The Pittsburgh Center for AI Innovation in Medical Imaging (CAIIMI) was launched in January 2020 and has engaged 124 members from 9 different schools at the University of Pittsburgh, the University of Pittsburgh Medical Center, and Carnegie Mellon University. CAIIMI’s vision is to build a center for advanced innovative AI research, education, clinical translation, commercialization, and collaborations in medical imaging by synergizing computational expertise and clinical resources in Pittsburgh, resulting in a world-class imaging AI research and translation center.