John Barrymore Don Jose de Marana / Don Juan de Marana Jane Winton Donna Isobel John Roche Leandro Warner Oland Cesare Borgia Estelle Taylor Lucrezia Borgia Montagu Love Count Giano Donati Josef Swickard Duke Della Varnese Willard Louis Pedrillo Nigel De Brulier Marchese Rinaldo Hedda Hopper Marchesia Rinaldo Myrna Loy Mai - Lady in Waiting Mary Astor Adriana della Varnese Lionel Braham Duke Margoni (uncredited) Helene Costello Rena - Adriana's Maid (uncredited) Helena D'Algy Donna Elvira (uncredited) Jacob Dance Gentleman (uncredited) Yvonne Day Don Juan - at age 5 (uncredited) Philippe De Lacy Don Juan - at age 10 (uncredited) Emily Fitzroy The Dowager (uncredited) John George Hunchback (uncredited) Alan Crosland Director Byron Haskin Director Gordon Hollingshead Director