The Porta family's commitment to our Dup15q ASO program is deeply personal — and it brings us meaningfully closer to the first disease-modifying treatment for this condition. We're grateful and proud to share this milestone with the Dup15q community. View full press release here 🔗https://lnkd.in/eN_k7zdu Dup15q Alliance Jose Antonio Porta #Dup15q #Neuroscience #DrugDiscovery
Quiver Bioscience
Biotechnology Research
Cambridge, MA 6,403 followers
Decoding Brain Disease to Reimagine Drug Development
About us
Quiver is a technology-driven company established to create transformational medicines for the brain while simultaneously uncovering new biology and novel, effective drug targets. Using advanced single cell imaging and multi-omics, we are building the world's most information-rich neuronal insight map "Genomic Positioning System" through state-of-the-art proprietary engineering and AI/ML approaches.
- Website
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http://www.quiverbioscience.com
External link for Quiver Bioscience
- Industry
- Biotechnology Research
- Company size
- 51-200 employees
- Headquarters
- Cambridge, MA
- Type
- Privately Held
- Founded
- 2013
- Specialties
- Precision Medicine, Machine Learning, Genomics, Neurology, Drug Discovery, Personalized Medicine, Genetic Therapies, Optical Electrophysiology, Gene Editing, Stem Cells, Optogenetics, Transcriptomics, Human Models, Therapeutic Design & Screening, Cardiology, Rare Disease, Neurodegenerative, Disrupting Medicine, and Functional Genomics
Locations
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Primary
Get directions
179 Sidney Street
Cambridge, MA 02139, US
Employees at Quiver Bioscience
Updates
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The brain speaks with a unique language - electrical signals firing across billions of neurons, driving thought, movement, emotion, and memory. When that language breaks down, the consequences are profound: epilepsy, ALS, rare neurodevelopmental disorders, and countless conditions that have long resisted conventional drug discovery. At Quiver Bioscience, we've built a platform designed to listen and translate. The result is a fundamentally different foundation for CNS drug discovery grounded in neuronal function. The Quiver team celebrates Brain Awareness Week 2026 🧠 #BrainAwarenessWeek #Neuroscience #CNS #DrugDiscovery
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Congratulations to this year’s Brain Prize winners – David Ginty and Patrik Ernfors. Their foundational work in sensory neuron biology has transformed our understanding of how pain signals are generated and maintained in the nervous system. These foundational insights are now enabling the next generation of pain therapeutics including Quiver’s own novel non-opioid treatment for chronic pain.
Huge congratulations to the Brain Prize winners of 2026! This year's Brain Prize is awarded to Professors David Ginty (Harvard Medical School, US) and Patrik Ernfors (Karolinska Institutet, Sweden) for their pioneering discoveries on how the nervous system detects and processes touch and pain. Together, their work has transformed our understanding of how stimuli are detected and transduced into neural signals, and how these signals are processed and integrated as they travel to the brain to allow perception of our physical interactions with the world. For decades, scientists lacked a clear understanding of how many distinct sensory neuron types exist, how they are constructed, and how their signals are organized and routed to the central nervous system. The Brain Prize winners have radically changed the field. By identifying and classifying distinct sensory neuron types, linking them to specific end organs and neural pathways, and developing widely used genetic and molecular tools, they have established a blueprint for understanding touch and pain—and for pinpointing what goes wrong in conditions such as chronic pain and hypersensitivity. Their work has rewritten textbook principles of somatosensation and provided the foundation for a new generation of targeted interventions for pain and disorders of touch based on specific cell types and neural pathways. Learn more about the two prize winners and their discoveries: https://lnkd.in/eQk9TayB Howard Hughes Medical Institute (HHMI)
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Rare Disease Day is a powerful reminder of why we at Quiver Bioscience dedicate ourselves to this work every day. Thank you to Charlene Son Rigby (STXBP1 Foundation), Emily Barnes (Cure SYNGAP1), and Isabel Aznarez (Stoke Therapeutics) for joining us at Quiver last week to share unique perspectives on rare neurological disorders! From individual lived experiences with STXBP1 and SYNGAP1-related disorders to the inspiring story of ASO therapeutic development for Dravet syndrome, the conversation underscored the power of collaboration between patients, advocates, and researchers. Progress in rare diseases depends on listening, partnership, and persistence. We’re proud to stand alongside this community in advancing therapies for rare neurological diseases. #RareDiseaseDay2026 #Biotech #Neuroscience
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Quiver Bioscience proudly supports Rare Disease Day 2026. We stand with the global rare disease community and remain dedicated to advancing science that can transform the lives of patients and families affected by rare neurological disorders. #RareDiseaseDay2026 #RareDiseaseAwareness
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Quiver Bioscience reposted this
We’re excited to announce a strategic research collaboration and licensing agreement with Angelini Pharma to discover and advance novel therapeutics for genetic epilepsies, including Developmental and Epileptic Encephalopathies (DEEs). This multi-year partnership combines Quiver’s GPS platform—human neuronal models, single-cell multimodal data, optical electrophysiology, and AI-driven analytics—with Angelini Pharma’s deep expertise in brain health and epilepsy drug development. Together, we aim to generate new functional and molecular insights to help unlock differentiated therapeutic targets for patients with urgent unmet need. 📰 Read the full press release here: https://lnkd.in/eSF8hJXh #Epilepsy #Neuroscience #DrugDiscovery #PrecisionMedicine #AIinBiotech #BrainHealth
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We’re excited to announce a strategic research collaboration and licensing agreement with Angelini Pharma to discover and advance novel therapeutics for genetic epilepsies, including Developmental and Epileptic Encephalopathies (DEEs). This multi-year partnership combines Quiver’s GPS platform—human neuronal models, single-cell multimodal data, optical electrophysiology, and AI-driven analytics—with Angelini Pharma’s deep expertise in brain health and epilepsy drug development. Together, we aim to generate new functional and molecular insights to help unlock differentiated therapeutic targets for patients with urgent unmet need. 📰 Read the full press release here: https://lnkd.in/eSF8hJXh #Epilepsy #Neuroscience #DrugDiscovery #PrecisionMedicine #AIinBiotech #BrainHealth
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Today we recognize the extraordinary contributions of women in science — including the researchers and leaders at Quiver Bioscience who are redefining what’s possible in neurotherapeutics. #WomenInSTEM
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We’re excited to share our newly redesigned website! 🔬 A clearer story, improved navigation, and a better view of our science. 💻 Take a look: www.quiverbioscience.com
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Our CEO, Graham T. Dempsey, was recently interviewed on #TheGeneticsPodcast by Sano Genetics—a show dedicated to exploring cutting-edge science and breakthroughs in genetics research. In this episode, Graham discusses his journey into neuroscience and biotech, Quiver Bioscience's mission to transform CNS drug discovery, and how Quiver is advancing genetically validated therapeutics programs for pain and neurodevelopmental disorders. 🎧 Listen here: https://lnkd.in/edfS4C_6
🎙️Episode 220 of #TheGeneticsPodcast is live! 🚀 This week, Patrick is joined by Graham Dempsey, CEO and co-founder of Quiver Bioscience. Tune in as they discuss: 🧠 How genetically validated sodium channel targets like Nav1.7 are reshaping approaches to chronic neuropathic pain 🧬 Quiver’s lead pain program and Dup15q neurodevelopmental program 🚀 The opportunities and tradeoffs of building a platform biotech at the intersection of RNA medicine and neuroscience Listen by following the link below 👇 or simply search “The Genetics Podcast” on your go-to podcast platform. 🎧 https://lnkd.in/eATyZm6n 📽️ https://lnkd.in/eCAanKfY Please consider rating and reviewing us on your chosen podcast listening platform! #Genetics #PrecisionMedicine #DrugDiscovery #PainDisorders #Neurodevelopment
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