Publications

    Publication
    Association between infant and toddler gut microbiota composition and later executive functioning 
    Venla Huovinen et al. Dev Psychopathol. 2026 May 8:1-15. doi: 10.1017/S0954579426101527. Online ahead of print. Published May 8, 2026
    CONCLUSIONS: Alpha diversity in infancy was negatively associated with preschool EF. Additionally, EFs differed between microbial groups based on dominant genera. Bacterial genera abundances were... Read more
    Publication
    Novel CRISPR-Cas9 BAP1 knockout pre-clinical tumor model recapitulates human melanoma tumorigenesis and immune evolution 
    Mona M Wang et al. Commun Biol. 2026 May 5. doi: 10.1038/s42003-026-10118-x. Online ahead of print. Published May 5, 2026
    BAP1-deficient melanocytic tumors exhibit strong immunosuppressive features and poor prognosis. Currently, no immune-competent preclinical models exist to study their tumor-immune interactions or test new immunotherapies.... Read more
    Publication
    Gene-programmed micro-nano metabolic engine drives coupled osteogenic-angiogenic regeneration 
    Wu Yang et al. Biomaterials. 2026 Apr 28;334:124255. doi: 10.1016/j.biomaterials.2026.124255. Online ahead of print. Published May 5, 2026
    Effective bone healing is accompanied by coupled osteogenic-angiogenic regeneration, a process that critically depends on metabolic communication between bone marrow mesenchymal stem cells (BMSCs) and... Read more
    Publication
    Feasibility of multimodal metabolic analysis for detecting early changes in acute neuroinflammation 
    James T Grist et al. J Neuroinflammation. 2026 May 4. doi: 10.1186/s12974-026-03839-7. Online ahead of print. Published May 4, 2026
    Given the prevalence of metabolic perturbations in a variety of neurological and neurodegenerative diseases, understanding and monitoring brain metabolism is a key step in our... Read more
    Publication
    Targeting Sphingosine-1-Phosphate Signaling Attenuates Doxorubicin-Aggravated Bone Loss in Obese Breast Cancer Mice 
    Yu Zhang et al. Smart Med. 2026 Mar 30;5(2):e70031. doi: 10.1002/smmd.70031. eCollection 2026 Apr. Published May 4, 2026
    Although chemotherapy-induced bone loss is well-recognized during breast cancer treatment, the underlying mechanism remains to be further elucidated, especially in patients with obesity. In this... Read more
    Publication
    REACTOR: REgulon Activity analysis and Comparison Tool for single-cell transcriptOmics Research 
    Markus Lindén et al. Bioinformatics. 2026 May 4:btag203. doi: 10.1093/bioinformatics/btag203. Online ahead of print. Published May 4, 2026
    SUMMARY: We introduce REACTOR, a computational tool designed to detect differential activity of transcriptional regulators and their target genes (regulons) in single-cell RNA-sequencing data. It... Read more
    Publication
    Fibrillar adhesion dynamics govern the timescales of nuclear mechano-response via the vimentin cytoskeleton 
    Amy E M Beedle et al. Nat Mater. 2026 Apr 29. doi: 10.1038/s41563-026-02590-x. Online ahead of print. Published April 29, 2026
    The cell nucleus is continuously exposed to external signals, of both chemical and mechanical nature. To ensure proper cellular response, cells need to regulate the... Read more
    Publication
    Therapeutic TG2 inhibition reverses systemic multiomic dysregulation in celiac disease 
    Valeriia Dotsenko et al. BMC Med. 2026 Apr 24. doi: 10.1186/s12916-026-04892-y. Online ahead of print. Published April 24, 2026
    No abstract Read more
    Publication
    Pre- and postnatal maternal psychological distress and the metabolomic profile of human milk 
    Niamh Ryan et al. J Nutr. 2026 Apr 16:101531. doi: 10.1016/j.tjnut.2026.101531. Online ahead of print. Published April 18, 2026
    CONCLUSIONS: Both prenatal and postnatal maternal distress is associated with human milk metabolites. Human milk may buffer infants from some effects of maternal psychological distress,... Read more
    Publication
    The role of human milk oligosaccharides in shaping and restoring infant gut microbiota: Population-based cohort study 
    Minka Ovaska et al. Am J Clin Nutr. 2026 Apr 16:101318. doi: 10.1016/j.ajcnut.2026.101318. Online ahead of print. Published April 18, 2026
    CONCLUSIONS: HMOs exhibit age-dependent and structure-specific associations with infant gut microbiota, extending beyond breastfeeding. Read more
    Publication
    Functional Interplay between Heat Shock Protein 90 (HSP90) and Heat Shock Factors (HSFs) 
    Abir Chakraborty et al. Cell Stress Chaperones. 2026 Apr 9:100177. doi: 10.1016/j.cstres.2026.100177. Online ahead of print. Published April 12, 2026
    Maintenance of protein homeostasis, also known as proteostasis, is essential for cellular survival under both basal and stress conditions. Proteostasis relies on a coordinated action... Read more
    Publication
    Testosterone Exposure During Fetal Masculinization Programming Window Determines the Kidney Size in Adult Mice 
    Arttu Junnila et al. FASEB J. 2026 Apr 15;40(7):e71724. doi: 10.1096/fj.202500761RR. Published April 4, 2026
    Kidney size is sex-dimorphic and regulated by androgens in adult humans and mice. However, the effects of developmental androgen deficiency on kidneys remain elusive. We... Read more
    Last updated on June 25, 2025