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Fifty Years
2,897 posts
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Fifty Years
@fiftyyears
Make something civilization needs. Helping great scientists and engineers become great entrepreneurs is our jam.
San Francisco, CA
substack.fiftyyears.com
Joined July 2016
85
Following
15.3K
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  • Pinned
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    Fifty Years
    @fiftyyears
    Oct 13, 2024
    Make something civilization needs.
    128K
  • Fifty Years reposted
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    Guillermo Rauch
    Vercel
    @rauchg
    9h
    Replying to @goodalexander
    We saw this a lot, so we ran real benchmarks for GLM-5.2 Fast on @vercel AI Gateway, and it's actually fast
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    Vercel Developers
    Vercel
    @vercel_dev
    Jun 24
    GLM 5.2 Fast via Wafer is now available exclusively on Vercel AI Gateway. 2x faster token throughput vs other providers in internal benchmarks. 𝚖𝚘𝚍𝚎𝚕: '𝚣𝚊𝚒/𝚐𝚕𝚖-𝟻.𝟸-𝚏𝚊𝚜𝚝' vercel.com/changelog/glm-…
    7.9K
  • Fifty Years reposted
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    Seth Bannon
    Fifty Years
    @sethbannon
    11h
    Wafer wow
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    Yuchen Jin
    @Yuchenj_UW
    14h
    You may have heard that GLM-5.2 at 328 token/s is cool, How about 392? Databricks is now #1 in inference speed for GLM-5.2 on Artificial Analysis. It's a great model, and we did a lot of optimizations.
    5.8K
  • Fifty Years reposted
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    Matt Loszak
    Aalo Atomics
    @MattLoszak
    12h
    US Energy Secretary Chris Wright has just signed the approval to turn on our first nuclear reactor at the Aalo-X site. And he did the signing live in person! We can now begin to load fuel. It will take a few days—this is a big reactor— but we are on pace to achieve criticality
    63K
  • Fifty Years reposted
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    Marius Hobbhahn
    @MariusHobbhahn
    Jun 22
    We’re hiring for two roles on the monitoring / control team that I’m very excited about: 1. AI security & control engineer: Design threat models for adversarial agents, red-team Watcher and prioritize failure modes Watcher should protect against. 2. Research Scientist
    18K
  • Fifty Years reposted
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    Nabla Bio
    @nablabio
    Jun 23
    Today, we expand zero-shot drug design beyond binding to the design of multifunctional medicines, the intracellular proteome, and state-of-the-art atomic precision with our model, JAM-2. In a new report (below), we show: 1. The first drug-grade, fully computationally designed
    00:00
    169K
  • Fifty Years reposted
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    Seth Bannon
    Fifty Years
    @sethbannon
    Jun 23
    The most exciting field right now is AI × bio. Nabla zero shot designed antibodies straight from from sequence that kill cancer cells at 70 picomolar, spare healthy ones over a single amino acid, and fold exactly as predicted to within an angstrom. Validated, not hype!
    user avatar
    Nabla Bio
    @nablabio
    Jun 23
    Today, we expand zero-shot drug design beyond binding to the design of multifunctional medicines, the intracellular proteome, and state-of-the-art atomic precision with our model, JAM-2. In a new report (below), we show: 1. The first drug-grade, fully computationally designed
    00:00
    91K
  • Fifty Years reposted
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    Seth Bannon
    Fifty Years
    @sethbannon
    Jun 19
    Congratulations to my old boss. Empathy, intelligence, coolness under pressure, and goodness to the core. We need more of this. Was great jamming with him on what we're building at @fiftyyears, and how we can ensure AI creates a better future for humanity.
    6.2K
  • Fifty Years reposted
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    Matt Loszak
    Aalo Atomics
    @MattLoszak
    Jun 1
    "You can't build nuclear quickly" Built our first 10 MW-scale reactor and facility from bare dirt in 5 months. "You can't build nuclear affordably" Only spent $70M in our company history. Includes our real reactor & facility, fuel, prototypes, factory & equipment, payroll,
    176K
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    Fifty Years
    @fiftyyears
    May 29
    Another day another slickly produced video announcing another massive round, often for things that shouldn't exist. "Prediction markets" that are really just online casinos. AI fake-influencer startups built to deceive people. Can't we do better?
    00:00
    1.1M
  • Fifty Years reposted
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    Elicit
    @elicitorg
    May 28
    Elicit now has an MCP server. Use it inside Claude, ChatGPT, Copilot, Gemini, and any MCP-compatible tool. Agents hallucinate when they don't have access to the right evidence. With Elicit's MCP, they search 138M+ papers and cite instead of guess. Ask your agent to run a full
    docs.elicit.com
    Elicit API Reference
    Complete API reference for the Elicit research automation platform. Explore endpoints, parameters, and schemas for programmatic access to Elicit's research tools.
    1.7K
  • Fifty Years reposted
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    ✶ ela ✶
    @elamadej
    May 28
    i think i solved it. Physics PhD, sci-fi writer, AI founder, now a biotech CEO trying to save the world? @hannu must be superhero from a Marvel universe coming to help us out. listen to @ashleevance's pod with Hannu and ponder: 1. How can we be better "parents" to the world
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    Ashlee Vance
    @ashleevance
    May 27
    Good lord he's fun to listen to
    00:00
    6.2K
  • Fifty Years reposted
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    Justin Olshavsky
    @olshav
    May 28
    You should work on problems where being right actually matters
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    Seth Bannon
    Fifty Years
    @sethbannon
    May 26
    Can't we do better? First short film from @fiftyyears.
    00:00
    3.7K

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