Right Where Care Begins

PolyPid is an innovative biopharmaceutical company dedicated to improving patient outcomes by developing long-acting, controlled-release medicines that deliver therapy precisely at the site of care, improving outcomes across surgical care, metabolic diseases, and beyond.

About Us

Redefining the Surgical Standard

Our lead product, D-PLEX100, incorporates the proprietary Kynatrix™ technology and represents a first-in-class incisional prophylactic therapy for the prevention of surgical site infections (SSIs). It introduces long-awaited advancement in SSI prevention by enabling localized, prolonged antibiotic exposure directly at the surgical incision.

By delivering concentrated, broad-spectrum antibiotics at the incision site for 30 days, the most critical postoperative risk period. D-PLEX100 has demonstrated a clinically meaningful 60% reduction in surgical site infections compared with standard of care.

Learn More about D-PLEX100
Icon & surgion

Constant and Consistent Drug Release

The Kynatrix™ technology enables customizable, localized, extended drug delivery over periods ranging from days to weeks, without burst effects, ensuring linear, high-concentration exposure across a broad range of therapeutic agents.

Our technology
Doctor & patient
tm-icon

Novel, Proprietary
 Technology

validated-icon

Validated, 
Clinically Proven

Unmatched Application 
Versatility  

robust-icon

Robust Innovative
Pipeline

Contact Us

    Contact icon