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Microbial Fermentation Services

Microbial Fermentation Services

BOC Sciences has more than 20 years of experience in microbial fermentation and meets customer needs through a complete service product line from strain development to large-scale manufacturing. We are experts in microbial fermentation based on bacteria, fungi, and yeast-from strain selection, optimization, and process development to scale-up and GMP production. Based on our stable and safe fermentation raw material supply chain, we can achieve a high-quality, cost-effective biological fermentation process.

Microbial Fermentation GMP Production

Microbial Fermentation Services

Microbial Fermentation Services

Fermentation for special small molecules

Different from conventional synthetic small molecules, the small molecules obtained through fermentation,  produced in the culture of living cells, are usually more bioactive and cost-effective.

Fermentation process development, validation, and optimization

We provide services for strain development, process optimization, and large-scale manufacturing, helping customers bring their products to the market.

GRAS Services

Our strain gene identification platform can help quickly confirm the identity of the strain and ensure that the strains used in your project are of the GRAS (Generally Recognized as Safe) level.

We provide CDMO service to worldwide partners in big pharma, biotech and biopharma companies with solutions for the development and biomanufacturing of a broad range of biological molecules.

Downstream process optimization (microfiltration, centrifugation, liquid/liquid extraction, ultrafiltration, evaporation, packaging)

Application of Microbial Fermentation

Fermentation engineering has the characteristics of mild production conditions, rich sources of raw materials and low price, specific products, low environmental pollution, and easy disposal of waste. It has been widely used in the pharmaceutical industry, food industry, agriculture, metallurgy industry, environmental protection, and many other fields, and gradually formed a large-scale fermentation industry.

As far as the application of fermentation engineering in the pharmaceutical industry is concerned, it has achieved remarkable results, such as antibiotics, vitamins, animal hormones, medicinal amino acids, nucleotides (such as inosine), and so on. At present, there are more than 100 kinds of antibiotics, such as penicillins, cephalosporins, erythromycin, and tetracyclines. In addition, a large number of genetic engineering drugs are produced by fermentation engineering, such as human growth hormone, recombinant hepatitis B vaccine, some kinds of monoclonal antibodies, IL-2, anti-hemophilia factor, and so on.

Our fermentation services can be used to produce:

ProteinsEnzymesSecondary metabolites
Modified peptidesAntibodiesAdvanced chemicals
CarbohydratesImpuritiesEnzyme biotransformation products

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Our Capabilities

Our Facilities

Laboratory

Semi Pilot, Pilot and Industrial Plant

Main Equipment

The integrated fermentation and purification development of BOC Sciences, as well as the analysis and development team, work together to achieve the highest quality of products while maintaining flexibility to meet the needs of the plan.

Frequently Asked Questions (FAQ)

What is the advantage of microbial fermentation over traditional chemical synthesis?

Microbial fermentation is more cost-effective, environmentally friendly, and suitable for producing complex and bioactive small molecules.

We use a wide range of microorganisms, including bacteria, fungi, yeast, and genetically modified organisms (GMOs) for diverse fermentation processes.

We ensure high-quality production through stringent process optimization, quality control in our microbiological and chemical labs, and adherence to established manufacturing standards.

We provide fermentation services at various scales, from laboratory (1-15L) to industrial production (up to 4,000L), offering flexibility to meet your production needs.

Our services support the production of proteins, enzymes, secondary metabolites, modified peptides, antibodies, and advanced chemicals, among others.

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