dr. Goldstein served as Chief Financial Officer of Vicuron Pharmaceuticals, Inc., raising over $250 million in equity financings, facilitating company partnership transactions and participating in the M&A process when Vicuron was acquired by Pfizer, Inc. for $1.9 billion. Prior to joining Vicuron, he was Director of Venture Analysis at HealthCare Ventures.

Dr. Goldstein currently serves on the board of Directors of NeuBase Therapeutics (Nasdaq: NBSE) and Gain Therapeutics (Nasdaq: GANX). He previously served as a director for ADMA Biologics, Loxo Oncology, Esperion Therapeutics, Duranta Therapeutics, Cempra and a number of private companies. He received a Bachelor of Science in biological sciences from Stanford University, an MBA from Columbia Business School and an M.D. from Yale School of Medicine.

Shimon Sakaguchi M.D., Ph.D.

Member – National Academy of Sciences

Dr. Shimon Sakaguchi is University Distinguished Professor at Osaka University and a member of the National Academy of Sciences. Dr. Sakaguchi is renowned for his discovery of regulatory T cells (Tregs), which can prevent autoimmunity but can also aid tumor survival and is the world’s authority of Treg biology and function. He was awarded the Medal with Purple Ribbon from the Emperor in 2009, designated as Person of Cultural Merit by the Japanese Government in 2017, and has been awarded many international prizes including Cancer Research Institute’s William B. Coley Award, Keio Medical Science Prize, Canada Gairdner International Award and Crafoord Prize.

Clive Svendsen, Ph.D.

Director of the Cedars-Sinai Regenerative Medicine Institute
Professor in Residence at UCLA
Consulting Professor at Stanford Univeristy

Dr. Clive Svendsen is Director of the Cedars-Sinai Regenerative Medicine Institute, Professor in Residence at UCLA and Consulting Professor at Stanford University. Dr. Svendsen is a renowned expert on stem cell biology and regenerative therapeutic approaches. He did his pre-doctoral training at Harvard University and received his PhD from the University of Cambridge in England, where he then established a stem cell research group before moving to the University of Wisconsin in 2000 to become Professor of Neurology and Anatomy, Director of an NIH-funded Stem Cell Training Program and Co-Director of the University of Wisconsin Stem Cell and Regenerative Medicine Center.

Malcolm Brenner, M.D., Ph.D.

Director of the Center for Cell and Gene Therapy and Professor at Baylor College of Medicine

Dr. Brenner is the founding director of the Center for Cell and Gene Therapy and the Fayez Sarofim Distinguished Service Professor at Baylor College of Medicine. He is also a member of the Texas Children’s Cancer and Hematology Center, the Stem Cell and Regenerative Medicine Center, and the Dan L. Duncan Comprehensive Cancer Center at Baylor. Over the past 30 years, Dr. Brenner has devoted his career as a physician-scientist to the field of stem cell transplantation through the therapeutic use of T cell immunologic approaches and genetic engineering strategies. His lab was among the first to study the anti-leukemic effects of IL2 following stem cell transplantation during the 1980s and to study the safety and feasibility of post-transplant immunization. He served as Editor-in-Chief of Molecular Therapy and as former President of the American Society for Gene and Cell Therapy (ASGCT)and International Society for Cell Therapy. Dr. Brenner has earned widespread recognition for his scientific achievements and leadership in the field, including the ASGCT Outstanding Achievement Award, Human Gene Therapy’s Pioneer Award, and the American Society of Hematology Mentor Award. He obtained his BA and medical degrees as well as his Ph.D. from the University of Cambridge in the UK where he became a fellow of the Royal College of Pathologists and the Royal College of Physicians. Dr. Brenner is a co-founder of AlloVir, formerly ViraCyte, LLC.

Stanley Appel, M.D.

Peggy and Gary Edwards Distinguished Endowed Chair for the Treatment and Research of ALS, Co-Director of the Houston Methodist Neurological Institute

Dr. Stanley Appel is the Peggy and Gary Edwards Distinguished Endowed Chair for the Treatment and Research of ALS, Co-Director of the Houston Methodist Neurological Institute, Chair of the Stanley H. Appel Department of Neurology, Houston Methodist Hospital and Professor of Neurology at Weill Cornell Medical College. He is also Director of the MDA/ALSA ALS Research and Clinical Center at the Houston Methodist Neurological Institute. Dr Appel’s seminal research documented the intimate relationship of neurodegeneration and ALS progression with dysfunctional and decreased levels of Tregs. He is also renowned for his discovery of cryopreservation of Tregs, demonstrating the ability to expand, freeze and re-thaw Tregs, while maintaining viability and suppressive function. Dr. Appel is a member of numerous professional societies and committees and has authored 15 books and over 440 articles on topics such as ALS, neuromuscular disease, Alzheimer’s Disease, and Parkinson’s Disease.

Coya is currently enrolling the ALSTARS Phase 2 trial for Coya 302 for people living with ALS across the U.S. and Canada. More information about the ALSTARS trial is available on https://clinicaltrials.gov/study/NCT07161999 or https://trials.coyatherapeutics.com/