[ { "id": 1551, "name": "Indee Labs", "slug": "indee-labs", "former_names": [], "small_logo_thumb_url": "https://bookface-images.s3.amazonaws.com/small_logos/ac1b20e8e540ce71927b19ed6cbc32f9956f9290.png", "website": "http://www.indeelabs.com", "all_locations": "San Francisco, CA, USA; Berkeley, CA, USA", "long_description": "Intracellular delivery is the most problematic step in T cell immunotherapy discovery, development and manufacturing. Indee Labs is developing a non-viral intracellular delivery system based on microfluidic vortex shedding (µVS) to rapidly deliver nucleic acids, proteins and gene editing complexes to patient and donor T cells with minimal perturbation.", "one_liner": "Enabling T cell immunotherapy discovery, development and manufacturing", "team_size": 5, "industry": "Healthcare", "subindustry": "Healthcare -> Drug Discovery and Delivery", "launched_at": 1481766629, "tags": [ "Gene Therapy", "Microfluidics", "Cell Therapy" ], "tags_highlighted": [], "top_company": false, "isHiring": false, "nonprofit": false, "batch": "Winter 2017", "status": "Active", "industries": [ "Healthcare", "Drug Discovery and Delivery" ], "regions": [ "United States of America", "America / Canada", "Remote", "Partly Remote" ], "stage": "Early", "app_video_public": false, "demo_day_video_public": false, "app_answers": null, "question_answers": false, "url": "https://www.ycombinator.com/companies/indee-labs", "api": "https://yc-oss.github.io/api/batches/winter-2017/indee-labs.json" }, { "id": 11979, "name": "LEAH Labs", "slug": "leah-labs", "former_names": [ "Lifengine Animal Health Laboratories", "Incorporated" ], "small_logo_thumb_url": "https://bookface-images.s3.amazonaws.com/small_logos/6907f0370b96042be3d0036ddc25c34015a02b50.png", "website": "http://www.leahlabs.com", "all_locations": "Minneapolis, MN, USA", "long_description": "LEAH Labs is building living therapies for pets first, and their people next. We're first focused on CAR-T cell therapy for dogs with B cell lymphoma, the naturally occurring clinical analog of human non-Hodgkin's lymphoma. CAR-T cells are curative in humans, and our early results are showing the same - we're inducing remissions in pets with late stage lymphomas. Our virus-free gene editing platform allows us to engineer a dose of CAR-T cell therapy for ~$500, and brings the promise of a curative outcome. Given our safety and efficacy data to date, we believe this product could be used by general practice veterinarians, meaning we have thousands of customers all across the USA who typically treat with palliative care or refer cancer patients to specialty oncologists. Our CAR-T cell platform is regulated by the USDA, not the FDA, affording us a cost effective \"full stack\" to iterate and innovate on CAR-T cell therapy from a hypothesis through clinical validation. ", "one_liner": "Living therapies for pets first, and their people next", "team_size": 4, "industry": "Healthcare", "subindustry": "Healthcare -> Therapeutics", "launched_at": 1541131379, "tags": [ "CRISPR", "Cell Therapy", "Drug discovery" ], "tags_highlighted": [], "top_company": false, "isHiring": false, "nonprofit": false, "batch": "Winter 2019", "status": "Active", "industries": [ "Healthcare", "Therapeutics" ], "regions": [ "United States of America", "America / Canada" ], "stage": "Early", "app_video_public": false, "demo_day_video_public": false, "app_answers": null, "question_answers": false, "url": "https://www.ycombinator.com/companies/leah-labs", "api": "https://yc-oss.github.io/api/batches/winter-2019/leah-labs.json" }, { "id": 26311, "name": "WhiteLab Genomics", "slug": "whitelab-genomics", "former_names": [], "small_logo_thumb_url": "https://bookface-images.s3.amazonaws.com/small_logos/ba69864f65b85fda9f05c3280bc3b39f42500013.png", "website": "https://whitelabgx.com", "all_locations": "Paris, Île-de-France, France; Boston, MA, USA", "long_description": "We have developed an AI platform enabling to accelerate the discovery and the design of genomic therapies such as Cell Therapies, RNA Therapies and DNA Therapies.", "one_liner": "Unleashing the potential of DNA and RNA based therapies using AI", "team_size": 40, "industry": "Healthcare", "subindustry": "Healthcare -> Drug Discovery and Delivery", "launched_at": 1644584538, "tags": [ "Artificial Intelligence", "Gene Therapy", "Cell Therapy", "Genomics" ], "tags_highlighted": [], "top_company": false, "isHiring": false, "nonprofit": false, "batch": "Winter 2022", "status": "Active", "industries": [ "Healthcare", "Drug Discovery and Delivery" ], "regions": [ "France", "United States of America", "Europe", "America / Canada", "Remote", "Partly Remote" ], "stage": "Growth", "app_video_public": false, "demo_day_video_public": false, "app_answers": null, "question_answers": false, "url": "https://www.ycombinator.com/companies/whitelab-genomics", "api": "https://yc-oss.github.io/api/batches/winter-2022/whitelab-genomics.json" }, { "id": 26427, "name": "Eugit Therapeutics", "slug": "eugit-therapeutics", "former_names": [ "EUGIT Tx", "EUGIT Therapeutics", "Eugit", "Eugit Therapeutics Inc" ], "small_logo_thumb_url": "https://bookface-images.s3.amazonaws.com/small_logos/a88b74cc086730f852f068c605f2dcaa54b40a16.png", "website": "http://www.eugittx.com", "all_locations": "San Francisco, CA, USA; South San Francisco, CA, USA", "long_description": "Eugit Therapeutics targets the issue of non-specific drugs that cause toxicity and clinical trial failures, affecting millions with tissue-specific inflammatory diseases. TAGHOME delivers drugs with precision to diseased tissues using T cell receptors, enhancing safety and improving efficacy. Our initial focus is on the 3.1 million U.S. individuals with Inflammatory Bowel Disease, aiming to initiate clinical trials within two years.\r\n\r\nCofounded by George Church (Harvard) and funded by Y Combinator (S22).", "one_liner": "Enabling Tissue Targeting of Therapies", "team_size": 2, "industry": "Healthcare", "subindustry": "Healthcare -> Therapeutics", "launched_at": 1656718658, "tags": [ "Cell Therapy", "Synthetic Biology", "Therapeutics", "Oncology", "Biotechnology" ], "tags_highlighted": [], "top_company": false, "isHiring": false, "nonprofit": false, "batch": "Summer 2022", "status": "Active", "industries": [ "Healthcare", "Therapeutics" ], "regions": [ "United States of America", "America / Canada" ], "stage": "Early", "app_video_public": false, "demo_day_video_public": false, "app_answers": null, "question_answers": false, "url": "https://www.ycombinator.com/companies/eugit-therapeutics", "api": "https://yc-oss.github.io/api/batches/summer-2022/eugit-therapeutics.json" }, { "id": 28205, "name": "Modulari-T", "slug": "modulari-t", "former_names": [ "Modulari-T Biosciences" ], "small_logo_thumb_url": "https://bookface-images.s3.amazonaws.com/small_logos/cdfde836f1d168c7ec0299ab6b4daf90d112f929.png", "website": "https://modularit.bio", "all_locations": "Montreal, QC, Canada; San Francisco, CA, USA", "long_description": "Cell and gene therapy promises to one day cure any disease; Modulari-T’s Platform produces the tools to fulfill that promise.\r\n\r\nModulari-T has designed a new family of synthetic genes that can reprogram cells to better sense their environment and modify their behavior accordingly. This can be used to engineer immune cells to efficiently recognize and kill cancer cells or to create stem cells able to regenerate any tissue.\r\n\r\nModulari-T looks to expand its technology to reach every area of cell therapy and become the platform of reference for cell engineering.", "one_liner": "We teach your immune system to attack and cure cancer", "team_size": 4, "industry": "Healthcare", "subindustry": "Healthcare -> Therapeutics", "launched_at": 1675126815, "tags": [ "Gene Therapy", "Cell Therapy", "Synthetic Biology", "Biotech", "Oncology" ], "tags_highlighted": [], "top_company": false, "isHiring": false, "nonprofit": false, "batch": "Winter 2023", "status": "Active", "industries": [ "Healthcare", "Therapeutics" ], "regions": [ "Canada", "United States of America", "America / Canada" ], "stage": "Early", "app_video_public": false, "demo_day_video_public": false, "app_answers": null, "question_answers": false, "url": "https://www.ycombinator.com/companies/modulari-t", "api": "https://yc-oss.github.io/api/batches/winter-2023/modulari-t.json" } ]