Glen Research is proud to sponsor the Telluride Science Nucleic Acid Chemistry workshop, where researchers from academia and industry come together to explore cutting-edge topics related to related to nucleic acids. We're excited to support the conversations that can move nucleic acid chemistry forward as attendees explore the scenery, new ideas, and collaboration.
Glen Research
Biotechnology
Sterling, VA 3,619 followers
Oligonucleotide synthesis success. The first time and every time.
About us
Glen Research, part of Maravai LifeSciences, is a leading provider of reagents for DNA and RNA oligonucleotide synthesis, labeling, and modification. Known for its proprietary Sterling™ line of reagents marked with its Sterling Seal of Quality Assurance, Glen analyzes and certifies these reagents for purity and performance ensuring consistent, dependable and reliable results. Glen also specializes in oligonucleotide purification supplies under the Glen-Pak™ and Glen Gel-Pak™ product lines. Glen supplies its reagents to: researchers investigating diverse genetic diseases and disorders; businesses and organizations developing new genetic therapies; and, biopharmaceutical, diagnostic and life science OEM partners who incorporate Glen Research offerings into their own products. Glen takes pride in delivering operational excellence, experienced technical support and superior customer service and is ISO 9001:2015 certified. As part of its Quality Management System, Glen verifies that its operations and processes meet all management criteria for consistency and performance. Glen was founded in 1987 by Hugh and Margaret Mackie with a mission to provide state-of-the art reagents to researchers. In 1993, Glen introduced the Sterling line of products, a new standard of accomplishment for oligonucleotide synthesis. Headquartered in Sterling, Virginia, Glen Research is online at www.glenresearch.com.
- Website
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http://www.glenresearch.com
External link for Glen Research
- Industry
- Biotechnology
- Company size
- 11-50 employees
- Headquarters
- Sterling, VA
- Type
- Privately Held
- Founded
- 1986
- Specialties
- Nucleoside phosphoramidites and supports for oligonucleotide synthesis, Reagents for modification and labeling of oligonucleotides, and Glen-Pak™ line of products for oligonucleotide purification
Employees at Glen Research
View 32 employees at Glen Research
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Locations
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Get directions
22825 Davis Dr
Sterling, VA 20164, US
Updates
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As a provider of phosphoramidites, modifiers, linkers, and solid supports for more than 35 years, Glen Research is proud to sponsor the 22nd RSC Nucleic Acids Forum and support the scientific community advancing nucleic acid research at the interface of chemistry, biology, and physics. Here's to a productive and inspiring meeting filled with insightful discussions, new collaborations, and exciting scientific discoveries!
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As #oligonucleotides continue to increase in complexity, efficient methods for assembling longer, functional constructs are more important than ever. In our latest application note, we explore how CuAAC click chemistry and triazole linkages are enabling researchers to ligate shorter oligonucleotide fragments into longer sequences while maintaining biological compatibility. We also highlight emerging applications—including ClickSeq, synthetic biology, and chemically defined nucleic acid architectures—and discuss practical considerations for implementing this approach. Read the latest update and discover how Glen Research reagents support modular oligonucleotide assembly: https://ow.ly/kVEO50ZhIEW
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What special phosphoramidites are required for phosphorothioate synthesis? The answer is none. The standard method of introducing phosphorothioates is to use standard phosphoramidites and sulfurization reagent in place of standard iodine oxidation. Sulfurization requires a contact time of at least one minute on the synthesizer. Sulfurization also needs to occur before capping, in the opposite order when compared to standard iodine oxidation. This is to prevent trace amounts of peroxides in capping reagents from performing undesired oxidation. Products: Sulfurizing Reagent II (40-4037) 0.05M Sulfurizing Reagent II in pyridine/acetonitrile (40-4137) 💡 Interested in more #oligonucleotide synthesis insights like this? 📩 Subscribe to our newsletter, The Glen Report, to keep up with the latest! https://ow.ly/WIz050Q87rb
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Efficient synthesis of long #oligonucleotides can be challenging with traditional solid-phase methods, especially as chain length increases. One promising alternative is click ligation via CuAAC, which enables the assembly of shorter fragments into longer, chemically stable constructs using a triazole linkage. This approach offers several advantages, including mild reaction conditions, high selectivity, and strong compatibility with downstream applications such as PCR, in vitro transcription, and sequencing workflows. Read more in our latest application note on triazole linkages for oligonucleotide ligation: https://ow.ly/AGlo50ZeoMn
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Thanks to everyone who stopped by our booth at TIDES USA 2026 and for the great conversations around supply continuity, custom reagents, and oligonucleotide synthesis! #TIDES2026
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Last day at #TIDES2026 in Boston - hope we didn't miss you! There's time to swing by booth 811 before we pack up. Grab a shirt, the latest Glen Report, and let's talk about your oligonucleotide synthesis reagent needs!
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Day 1 at TIDES USA 2026 is underway! Our team is on the exhibit floor at Booth 811 to talk about: 🚚 Long‑term supply for oligonucleotide reagents ⚗️ Custom synthesis & packaging options 🧬 Diagnostic & therapeutic #oligonucleotide modifications Swing by today, tomorrow, or the day after! #TIDES2026
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