Platform Updates https://updates.varsome.com/en Follow the latest updates to all VarSome platforms. en Thu, 23 Apr 2026 05:59:59 GMT 2026-04-23T05:59:59Z en VarSome, VarSome API, & VarSome Clinical v.13.16.1.0 https://updates.varsome.com/en/varsome-v.13.16 <p style="font-size: 16px;"><span style="color: #000000;"><span style="color: #000000;">Version 13.16.1.0&nbsp;of VarSome, <a href="https://landing.varsome.com/varsome-api">VarSome API</a>, and <a href="https://landing.varsome.com/varsome-clinical">VarSome Clinical</a> was released on 23 April 2026.</span></span></p> <h1 style="font-size: 20px;"><span style="color: #000000;">Summary of Key New Features</span></h1> <ul> <li style="font-size: 16px;"><span style="color: #000000;">20 updated databases</span> (<a href="https://varsome.com/datasources/">full list of databases</a>).</li> </ul> <table style="border-collapse: collapse; table-layout: fixed; margin-left: auto; margin-right: auto; border: 1px solid #99acc2; width: 81%; height: 1851.59px;"> <colgroup> <col style="width: 45.0508%;"> <col style="width: 27.3088%;"> <col style="width: 27.6567%;"> </colgroup> <tbody> <tr style="height: 71.5938px;"> <th style="height: 71.5938px; border-style: solid; text-align: center; background-color: #9fc5e8; border-color: #000000;"> <p><strong>Database </strong></p> </th> <th style="height: 71.5938px; border-style: solid; text-align: center; background-color: #9fc5e8; border-color: #000000;"> <p><strong>Old version </strong></p> </th> <th style="height: 71.5938px; border-style: solid; text-align: center; background-color: #9fc5e8; border-color: #000000;"> <p><strong>New version </strong></p> </th> </tr> <tr style="height: 89px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">CPIC</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">07-Mar-2026</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; text-align: center; height: 89px;"><span style="color: #000000;">07-Apr-2026</span></td> </tr> <tr style="height: 89px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">AACT</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">07-Mar-2026</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; text-align: center; height: 89px;"><span style="color: #000000;">07-Apr-2026</span></td> </tr> <tr style="height: 89px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">GWAS</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">07-Mar-2026</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; text-align: center; height: 89px;"><span style="color: #000000;">07-Apr-2026</span></td> </tr> <tr style="height: 89px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">gene2phenotype</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">07-Mar-2026</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; text-align: center; height: 89px;"><span style="color: #000000;">07-Apr-2026</span></td> </tr> <tr style="height: 89px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">CKB</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">17-Mar-2026</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; text-align: center; height: 89px;"><span style="color: #000000;">14-Apr-2026</span></td> </tr> <tr style="height: 89px;"> <td style="padding: 4px; height: 89px; border: 1px solid #000000;"> <p style="text-align: center;"><span style="color: #000000;">OMIM®</span></p> </td> <td style="padding: 4px; height: 89px; border: 1px solid #000000;"> <p style="text-align: center;"><span style="color: #000000;">&nbsp;17-Mar-2026</span></p> </td> <td style="text-align: center; padding: 4px; height: 89px; border: 1px solid #000000;"><span style="color: #000000;">&nbsp;14-Apr-2026</span></td> </tr> <tr style="height: 89px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">LOVD</span></p> </td> <td style="padding: 4px; height: 89px; border: 1px solid #000000;"> <p style="text-align: center;"><span style="color: #000000;">&nbsp;17-Mar-2026</span></p> </td> <td style="text-align: center; padding: 4px; height: 89px; border: 1px solid #000000;"><span style="color: #000000;">&nbsp;14-Apr-2026</span></td> </tr> <tr style="height: 89px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">OncoKB</span></p> </td> <td style="border: 1px solid #000000; padding: 4px; height: 89px;"> <p style="text-align: center; font-weight: normal;"><span style="color: #000000;">v6.1</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">v7.0</span></p> </td> </tr> <tr style="height: 89px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">HPO</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">07-May-2025</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; text-align: center; height: 89px;"><span style="color: #000000;">07-Apr-2026</span></td> </tr> <tr style="height: 89px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">ClinVar</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 178px;" rowspan="2"> <p style="text-align: center;"><span style="color: #000000;">07-Mar-2026</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 178px; text-align: center;" rowspan="2"><span style="color: #000000;">07-Apr-2026</span></td> </tr> <tr style="height: 89px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">ClinVar CNVs</span></p> </td> </tr> <tr style="height: 89px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">ClinGen</span></p> </td> <td style="border: 1px solid #000000; padding: 4px; height: 445px;" rowspan="5"> <p style="text-align: center;"><span style="color: #000000;">07-Mar-2026</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 445px;" rowspan="5"> <p style="text-align: center;"><span style="color: #000000;">07-Apr-2026</span></p> </td> </tr> <tr style="height: 89px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">ClinGen CNVs</span></p> </td> </tr> <tr style="height: 89px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">ClinGen Disease Validity</span></p> </td> </tr> <tr style="height: 89px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">ClinGen Regions</span></p> </td> </tr> <tr style="height: 89px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">ClinGen Variants</span></p> </td> </tr> <tr style="height: 89px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89px; text-align: center;"> <p><span style="color: #000000;">PharmGKB</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">07-Mar-2026</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89px; text-align: center;"><span style="color: #000000;">07-Apr-2026</span></td> </tr> <tr style="height: 89px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89px; text-align: center;"> <p><span style="color: #000000;">DECIPHER</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">07-Mar-2026</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89px; text-align: center;"><span style="color: #000000;">07-Apr-2026</span></td> </tr> <tr style="height: 89px;"> <td style="border: 1px solid #000000; padding: 4px; text-align: center; height: 89px;"> <p><span style="color: #000000;">CGC</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">v102</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; text-align: center; height: 89px;"><span style="color: #000000;">v103</span></td> </tr> <tr style="height: 89px;"> <td style="border: 1px solid #000000; padding: 4px; text-align: center; height: 89px;"> <p><span style="color: #000000;">DGV</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">30-Jun-2021</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; text-align: center; height: 89px;"><span style="color: #000000;">07-Apr-2026</span></td> </tr> </tbody> </table> <p style="font-size: 16px;">&nbsp;</p> <p style="font-size: 16px;"><span style="color: #000000;"><span style="color: #000000;">Version 13.16.1.0&nbsp;of VarSome, <a href="https://landing.varsome.com/varsome-api">VarSome API</a>, and <a href="https://landing.varsome.com/varsome-clinical">VarSome Clinical</a> was released on 23 April 2026.</span></span></p> <h1 style="font-size: 20px;"><span style="color: #000000;">Summary of Key New Features</span></h1> <ul> <li style="font-size: 16px;"><span style="color: #000000;">20 updated databases</span> (<a href="https://varsome.com/datasources/">full list of databases</a>).</li> </ul> <table style="border-collapse: collapse; table-layout: fixed; margin-left: auto; margin-right: auto; border: 1px solid #99acc2; width: 81%; height: 1851.59px;"> <colgroup> <col style="width: 45.0508%;"> <col style="width: 27.3088%;"> <col style="width: 27.6567%;"> </colgroup> <tbody> <tr style="height: 71.5938px;"> <th style="height: 71.5938px; border-style: solid; text-align: center; background-color: #9fc5e8; border-color: #000000;"> <p><strong>Database </strong></p> </th> <th style="height: 71.5938px; border-style: solid; text-align: center; background-color: #9fc5e8; border-color: #000000;"> <p><strong>Old version </strong></p> </th> <th style="height: 71.5938px; border-style: solid; text-align: center; background-color: #9fc5e8; border-color: #000000;"> <p><strong>New version </strong></p> </th> </tr> <tr style="height: 89px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">CPIC</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">07-Mar-2026</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; text-align: center; height: 89px;"><span style="color: #000000;">07-Apr-2026</span></td> </tr> <tr style="height: 89px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">AACT</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">07-Mar-2026</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; text-align: center; height: 89px;"><span style="color: #000000;">07-Apr-2026</span></td> </tr> <tr style="height: 89px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">GWAS</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">07-Mar-2026</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; text-align: center; height: 89px;"><span style="color: #000000;">07-Apr-2026</span></td> </tr> <tr style="height: 89px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">gene2phenotype</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">07-Mar-2026</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; text-align: center; height: 89px;"><span style="color: #000000;">07-Apr-2026</span></td> </tr> <tr style="height: 89px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">CKB</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">17-Mar-2026</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; text-align: center; height: 89px;"><span style="color: #000000;">14-Apr-2026</span></td> </tr> <tr style="height: 89px;"> <td style="padding: 4px; height: 89px; border: 1px solid #000000;"> <p style="text-align: center;"><span style="color: #000000;">OMIM®</span></p> </td> <td style="padding: 4px; height: 89px; border: 1px solid #000000;"> <p style="text-align: center;"><span style="color: #000000;">&nbsp;17-Mar-2026</span></p> </td> <td style="text-align: center; padding: 4px; height: 89px; border: 1px solid #000000;"><span style="color: #000000;">&nbsp;14-Apr-2026</span></td> </tr> <tr style="height: 89px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">LOVD</span></p> </td> <td style="padding: 4px; height: 89px; border: 1px solid #000000;"> <p style="text-align: center;"><span style="color: #000000;">&nbsp;17-Mar-2026</span></p> </td> <td style="text-align: center; padding: 4px; height: 89px; border: 1px solid #000000;"><span style="color: #000000;">&nbsp;14-Apr-2026</span></td> </tr> <tr style="height: 89px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">OncoKB</span></p> </td> <td style="border: 1px solid #000000; padding: 4px; height: 89px;"> <p style="text-align: center; font-weight: normal;"><span style="color: #000000;">v6.1</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">v7.0</span></p> </td> </tr> <tr style="height: 89px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">HPO</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">07-May-2025</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; text-align: center; height: 89px;"><span style="color: #000000;">07-Apr-2026</span></td> </tr> <tr style="height: 89px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">ClinVar</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 178px;" rowspan="2"> <p style="text-align: center;"><span style="color: #000000;">07-Mar-2026</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 178px; text-align: center;" rowspan="2"><span style="color: #000000;">07-Apr-2026</span></td> </tr> <tr style="height: 89px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">ClinVar CNVs</span></p> </td> </tr> <tr style="height: 89px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">ClinGen</span></p> </td> <td style="border: 1px solid #000000; padding: 4px; height: 445px;" rowspan="5"> <p style="text-align: center;"><span style="color: #000000;">07-Mar-2026</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 445px;" rowspan="5"> <p style="text-align: center;"><span style="color: #000000;">07-Apr-2026</span></p> </td> </tr> <tr style="height: 89px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">ClinGen CNVs</span></p> </td> </tr> <tr style="height: 89px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">ClinGen Disease Validity</span></p> </td> </tr> <tr style="height: 89px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">ClinGen Regions</span></p> </td> </tr> <tr style="height: 89px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">ClinGen Variants</span></p> </td> </tr> <tr style="height: 89px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89px; text-align: center;"> <p><span style="color: #000000;">PharmGKB</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">07-Mar-2026</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89px; text-align: center;"><span style="color: #000000;">07-Apr-2026</span></td> </tr> <tr style="height: 89px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89px; text-align: center;"> <p><span style="color: #000000;">DECIPHER</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">07-Mar-2026</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89px; text-align: center;"><span style="color: #000000;">07-Apr-2026</span></td> </tr> <tr style="height: 89px;"> <td style="border: 1px solid #000000; padding: 4px; text-align: center; height: 89px;"> <p><span style="color: #000000;">CGC</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">v102</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; text-align: center; height: 89px;"><span style="color: #000000;">v103</span></td> </tr> <tr style="height: 89px;"> <td style="border: 1px solid #000000; padding: 4px; text-align: center; height: 89px;"> <p><span style="color: #000000;">DGV</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">30-Jun-2021</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; text-align: center; height: 89px;"><span style="color: #000000;">07-Apr-2026</span></td> </tr> </tbody> </table> <p style="font-size: 16px;">&nbsp;</p> <img src="https://track.hubspot.com/__ptq.gif?a=4384097&amp;k=14&amp;r=https%3A%2F%2Fupdates.varsome.com%2Fen%2Fvarsome-v.13.16&amp;bu=https%253A%252F%252Fupdates.varsome.com%252Fen&amp;bvt=rss" alt="" width="1" height="1" style="min-height:1px!important;width:1px!important;border-width:0!important;margin-top:0!important;margin-bottom:0!important;margin-right:0!important;margin-left:0!important;padding-top:0!important;padding-bottom:0!important;padding-right:0!important;padding-left:0!important; "> Platform Updates VarSome API VarSome Clinical VarSome.com Premium Release Tue, 21 Apr 2026 05:00:00 GMT xanthippi.papakonstanti@saphetor.com (Xanthippi Papakonstanti) https://updates.varsome.com/en/varsome-v.13.16 2026-04-21T05:00:00Z VarSome, VarSome API, & VarSome Clinical v.13.15.1.1 https://updates.varsome.com/en/varsome-v.13.15 <p style="font-size: 16px;"><span style="color: #000000;"><span style="color: #000000;">Version 13.15.1.1 of <a href="https://landing.varsome.com/varsome-clinical">VarSome Clinical</a> was released on 16 April 2026.</span></span></p> <h1 style="font-size: 20px;"><span style="color: #000000;">Summary of Key New Features</span></h1> <ul> <li style="font-size: 16px;"> <p><span style="color: #000000;"><span style="color: #000000;">Fixed issues in somatic classification and sample display, and improving overall result reliability.</span></span></p> </li> </ul> <p style="font-size: 16px;">&nbsp;</p> <p style="font-size: 16px;"><span style="color: #000000;"><span style="color: #000000;">Version 13.15.1.0&nbsp;of VarSome, <a href="https://landing.varsome.com/varsome-api">VarSome API</a>, and <a href="https://landing.varsome.com/varsome-clinical">VarSome Clinical</a> was released on 26 March 2026.</span></span></p> <h1 style="font-size: 20px;"><span style="color: #000000;">Summary of Key New Features</span></h1> <ul> <li style="color: #1d1c1d;">Resolved an issue affecting access to CNV results for assigned samples, along with minor inconsistencies in roles and permissions.</li> <li style="color: #1d1c1d;">Fixed an edge case where the PP5 rule could be incorrectly triggered by somatic evidence in germline variant classification.</li> <li style="color: #1d1c1d;">General UI and UX improvements, along with minor bug fixes.</li> <li style="font-size: 16px;"><span style="color: #000000;">20 updated databases</span> (<a href="https://varsome.com/datasources/">full list of databases</a>).</li> </ul> <table style="border-collapse: collapse; table-layout: fixed; margin-left: auto; margin-right: auto; border: 1px solid #99acc2; width: 81%;"> <colgroup> <col style="width: 45.0508%;"> <col style="width: 27.3088%;"> <col style="width: 27.6567%;"> </colgroup> <tbody> <tr style="height: 71.5938px;"> <th style="height: 71.5938px; border-style: solid; text-align: center; background-color: #9fc5e8; border-color: #000000;"> <p><strong>Database </strong></p> </th> <th style="height: 71.5938px; border-style: solid; text-align: center; background-color: #9fc5e8; border-color: #000000;"> <p><strong>Old version </strong></p> </th> <th style="height: 71.5938px; border-style: solid; text-align: center; background-color: #9fc5e8; border-color: #000000;"> <p><strong>New version </strong></p> </th> </tr> <tr style="height: 89px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">CPIC</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">07-Jan-2026</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; text-align: center; height: 89px;"><span style="color: #000000;">07-Mar-2026</span></td> </tr> <tr style="height: 89px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">AACT</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">07-Feb-2026</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89px; text-align: center;"><span style="color: #000000;">07-Mar-2026</span></td> </tr> <tr style="height: 89px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">GWAS</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">07-Feb-2026</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89px; text-align: center;"><span style="color: #000000;">07-Mar-2026</span></td> </tr> <tr style="height: 89px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">gene2phenotype</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">07-Feb-2026</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89px; text-align: center;"><span style="color: #000000;">07-Mar-2026</span></td> </tr> <tr style="height: 89px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">CKB</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">14-Mar-2026</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; text-align: center; height: 89px;"><span style="color: #000000;">17-Mar-2026</span></td> </tr> <tr style="height: 89px;"> <td style="padding: 4px; height: 89px; border: 1px solid #000000;"> <p style="text-align: center;"><span style="color: #000000;">OMIM®</span></p> </td> <td style="padding: 4px; height: 89px; border: 1px solid #000000;"> <p style="text-align: center;"><span style="color: #000000;">&nbsp;19-Jan-2026</span></p> </td> <td style="text-align: center; padding: 4px; height: 89px; border: 1px solid #000000;"><span style="color: #000000;">&nbsp;17-Mar-2026</span></td> </tr> <tr style="height: 89px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">LOVD</span></p> </td> <td style="border: 1px solid #000000; padding: 4px; height: 89px;"> <p style="text-align: center; font-weight: normal;"><span style="color: #000000;">&nbsp;19-Jan-2026</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">&nbsp;17-Mar-2026</span></p> </td> </tr> <tr style="height: 89px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">OncoKB</span></p> </td> <td style="border: 1px solid #000000; padding: 4px; height: 89px;"> <p style="text-align: center; font-weight: normal;"><span style="color: #000000;">v5.4</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">v6.1</span></p> </td> </tr> <tr style="height: 89px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">cBioPortal</span></p> </td> <td style="border: 1px solid #000000; padding: 4px; height: 89px;"> <p style="text-align: center; font-weight: normal;"><span style="color: #000000;">06-Jun-2023</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">07-Mar-2026</span></p> </td> </tr> <tr style="height: 89px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">ClinVar</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89px;" rowspan="2"> <p style="text-align: center;"><span style="color: #000000;">07-Feb-2026</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89px; text-align: center;" rowspan="2"><span style="color: #000000;">07-Mar-2026</span></td> </tr> <tr style="height: 89px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">ClinVar CNVs</span></p> </td> </tr> <tr style="height: 89px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">ClinGen</span></p> </td> <td style="border: 1px solid #000000; padding: 4px; height: 89px;" rowspan="5"> <p style="text-align: center;"><span style="color: #000000;">07-Feb-2026</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89px;" rowspan="5"> <p style="text-align: center;"><span style="color: #000000;">07-Mar-2026</span></p> </td> </tr> <tr style="height: 89px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">ClinGen CNVs</span></p> </td> </tr> <tr style="height: 89px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">ClinGen Disease Validity</span></p> </td> </tr> <tr style="height: 89px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">ClinGen Regions</span></p> </td> </tr> <tr style="height: 89px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">ClinGen Variants</span></p> </td> </tr> <tr style="height: 89px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89px; text-align: center;"> <p><span style="color: #000000;">PharmGKB</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">07-Feb-2026</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89px; text-align: center;"><span style="color: #000000;">07-Mar-2026</span></td> </tr> <tr style="height: 89px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89px; text-align: center;"> <p><span style="color: #000000;">DECIPHER</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">07-Feb-2026</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89px; text-align: center;"><span style="color: #000000;">07-Mar-2026</span></td> </tr> <tr style="height: 89px;"> <td style="border: 1px solid #000000; padding: 4px; text-align: center; height: 89px;"> <p><span style="color: #000000;">dbNSFP</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">5.2</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; text-align: center; height: 89px;"><span style="color: #000000;">5.3.1</span></td> </tr> <tr style="height: 89px;"> <td style="border: 1px solid #000000; padding: 4px; text-align: center; height: 89px;"> <p><span style="color: #000000;">dbNSFP genes</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">5.2</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; text-align: center; height: 89px;"><span style="color: #000000;">5.3</span></td> </tr> </tbody> </table> <p>&nbsp;</p> <p>&nbsp;</p> <p><span style="color: #000000;">Version 13.15.0&nbsp;of VarSome, <a href="https://landing.varsome.com/varsome-api">VarSome API</a>, and <a href="https://landing.varsome.com/varsome-clinical">VarSome Clinical</a> will be&nbsp;released on 14 March 2026.</span></p> <h1 style="font-size: 20px;"><span style="color: #000000;">Summary of Key New Features</span></h1> <ul> <li><span style="color: #2ca591;"><a href="#fusions" style="color: #2ca591;">RNA fusion annotation from TSV and CSV files</a></span></li> <li><span style="color: #2ca591;"><a href="#splicevar" style="color: #2ca591;">Integration of SpliceVarDB</a></span></li> <li><span style="color: #2ca591;"><a href="#svs-overlap" style="color: #2ca591;">Structural Variant interpretation enhanced with overlap percentage against known SV datasets</a></span></li> <li><span style="color: #2ca591;"><a href="#oncokb" style="color: #2ca591;">New OncoKB<span style="font-size: 16px; color: #2ca591;">™</span>-based filters for oncogenicity, function, and levels of evidence</a></span></li> <li><a href="#oncotree"><span style="color: #2ca591;">Improved tumor type matching using OncoTree ontology</span></a><br><br></li> </ul> <p style="font-size: 16px;"><span style="color: #000000;"><span style="color: #000000;">Version 13.15.1.1 of <a href="https://landing.varsome.com/varsome-clinical">VarSome Clinical</a> was released on 16 April 2026.</span></span></p> <h1 style="font-size: 20px;"><span style="color: #000000;">Summary of Key New Features</span></h1> <ul> <li style="font-size: 16px;"> <p><span style="color: #000000;"><span style="color: #000000;">Fixed issues in somatic classification and sample display, and improving overall result reliability.</span></span></p> </li> </ul> <p style="font-size: 16px;">&nbsp;</p> <p style="font-size: 16px;"><span style="color: #000000;"><span style="color: #000000;">Version 13.15.1.0&nbsp;of VarSome, <a href="https://landing.varsome.com/varsome-api">VarSome API</a>, and <a href="https://landing.varsome.com/varsome-clinical">VarSome Clinical</a> was released on 26 March 2026.</span></span></p> <h1 style="font-size: 20px;"><span style="color: #000000;">Summary of Key New Features</span></h1> <ul> <li style="color: #1d1c1d;">Resolved an issue affecting access to CNV results for assigned samples, along with minor inconsistencies in roles and permissions.</li> <li style="color: #1d1c1d;">Fixed an edge case where the PP5 rule could be incorrectly triggered by somatic evidence in germline variant classification.</li> <li style="color: #1d1c1d;">General UI and UX improvements, along with minor bug fixes.</li> <li style="font-size: 16px;"><span style="color: #000000;">20 updated databases</span> (<a href="https://varsome.com/datasources/">full list of databases</a>).</li> </ul> <table style="border-collapse: collapse; table-layout: fixed; margin-left: auto; margin-right: auto; border: 1px solid #99acc2; width: 81%;"> <colgroup> <col style="width: 45.0508%;"> <col style="width: 27.3088%;"> <col style="width: 27.6567%;"> </colgroup> <tbody> <tr style="height: 71.5938px;"> <th style="height: 71.5938px; border-style: solid; text-align: center; background-color: #9fc5e8; border-color: #000000;"> <p><strong>Database </strong></p> </th> <th style="height: 71.5938px; border-style: solid; text-align: center; background-color: #9fc5e8; border-color: #000000;"> <p><strong>Old version </strong></p> </th> <th style="height: 71.5938px; border-style: solid; text-align: center; background-color: #9fc5e8; border-color: #000000;"> <p><strong>New version </strong></p> </th> </tr> <tr style="height: 89px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">CPIC</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">07-Jan-2026</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; text-align: center; height: 89px;"><span style="color: #000000;">07-Mar-2026</span></td> </tr> <tr style="height: 89px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">AACT</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">07-Feb-2026</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89px; text-align: center;"><span style="color: #000000;">07-Mar-2026</span></td> </tr> <tr style="height: 89px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">GWAS</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">07-Feb-2026</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89px; text-align: center;"><span style="color: #000000;">07-Mar-2026</span></td> </tr> <tr style="height: 89px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">gene2phenotype</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">07-Feb-2026</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89px; text-align: center;"><span style="color: #000000;">07-Mar-2026</span></td> </tr> <tr style="height: 89px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">CKB</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">14-Mar-2026</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; text-align: center; height: 89px;"><span style="color: #000000;">17-Mar-2026</span></td> </tr> <tr style="height: 89px;"> <td style="padding: 4px; height: 89px; border: 1px solid #000000;"> <p style="text-align: center;"><span style="color: #000000;">OMIM®</span></p> </td> <td style="padding: 4px; height: 89px; border: 1px solid #000000;"> <p style="text-align: center;"><span style="color: #000000;">&nbsp;19-Jan-2026</span></p> </td> <td style="text-align: center; padding: 4px; height: 89px; border: 1px solid #000000;"><span style="color: #000000;">&nbsp;17-Mar-2026</span></td> </tr> <tr style="height: 89px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">LOVD</span></p> </td> <td style="border: 1px solid #000000; padding: 4px; height: 89px;"> <p style="text-align: center; font-weight: normal;"><span style="color: #000000;">&nbsp;19-Jan-2026</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">&nbsp;17-Mar-2026</span></p> </td> </tr> <tr style="height: 89px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">OncoKB</span></p> </td> <td style="border: 1px solid #000000; padding: 4px; height: 89px;"> <p style="text-align: center; font-weight: normal;"><span style="color: #000000;">v5.4</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">v6.1</span></p> </td> </tr> <tr style="height: 89px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">cBioPortal</span></p> </td> <td style="border: 1px solid #000000; padding: 4px; height: 89px;"> <p style="text-align: center; font-weight: normal;"><span style="color: #000000;">06-Jun-2023</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">07-Mar-2026</span></p> </td> </tr> <tr style="height: 89px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">ClinVar</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89px;" rowspan="2"> <p style="text-align: center;"><span style="color: #000000;">07-Feb-2026</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89px; text-align: center;" rowspan="2"><span style="color: #000000;">07-Mar-2026</span></td> </tr> <tr style="height: 89px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">ClinVar CNVs</span></p> </td> </tr> <tr style="height: 89px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">ClinGen</span></p> </td> <td style="border: 1px solid #000000; padding: 4px; height: 89px;" rowspan="5"> <p style="text-align: center;"><span style="color: #000000;">07-Feb-2026</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89px;" rowspan="5"> <p style="text-align: center;"><span style="color: #000000;">07-Mar-2026</span></p> </td> </tr> <tr style="height: 89px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">ClinGen CNVs</span></p> </td> </tr> <tr style="height: 89px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">ClinGen Disease Validity</span></p> </td> </tr> <tr style="height: 89px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">ClinGen Regions</span></p> </td> </tr> <tr style="height: 89px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">ClinGen Variants</span></p> </td> </tr> <tr style="height: 89px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89px; text-align: center;"> <p><span style="color: #000000;">PharmGKB</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">07-Feb-2026</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89px; text-align: center;"><span style="color: #000000;">07-Mar-2026</span></td> </tr> <tr style="height: 89px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89px; text-align: center;"> <p><span style="color: #000000;">DECIPHER</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">07-Feb-2026</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89px; text-align: center;"><span style="color: #000000;">07-Mar-2026</span></td> </tr> <tr style="height: 89px;"> <td style="border: 1px solid #000000; padding: 4px; text-align: center; height: 89px;"> <p><span style="color: #000000;">dbNSFP</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">5.2</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; text-align: center; height: 89px;"><span style="color: #000000;">5.3.1</span></td> </tr> <tr style="height: 89px;"> <td style="border: 1px solid #000000; padding: 4px; text-align: center; height: 89px;"> <p><span style="color: #000000;">dbNSFP genes</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">5.2</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; text-align: center; height: 89px;"><span style="color: #000000;">5.3</span></td> </tr> </tbody> </table> <p>&nbsp;</p> <p>&nbsp;</p> <p><span style="color: #000000;">Version 13.15.0&nbsp;of VarSome, <a href="https://landing.varsome.com/varsome-api">VarSome API</a>, and <a href="https://landing.varsome.com/varsome-clinical">VarSome Clinical</a> will be&nbsp;released on 14 March 2026.</span></p> <h1 style="font-size: 20px;"><span style="color: #000000;">Summary of Key New Features</span></h1> <ul> <li><span style="color: #2ca591;"><a href="#fusions" style="color: #2ca591;">RNA fusion annotation from TSV and CSV files</a></span></li> <li><span style="color: #2ca591;"><a href="#splicevar" style="color: #2ca591;">Integration of SpliceVarDB</a></span></li> <li><span style="color: #2ca591;"><a href="#svs-overlap" style="color: #2ca591;">Structural Variant interpretation enhanced with overlap percentage against known SV datasets</a></span></li> <li><span style="color: #2ca591;"><a href="#oncokb" style="color: #2ca591;">New OncoKB<span style="font-size: 16px; color: #2ca591;">™</span>-based filters for oncogenicity, function, and levels of evidence</a></span></li> <li><a href="#oncotree"><span style="color: #2ca591;">Improved tumor type matching using OncoTree ontology</span></a><br><br></li> </ul> <img src="https://track.hubspot.com/__ptq.gif?a=4384097&amp;k=14&amp;r=https%3A%2F%2Fupdates.varsome.com%2Fen%2Fvarsome-v.13.15&amp;bu=https%253A%252F%252Fupdates.varsome.com%252Fen&amp;bvt=rss" alt="" width="1" height="1" style="min-height:1px!important;width:1px!important;border-width:0!important;margin-top:0!important;margin-bottom:0!important;margin-right:0!important;margin-left:0!important;padding-top:0!important;padding-bottom:0!important;padding-right:0!important;padding-left:0!important; "> Platform Updates VarSome API VarSome Clinical VarSome.com Premium Release Thu, 12 Mar 2026 14:56:56 GMT xanthippi.papakonstanti@saphetor.com (Xanthippi Papakonstanti) https://updates.varsome.com/en/varsome-v.13.15 2026-03-12T14:56:56Z VarSome API Update - v. 13.14.1 https://updates.varsome.com/en/varsome-api-update-v.-13.14.1 <p><span style="color: #000000;">On <span style="font-weight: bold;">6 </span><strong>March 2026</strong> we will be releasing the Q1 API changes for the VarSome API (</span><a href="http://stable-api.varsome.com/"><span>stable-api.varsome.com</span></a><span style="color: #000000;">).</span></p> <p><span style="color: #000000;">On <span style="font-weight: bold;">6 </span><strong>March 2026</strong> we will be releasing the Q1 API changes for the VarSome API (</span><a href="http://stable-api.varsome.com/"><span>stable-api.varsome.com</span></a><span style="color: #000000;">).</span></p> <img src="https://track.hubspot.com/__ptq.gif?a=4384097&amp;k=14&amp;r=https%3A%2F%2Fupdates.varsome.com%2Fen%2Fvarsome-api-update-v.-13.14.1&amp;bu=https%253A%252F%252Fupdates.varsome.com%252Fen&amp;bvt=rss" alt="" width="1" height="1" style="min-height:1px!important;width:1px!important;border-width:0!important;margin-top:0!important;margin-bottom:0!important;margin-right:0!important;margin-left:0!important;padding-top:0!important;padding-bottom:0!important;padding-right:0!important;padding-left:0!important; "> VarSome API Release Thu, 26 Feb 2026 10:41:08 GMT xanthippi.papakonstanti@saphetor.com (Xanthippi Papakonstanti) https://updates.varsome.com/en/varsome-api-update-v.-13.14.1 2026-02-26T10:41:08Z VarSome, VarSome API, & VarSome Clinical v.13.14.3 https://updates.varsome.com/en/varsome-v.13.14 <p style="font-size: 16px;"><span style="color: #000000;">Version 13.14.3 of VarSome, <a href="https://landing.varsome.com/varsome-api">VarSome API</a>, and <a href="https://landing.varsome.com/varsome-clinical">VarSome Clinical</a> was released on 19 February</span><span style="color: #000000;">&nbsp;2026.</span></p> <h1 style="font-size: 20px;"><span style="color: #000000;">Summary of Key New Features</span></h1> <ul> <li style="font-size: 16px;"><span style="color: #000000;">This release includes minor bug fixes.</span></li> <li style="font-size: 16px;"><span style="color: #000000;">18 updated databases</span> (<a href="https://varsome.com/datasources/">full list of databases</a>).</li> </ul> <table style="border-collapse: collapse; table-layout: fixed; margin-left: auto; margin-right: auto; border: 1px solid #99acc2; width: 81%;"> <colgroup> <col style="width: 45.0874%;"> <col style="width: 27.3564%;"> <col style="width: 27.6097%;"> </colgroup> <tbody> <tr style="height: 71.5938px;"> <th style="height: 71.5938px; border-style: solid; text-align: center; background-color: #9fc5e8; border-color: #000000;"> <p><strong>Database </strong></p> </th> <th style="height: 71.5938px; border-style: solid; text-align: center; background-color: #9fc5e8; border-color: #000000;"> <p><strong>Old version </strong></p> </th> <th style="height: 71.5938px; border-style: solid; text-align: center; background-color: #9fc5e8; border-color: #000000;"> <p><strong>New version </strong></p> </th> </tr> <tr style="height: 89px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">AACT</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">07-Jan-2026</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89px; text-align: center;"><span style="color: #000000;">07-Feb-2026</span></td> </tr> <tr style="height: 89px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">GWAS</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">07-Jan-2026</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89px; text-align: center;"><span style="color: #000000;">07-Feb-2026</span></td> </tr> <tr style="height: 89px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">gene2phenotype</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">07-Jan-2026</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89px; text-align: center;"><span style="color: #000000;">07-Feb-2026</span></td> </tr> <tr style="height: 89px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">TP53 Germline</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">release 20</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; text-align: center; height: 89px;"><span style="color: #000000;">release 21</span></td> </tr> <tr style="height: 89px;"> <td style="padding: 4px; height: 89px; border: 1px solid #000000;"> <p style="text-align: center;"><span style="color: #000000;">TP53 Somatic</span></p> </td> <td style="padding: 4px; height: 89px; border: 1px solid #000000;"> <p style="text-align: center;"><span style="color: #000000;">release 20</span></p> </td> <td style="text-align: center; padding: 4px; height: 89px; border: 1px solid #000000;"><span style="color: #000000;">release 21</span></td> </tr> <tr style="height: 89px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">ClinVar</span></p> </td> <td style="border: 1px solid #000000; padding: 4px; height: 89px;" rowspan="2"> <p style="text-align: center;"><span style="color: #000000;">&nbsp;07-Jan-2026</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89px;" rowspan="2"> <p style="text-align: center;"><span style="color: #000000;">07-Feb-2026</span></p> </td> </tr> <tr style="height: 89px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">ClinVar CNVs</span></p> </td> </tr> <tr style="height: 89px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">dbVar</span></p> </td> <td style="border: 1px solid #000000; padding: 4px; height: 89px;"> <p style="text-align: center; font-weight: normal;"><span style="color: #000000;">07-Nov-2025</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">07-Feb-2026</span></p> </td> </tr> <tr style="height: 89px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">ClinGen</span></p> </td> <td style="border: 1px solid #000000; padding: 4px; height: 89px;" rowspan="5"> <p style="text-align: center;"><span style="color: #000000;">07-Jan-2026</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89px;" rowspan="5"> <p style="text-align: center;"><span style="color: #000000;">07-Feb-2026</span></p> </td> </tr> <tr style="height: 89px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">ClinGen CNVs</span></p> </td> </tr> <tr style="height: 89px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">ClinGen Disease Validity</span></p> </td> </tr> <tr style="height: 89px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">ClinGen Regions</span></p> </td> </tr> <tr style="height: 89px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">ClinGen Variants</span></p> </td> </tr> <tr style="height: 89px;"> <td style="border: 1px solid #000000; padding: 4px; text-align: center; height: 89px;"> <p><span style="color: #000000;">GHR</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">07-Jan-2026</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; text-align: center; height: 89px;"><span style="color: #000000;">07-Feb-2026</span></td> </tr> <tr style="height: 89px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89px; text-align: center;"> <p><span style="color: #000000;">PharmGKB</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">07-Jan-2026</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89px; text-align: center;"><span style="color: #000000;">07-Feb-2026</span></td> </tr> <tr style="height: 89px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89px; text-align: center;"> <p><span style="color: #000000;">DECIPHER</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">07-Jan-2026</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89px; text-align: center;"><span style="color: #000000;">07-Feb-2026</span></td> </tr> <tr style="height: 89px;"> <td style="border: 1px solid #000000; padding: 4px; text-align: center; height: 89px;"> <p><span style="color: #000000;">UniProt Regions</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">07-Nov-2025</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; text-align: center; height: 89px;"><span style="color: #000000;">07-Feb-2026</span></td> </tr> <tr style="height: 89px;"> <td style="border: 1px solid #000000; padding: 4px; text-align: center; height: 89px;"> <p><span style="color: #000000;">UniProt Variants</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">07-Jul-2025</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; text-align: center; height: 89px;"><span style="color: #000000;">07-Feb-2026</span></td> </tr> </tbody> </table> <p>&nbsp;</p> <p><span>Version 13.14.1 of VarSome, <a href="https://landing.varsome.com/varsome-api">VarSome API</a>, and <a href="https://landing.varsome.com/varsome-clinical">VarSome Clinical</a> was released on 29 January 2026.</span></p> <h1 style="font-size: 20px;"><span>Summary of Key New Features</span></h1> <ul> <li><span>This release addresses minor issues and introduces a warning when an assay is selected that is not supported by the chosen reference genome.</span></li> <li><span>18 updated databases</span> (<a href="https://varsome.com/datasources/">full list of databases</a>).</li> </ul> <table style="border-collapse: collapse; table-layout: fixed; margin-left: auto; margin-right: auto; border: 1px solid #99acc2; width: 81%;"> <colgroup> <col style="width: 45.1984%;"> <col style="width: 27.2588%;"> <col style="width: 27.4918%;"> </colgroup> <tbody> <tr style="height: 71.5938px;"> <th style="height: 71.5938px; border-style: solid; text-align: center; background-color: #9fc5e8; border-color: #000000;"> <p><strong>Database </strong></p> </th> <th style="height: 71.5938px; border-style: solid; text-align: center; background-color: #9fc5e8; border-color: #000000;"> <p><strong>Old version </strong></p> </th> <th style="height: 71.5938px; border-style: solid; text-align: center; background-color: #9fc5e8; border-color: #000000;"> <p><strong>New version </strong></p> </th> </tr> <tr style="height: 89.5px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89.5px;"> <p style="text-align: center;"><span style="color: #000000;">CPIC</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89.5px;"> <p style="text-align: center;"><span style="color: #000000;">07-Dec-2025</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89.5px;"> <p style="text-align: center;"><span style="color: #000000;">07-Jan-2026</span></p> </td> </tr> <tr style="height: 89.5px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89.5px;"> <p style="text-align: center;"><span style="color: #000000;">AACT</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89.5px;"> <p style="text-align: center;"><span style="color: #000000;">07-Dec-2025</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89.5px; text-align: center;"><span style="color: #000000;">07-Jan-2026</span></td> </tr> <tr style="height: 89.5px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89.5px;"> <p style="text-align: center;"><span style="color: #000000;">GWAS</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89.5px;"> <p style="text-align: center;"><span style="color: #000000;">07-Dec-2025</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89.5px; text-align: center;"><span style="color: #000000;">07-Jan-2026</span></td> </tr> <tr style="height: 89.5px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89.5px;"> <p style="text-align: center;"><span style="color: #000000;">gene2phenotype</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89.5px;"> <p style="text-align: center;"><span style="color: #000000;">07-Dec-2025</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89.5px; text-align: center;"><span style="color: #000000;">07-Jan-2026</span></td> </tr> <tr style="height: 89.5px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89.5px;"> <p style="text-align: center;"><span style="color: #000000;">CKB</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89.5px;"> <p style="text-align: center;"><span style="color: #000000;">08-Dec-2025</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89.5px; text-align: center;">19-Jan-2026</td> </tr> <tr style="height: 89.5px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89.5px;"> <p style="text-align: center;"><span style="color: #000000;">OMIM®</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89.5px;"> <p style="text-align: center;"><span style="color: #000000;">08-Dec-2025</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89.5px; text-align: center;">19-Jan-2026</td> </tr> <tr style="height: 89.5px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89.5px;"> <p style="text-align: center;"><span style="color: #000000;">LOVD</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89.5px;"> <p style="text-align: center;"><span style="color: #000000;">08-Dec-2025</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89.5px; text-align: center;">19-Jan-2026</td> </tr> <tr style="height: 89.5px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89.5px;"> <p style="text-align: center;"><span style="color: #000000;">ClinVar</span></p> </td> <td style="border: 1px solid #000000; padding: 4px; height: 179px;" rowspan="2"> <p style="text-align: center;"><span style="color: #000000;">&nbsp;</span><span style="color: #000000;">07-Dec-2025</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 179px;" rowspan="2"> <p style="text-align: center;"><span style="color: #000000;">07-Jan-2026</span></p> </td> </tr> <tr style="height: 89.5px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89.5px;"> <p style="text-align: center;"><span style="color: #000000;">ClinVar CNVs</span></p> </td> </tr> <tr style="height: 89.5px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89.5px;"> <p style="text-align: center;"><span style="color: #000000;">ClinGen</span></p> </td> <td style="border: 1px solid #000000; padding: 4px; height: 358.094px;" rowspan="4"> <p style="text-align: center;"><span style="color: #000000;">07-Dec-2025</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 358.094px;" rowspan="4"> <p style="text-align: center;"><span style="color: #000000;">07-Jan-2026</span></p> </td> </tr> <tr style="height: 89.5px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89.5px;"> <p style="text-align: center;"><span style="color: #000000;">ClinGen CNVs</span></p> </td> </tr> <tr style="height: 89.5px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89.5px;"> <p style="text-align: center;"><span style="color: #000000;">ClinGen Disease Validity</span></p> </td> </tr> <tr style="height: 89.5938px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89.5938px;"> <p style="text-align: center;"><span style="color: #000000;">ClinGen Regions</span></p> </td> </tr> <tr style="height: 89px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">ClinGen Variants</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">07-Dec-2025</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89px; text-align: center;"><span style="color: #000000;">07-Jan-2026</span></td> </tr> <tr style="height: 89px;"> <td style="border: 1px solid #000000; padding: 4px; text-align: center; height: 89px;"> <p><span style="color: #000000;">GHR</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">07-Nov-2025</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; text-align: center; height: 89px;">07-Jan-2026</td> </tr> <tr style="height: 89px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89px; text-align: center;"> <p><span style="color: #000000;">PharmGKB</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">07-Dec-2025</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89px; text-align: center;"><span style="color: #000000;">07-Jan-2026</span></td> </tr> <tr style="height: 89px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89px; text-align: center;"> <p><span style="color: #000000;">DECIPHER</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">07-Dec-2025</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89px; text-align: center;"><span style="color: #000000;">07-Jan-2026</span></td> </tr> <tr style="height: 89px;"> <td style="border: 1px solid #000000; padding: 4px; text-align: center; height: 89px;"> <p><span style="color: #000000;">CIViC</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">07-Oct-2025</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; text-align: center; height: 89px;"><span style="color: #000000;">19-Jan-2026</span></td> </tr> </tbody> </table> <p style="font-size: 16px;">&nbsp;</p> <p style="font-size: 16px;">&nbsp;</p> <p style="font-size: 16px;"><span style="color: #000000;"><span style="color: #000000;">Version 13.14.0 of VarSome, <a href="https://landing.varsome.com/varsome-api">VarSome API</a>, and <a href="https://landing.varsome.com/varsome-clinical">VarSome Clinical</a> was released on 24 January 2026.</span></span></p> <p>&nbsp;</p> <p><span style="color: #000000;"><span>This scheduled maintenance was focused on i</span>nternal infrastructure updates,<span>&nbsp;ensuring system stability and preparing the platform for upcoming improvements.</span></span><br></p> <p style="font-size: 16px;"><span style="color: #000000;">Version 13.14.3 of VarSome, <a href="https://landing.varsome.com/varsome-api">VarSome API</a>, and <a href="https://landing.varsome.com/varsome-clinical">VarSome Clinical</a> was released on 19 February</span><span style="color: #000000;">&nbsp;2026.</span></p> <h1 style="font-size: 20px;"><span style="color: #000000;">Summary of Key New Features</span></h1> <ul> <li style="font-size: 16px;"><span style="color: #000000;">This release includes minor bug fixes.</span></li> <li style="font-size: 16px;"><span style="color: #000000;">18 updated databases</span> (<a href="https://varsome.com/datasources/">full list of databases</a>).</li> </ul> <table style="border-collapse: collapse; table-layout: fixed; margin-left: auto; margin-right: auto; border: 1px solid #99acc2; width: 81%;"> <colgroup> <col style="width: 45.0874%;"> <col style="width: 27.3564%;"> <col style="width: 27.6097%;"> </colgroup> <tbody> <tr style="height: 71.5938px;"> <th style="height: 71.5938px; border-style: solid; text-align: center; background-color: #9fc5e8; border-color: #000000;"> <p><strong>Database </strong></p> </th> <th style="height: 71.5938px; border-style: solid; text-align: center; background-color: #9fc5e8; border-color: #000000;"> <p><strong>Old version </strong></p> </th> <th style="height: 71.5938px; border-style: solid; text-align: center; background-color: #9fc5e8; border-color: #000000;"> <p><strong>New version </strong></p> </th> </tr> <tr style="height: 89px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">AACT</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">07-Jan-2026</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89px; text-align: center;"><span style="color: #000000;">07-Feb-2026</span></td> </tr> <tr style="height: 89px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">GWAS</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">07-Jan-2026</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89px; text-align: center;"><span style="color: #000000;">07-Feb-2026</span></td> </tr> <tr style="height: 89px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">gene2phenotype</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">07-Jan-2026</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89px; text-align: center;"><span style="color: #000000;">07-Feb-2026</span></td> </tr> <tr style="height: 89px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">TP53 Germline</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">release 20</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; text-align: center; height: 89px;"><span style="color: #000000;">release 21</span></td> </tr> <tr style="height: 89px;"> <td style="padding: 4px; height: 89px; border: 1px solid #000000;"> <p style="text-align: center;"><span style="color: #000000;">TP53 Somatic</span></p> </td> <td style="padding: 4px; height: 89px; border: 1px solid #000000;"> <p style="text-align: center;"><span style="color: #000000;">release 20</span></p> </td> <td style="text-align: center; padding: 4px; height: 89px; border: 1px solid #000000;"><span style="color: #000000;">release 21</span></td> </tr> <tr style="height: 89px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">ClinVar</span></p> </td> <td style="border: 1px solid #000000; padding: 4px; height: 89px;" rowspan="2"> <p style="text-align: center;"><span style="color: #000000;">&nbsp;07-Jan-2026</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89px;" rowspan="2"> <p style="text-align: center;"><span style="color: #000000;">07-Feb-2026</span></p> </td> </tr> <tr style="height: 89px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">ClinVar CNVs</span></p> </td> </tr> <tr style="height: 89px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">dbVar</span></p> </td> <td style="border: 1px solid #000000; padding: 4px; height: 89px;"> <p style="text-align: center; font-weight: normal;"><span style="color: #000000;">07-Nov-2025</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">07-Feb-2026</span></p> </td> </tr> <tr style="height: 89px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">ClinGen</span></p> </td> <td style="border: 1px solid #000000; padding: 4px; height: 89px;" rowspan="5"> <p style="text-align: center;"><span style="color: #000000;">07-Jan-2026</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89px;" rowspan="5"> <p style="text-align: center;"><span style="color: #000000;">07-Feb-2026</span></p> </td> </tr> <tr style="height: 89px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">ClinGen CNVs</span></p> </td> </tr> <tr style="height: 89px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">ClinGen Disease Validity</span></p> </td> </tr> <tr style="height: 89px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">ClinGen Regions</span></p> </td> </tr> <tr style="height: 89px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">ClinGen Variants</span></p> </td> </tr> <tr style="height: 89px;"> <td style="border: 1px solid #000000; padding: 4px; text-align: center; height: 89px;"> <p><span style="color: #000000;">GHR</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">07-Jan-2026</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; text-align: center; height: 89px;"><span style="color: #000000;">07-Feb-2026</span></td> </tr> <tr style="height: 89px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89px; text-align: center;"> <p><span style="color: #000000;">PharmGKB</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">07-Jan-2026</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89px; text-align: center;"><span style="color: #000000;">07-Feb-2026</span></td> </tr> <tr style="height: 89px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89px; text-align: center;"> <p><span style="color: #000000;">DECIPHER</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">07-Jan-2026</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89px; text-align: center;"><span style="color: #000000;">07-Feb-2026</span></td> </tr> <tr style="height: 89px;"> <td style="border: 1px solid #000000; padding: 4px; text-align: center; height: 89px;"> <p><span style="color: #000000;">UniProt Regions</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">07-Nov-2025</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; text-align: center; height: 89px;"><span style="color: #000000;">07-Feb-2026</span></td> </tr> <tr style="height: 89px;"> <td style="border: 1px solid #000000; padding: 4px; text-align: center; height: 89px;"> <p><span style="color: #000000;">UniProt Variants</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">07-Jul-2025</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; text-align: center; height: 89px;"><span style="color: #000000;">07-Feb-2026</span></td> </tr> </tbody> </table> <p>&nbsp;</p> <p><span>Version 13.14.1 of VarSome, <a href="https://landing.varsome.com/varsome-api">VarSome API</a>, and <a href="https://landing.varsome.com/varsome-clinical">VarSome Clinical</a> was released on 29 January 2026.</span></p> <h1 style="font-size: 20px;"><span>Summary of Key New Features</span></h1> <ul> <li><span>This release addresses minor issues and introduces a warning when an assay is selected that is not supported by the chosen reference genome.</span></li> <li><span>18 updated databases</span> (<a href="https://varsome.com/datasources/">full list of databases</a>).</li> </ul> <table style="border-collapse: collapse; table-layout: fixed; margin-left: auto; margin-right: auto; border: 1px solid #99acc2; width: 81%;"> <colgroup> <col style="width: 45.1984%;"> <col style="width: 27.2588%;"> <col style="width: 27.4918%;"> </colgroup> <tbody> <tr style="height: 71.5938px;"> <th style="height: 71.5938px; border-style: solid; text-align: center; background-color: #9fc5e8; border-color: #000000;"> <p><strong>Database </strong></p> </th> <th style="height: 71.5938px; border-style: solid; text-align: center; background-color: #9fc5e8; border-color: #000000;"> <p><strong>Old version </strong></p> </th> <th style="height: 71.5938px; border-style: solid; text-align: center; background-color: #9fc5e8; border-color: #000000;"> <p><strong>New version </strong></p> </th> </tr> <tr style="height: 89.5px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89.5px;"> <p style="text-align: center;"><span style="color: #000000;">CPIC</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89.5px;"> <p style="text-align: center;"><span style="color: #000000;">07-Dec-2025</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89.5px;"> <p style="text-align: center;"><span style="color: #000000;">07-Jan-2026</span></p> </td> </tr> <tr style="height: 89.5px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89.5px;"> <p style="text-align: center;"><span style="color: #000000;">AACT</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89.5px;"> <p style="text-align: center;"><span style="color: #000000;">07-Dec-2025</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89.5px; text-align: center;"><span style="color: #000000;">07-Jan-2026</span></td> </tr> <tr style="height: 89.5px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89.5px;"> <p style="text-align: center;"><span style="color: #000000;">GWAS</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89.5px;"> <p style="text-align: center;"><span style="color: #000000;">07-Dec-2025</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89.5px; text-align: center;"><span style="color: #000000;">07-Jan-2026</span></td> </tr> <tr style="height: 89.5px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89.5px;"> <p style="text-align: center;"><span style="color: #000000;">gene2phenotype</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89.5px;"> <p style="text-align: center;"><span style="color: #000000;">07-Dec-2025</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89.5px; text-align: center;"><span style="color: #000000;">07-Jan-2026</span></td> </tr> <tr style="height: 89.5px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89.5px;"> <p style="text-align: center;"><span style="color: #000000;">CKB</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89.5px;"> <p style="text-align: center;"><span style="color: #000000;">08-Dec-2025</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89.5px; text-align: center;">19-Jan-2026</td> </tr> <tr style="height: 89.5px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89.5px;"> <p style="text-align: center;"><span style="color: #000000;">OMIM®</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89.5px;"> <p style="text-align: center;"><span style="color: #000000;">08-Dec-2025</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89.5px; text-align: center;">19-Jan-2026</td> </tr> <tr style="height: 89.5px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89.5px;"> <p style="text-align: center;"><span style="color: #000000;">LOVD</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89.5px;"> <p style="text-align: center;"><span style="color: #000000;">08-Dec-2025</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89.5px; text-align: center;">19-Jan-2026</td> </tr> <tr style="height: 89.5px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89.5px;"> <p style="text-align: center;"><span style="color: #000000;">ClinVar</span></p> </td> <td style="border: 1px solid #000000; padding: 4px; height: 179px;" rowspan="2"> <p style="text-align: center;"><span style="color: #000000;">&nbsp;</span><span style="color: #000000;">07-Dec-2025</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 179px;" rowspan="2"> <p style="text-align: center;"><span style="color: #000000;">07-Jan-2026</span></p> </td> </tr> <tr style="height: 89.5px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89.5px;"> <p style="text-align: center;"><span style="color: #000000;">ClinVar CNVs</span></p> </td> </tr> <tr style="height: 89.5px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89.5px;"> <p style="text-align: center;"><span style="color: #000000;">ClinGen</span></p> </td> <td style="border: 1px solid #000000; padding: 4px; height: 358.094px;" rowspan="4"> <p style="text-align: center;"><span style="color: #000000;">07-Dec-2025</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 358.094px;" rowspan="4"> <p style="text-align: center;"><span style="color: #000000;">07-Jan-2026</span></p> </td> </tr> <tr style="height: 89.5px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89.5px;"> <p style="text-align: center;"><span style="color: #000000;">ClinGen CNVs</span></p> </td> </tr> <tr style="height: 89.5px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89.5px;"> <p style="text-align: center;"><span style="color: #000000;">ClinGen Disease Validity</span></p> </td> </tr> <tr style="height: 89.5938px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89.5938px;"> <p style="text-align: center;"><span style="color: #000000;">ClinGen Regions</span></p> </td> </tr> <tr style="height: 89px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">ClinGen Variants</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">07-Dec-2025</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89px; text-align: center;"><span style="color: #000000;">07-Jan-2026</span></td> </tr> <tr style="height: 89px;"> <td style="border: 1px solid #000000; padding: 4px; text-align: center; height: 89px;"> <p><span style="color: #000000;">GHR</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">07-Nov-2025</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; text-align: center; height: 89px;">07-Jan-2026</td> </tr> <tr style="height: 89px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89px; text-align: center;"> <p><span style="color: #000000;">PharmGKB</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">07-Dec-2025</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89px; text-align: center;"><span style="color: #000000;">07-Jan-2026</span></td> </tr> <tr style="height: 89px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89px; text-align: center;"> <p><span style="color: #000000;">DECIPHER</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">07-Dec-2025</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89px; text-align: center;"><span style="color: #000000;">07-Jan-2026</span></td> </tr> <tr style="height: 89px;"> <td style="border: 1px solid #000000; padding: 4px; text-align: center; height: 89px;"> <p><span style="color: #000000;">CIViC</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89px;"> <p style="text-align: center;"><span style="color: #000000;">07-Oct-2025</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; text-align: center; height: 89px;"><span style="color: #000000;">19-Jan-2026</span></td> </tr> </tbody> </table> <p style="font-size: 16px;">&nbsp;</p> <p style="font-size: 16px;">&nbsp;</p> <p style="font-size: 16px;"><span style="color: #000000;"><span style="color: #000000;">Version 13.14.0 of VarSome, <a href="https://landing.varsome.com/varsome-api">VarSome API</a>, and <a href="https://landing.varsome.com/varsome-clinical">VarSome Clinical</a> was released on 24 January 2026.</span></span></p> <p>&nbsp;</p> <p><span style="color: #000000;"><span>This scheduled maintenance was focused on i</span>nternal infrastructure updates,<span>&nbsp;ensuring system stability and preparing the platform for upcoming improvements.</span></span><br></p> <img src="https://track.hubspot.com/__ptq.gif?a=4384097&amp;k=14&amp;r=https%3A%2F%2Fupdates.varsome.com%2Fen%2Fvarsome-v.13.14&amp;bu=https%253A%252F%252Fupdates.varsome.com%252Fen&amp;bvt=rss" alt="" width="1" height="1" style="min-height:1px!important;width:1px!important;border-width:0!important;margin-top:0!important;margin-bottom:0!important;margin-right:0!important;margin-left:0!important;padding-top:0!important;padding-bottom:0!important;padding-right:0!important;padding-left:0!important; "> Platform Updates VarSome API VarSome Clinical VarSome.com Premium Release Sat, 24 Jan 2026 10:00:00 GMT xanthippi.papakonstanti@saphetor.com (Xanthippi Papakonstanti) https://updates.varsome.com/en/varsome-v.13.14 2026-01-24T10:00:00Z VarSome, VarSome API, & VarSome Clinical v.13.13.1 https://updates.varsome.com/en/varsome-v.13.13 <p style="font-size: 16px;"><span style="color: #000000;"><span style="color: #000000;">Version 13.13.1 of VarSome, <a href="https://landing.varsome.com/varsome-api">VarSome API</a>, and <a href="https://landing.varsome.com/varsome-clinical">VarSome Clinical</a> was released on 18 December 2025.</span></span></p> <h1 style="font-size: 20px;"><span style="color: #000000;">Summary of Key New Features</span></h1> <ul> <li style="font-size: 16px;"><span style="color: #000000;">17 updated databases</span> (<a href="https://varsome.com/datasources/">full list of databases</a>).</li> </ul> <table style="border-collapse: collapse; table-layout: fixed; margin-left: auto; margin-right: auto; border: 1px solid #99acc2; width: 81.9972%; height: 1593.58px;"> <colgroup> <col style="width: 45.189%;"> <col style="width: 27.1478%;"> <col style="width: 27.4914%;"> </colgroup> <tbody> <tr style="height: 71.5938px;"> <th style="height: 71.5938px; border-style: solid; text-align: center; background-color: #9fc5e8; border-color: #000000;"> <p><strong>Database </strong></p> </th> <th style="height: 71.5938px; border-style: solid; text-align: center; background-color: #9fc5e8; border-color: #000000;"> <p><strong>Old version </strong></p> </th> <th style="height: 71.5938px; border-style: solid; text-align: center; background-color: #9fc5e8; border-color: #000000;"> <p><strong>New version </strong></p> </th> </tr> <tr style="height: 89.5px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89.5px;"> <p style="text-align: center;"><span style="color: #000000;">CPIC</span></p> </td> <td style="border: 1px solid #000000; padding: 4px; height: 89.5px;"> <p style="text-align: center;"><span style="color: #000000;">07-Nov-2025</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89.5px;"> <p style="text-align: center;"><span style="color: #000000;">07-Dec-2025</span></p> </td> </tr> <tr style="height: 89.5px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89.5px;"> <p style="text-align: center;"><span style="color: #000000;">AACT</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89.5px;"> <p style="text-align: center;"><span style="color: #000000;">07-Nov-2025</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89.5px;"> <p style="text-align: center;"><span style="color: #000000;">07-Dec-2025</span></p> </td> </tr> <tr style="height: 89.5px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89.5px;"> <p style="text-align: center;"><span style="color: #000000;">GWAS</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89.5px;"> <p style="text-align: center;"><span style="color: #000000;">07-Nov-2025</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89.5px;"> <p style="text-align: center;"><span style="color: #000000;">07-Dec-2025</span></p> </td> </tr> <tr style="height: 89.5px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89.5px;"> <p style="text-align: center;"><span style="color: #000000;">gene2phenotype</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89.5px;"> <p style="text-align: center;"><span style="color: #000000;">07-Nov-2025</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89.5px;"> <p style="text-align: center;"><span style="color: #000000;">07-Dec-2025</span></p> </td> </tr> <tr style="height: 89.5px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89.5px;"> <p style="text-align: center;"><span style="color: #000000;">CKB</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89.5px;"> <p style="text-align: center;"><span style="color: #000000;">07-Oct-2025</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89.5px;"> <p style="text-align: center;"><span style="color: #000000;">08-Dec-2025</span></p> </td> </tr> <tr style="height: 89.5px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89.5px;"> <p style="text-align: center;"><span style="color: #000000;">OMIM®</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89.5px;"> <p style="text-align: center;"><span style="color: #000000;">16-Nov-2025</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89.5px;"> <p style="text-align: center;"><span style="color: #000000;">08-Dec-2025</span></p> </td> </tr> <tr style="height: 89.5px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89.5px;"> <p style="text-align: center;"><span style="color: #000000;">LOVD</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89.5px;"> <p style="text-align: center;"><span style="color: #000000;">16-Nov-2025</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89.5px;"> <p style="text-align: center;"><span style="color: #000000;">08-Dec-2025</span></p> </td> </tr> <tr style="height: 89.5px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89.5px;"> <p style="text-align: center;"><span style="color: #000000;">OncoKB</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89.5px;"> <p style="text-align: center;"><span style="color: #000000;">v5.3</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89.5px;"> <p style="text-align: center;"><span style="color: #000000;">v5.4</span></p> </td> </tr> <tr style="height: 89.5px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89.5px;"> <p style="text-align: center;"><span style="color: #000000;">ClinVar</span></p> </td> <td style="border: 1px solid #000000; padding: 4px; height: 179.016px;" rowspan="2"> <p style="text-align: center;"><span style="color: #000000;">&nbsp;</span><span style="color: #000000;">07-Nov-2025</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 179.016px;" rowspan="2"> <p style="text-align: center;"><span style="color: #000000;">&nbsp;</span><span style="color: #000000;">07-Dec-2025</span></p> </td> </tr> <tr style="height: 89.5156px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89.5156px;"> <p style="text-align: center;"><span style="color: #000000;">ClinVar CNVs</span></p> </td> </tr> <tr style="height: 89.5px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89.5px;"> <p style="text-align: center;"><span style="color: #000000;">ClinGen</span></p> </td> <td style="border: 1px solid #000000; padding: 4px; height: 358.094px;" rowspan="4"> <p style="text-align: center;"><span style="color: #000000;">07-Nov-2025</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 358.094px;" rowspan="4"> <p style="text-align: center;"><span style="color: #000000;">07-Dec-2025</span></p> </td> </tr> <tr style="height: 89.5px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89.5px;"> <p style="text-align: center;"><span style="color: #000000;">ClinGen CNVs</span></p> </td> </tr> <tr style="height: 89.5px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89.5px;"> <p style="text-align: center;"><span style="color: #000000;">ClinGen Disease Validity</span></p> </td> </tr> <tr style="height: 89.5938px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89.5938px;"> <p style="text-align: center;"><span style="color: #000000;">ClinGen Regions</span></p> </td> </tr> <tr style="height: 89.5px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89.5px;"> <p style="text-align: center;"><span style="color: #000000;">ClinGen Variants</span></p> </td> <td style="border: 1px solid #000000; padding: 4px; height: 89.5px;"> <p style="text-align: center;"><span style="color: #000000;">07-Nov-2025</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89.5px;"> <p style="text-align: center;"><span style="color: #000000;">07-Dec-2025</span></p> </td> </tr> <tr style="height: 89.5px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89.5px; text-align: center;"> <p><span style="color: #000000;">PharmGKB</span></p> </td> <td style="border: 1px solid #000000; padding: 4px; height: 89.5px;"> <p style="text-align: center;"><span style="color: #000000;">07-Nov-2025</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89.5px;"> <p style="text-align: center;"><span style="color: #000000;">07-Dec-2025</span></p> </td> </tr> <tr style="height: 89.875px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89.875px; text-align: center;"> <p><span style="color: #000000;">DECIPHER</span></p> </td> <td style="border: 1px solid #000000; padding: 4px; height: 89.5px;"> <p style="text-align: center;"><span style="color: #000000;">07-Nov-2025</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89.5px;"> <p style="text-align: center;"><span style="color: #000000;">07-Dec-2025</span></p> </td> </tr> </tbody> </table> <p style="font-size: 16px;">&nbsp;</p> <p style="font-size: 16px;"><span style="color: #000000;"><span style="color: #000000;">Version 13.13.0 of VarSome, <a href="https://landing.varsome.com/varsome-api">VarSome API</a>, and <a href="https://landing.varsome.com/varsome-clinical">VarSome Clinical</a> was released on 13 December 2025.</span></span></p> <p style="font-size: 16px;">&nbsp;</p> <h1 style="font-size: 20px;"><span style="color: #000000;">Summary of Key New Features</span></h1> <ul> <li><span style="color: #2ca591;"><a href="#cosmic" style="color: #2ca591;">Major expansion of COSMIC variant card with transcript-level and sample-level tables</a></span></li> <li><span style="color: #2ca591;"><a href="#group-roles" style="color: #2ca591;">Introduction of Group-based Roles &amp; Permissions (granular access control)</a></span></li> <li><span style="color: #2ca591;"><a href="#trio" style="color: #2ca591;">Enhanced Family Trio Recessive filter</a></span></li> <li><span style="color: #2ca591;"><a href="#ml-sentieon" style="color: #2ca591;">Optional ML-based Sentieon variant-calling pipeline available upon request</a></span></li> <li><span style="color: #2ca591;"><a href="#variant-table" style="color: #2ca591;">Spreadsheet export now preserves the Variant Table ordering</a></span><br><br></li> </ul> <p style="font-size: 16px;"><span style="color: #000000;"><span style="color: #000000;">Version 13.13.1 of VarSome, <a href="https://landing.varsome.com/varsome-api">VarSome API</a>, and <a href="https://landing.varsome.com/varsome-clinical">VarSome Clinical</a> was released on 18 December 2025.</span></span></p> <h1 style="font-size: 20px;"><span style="color: #000000;">Summary of Key New Features</span></h1> <ul> <li style="font-size: 16px;"><span style="color: #000000;">17 updated databases</span> (<a href="https://varsome.com/datasources/">full list of databases</a>).</li> </ul> <table style="border-collapse: collapse; table-layout: fixed; margin-left: auto; margin-right: auto; border: 1px solid #99acc2; width: 81.9972%; height: 1593.58px;"> <colgroup> <col style="width: 45.189%;"> <col style="width: 27.1478%;"> <col style="width: 27.4914%;"> </colgroup> <tbody> <tr style="height: 71.5938px;"> <th style="height: 71.5938px; border-style: solid; text-align: center; background-color: #9fc5e8; border-color: #000000;"> <p><strong>Database </strong></p> </th> <th style="height: 71.5938px; border-style: solid; text-align: center; background-color: #9fc5e8; border-color: #000000;"> <p><strong>Old version </strong></p> </th> <th style="height: 71.5938px; border-style: solid; text-align: center; background-color: #9fc5e8; border-color: #000000;"> <p><strong>New version </strong></p> </th> </tr> <tr style="height: 89.5px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89.5px;"> <p style="text-align: center;"><span style="color: #000000;">CPIC</span></p> </td> <td style="border: 1px solid #000000; padding: 4px; height: 89.5px;"> <p style="text-align: center;"><span style="color: #000000;">07-Nov-2025</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89.5px;"> <p style="text-align: center;"><span style="color: #000000;">07-Dec-2025</span></p> </td> </tr> <tr style="height: 89.5px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89.5px;"> <p style="text-align: center;"><span style="color: #000000;">AACT</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89.5px;"> <p style="text-align: center;"><span style="color: #000000;">07-Nov-2025</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89.5px;"> <p style="text-align: center;"><span style="color: #000000;">07-Dec-2025</span></p> </td> </tr> <tr style="height: 89.5px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89.5px;"> <p style="text-align: center;"><span style="color: #000000;">GWAS</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89.5px;"> <p style="text-align: center;"><span style="color: #000000;">07-Nov-2025</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89.5px;"> <p style="text-align: center;"><span style="color: #000000;">07-Dec-2025</span></p> </td> </tr> <tr style="height: 89.5px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89.5px;"> <p style="text-align: center;"><span style="color: #000000;">gene2phenotype</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89.5px;"> <p style="text-align: center;"><span style="color: #000000;">07-Nov-2025</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89.5px;"> <p style="text-align: center;"><span style="color: #000000;">07-Dec-2025</span></p> </td> </tr> <tr style="height: 89.5px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89.5px;"> <p style="text-align: center;"><span style="color: #000000;">CKB</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89.5px;"> <p style="text-align: center;"><span style="color: #000000;">07-Oct-2025</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89.5px;"> <p style="text-align: center;"><span style="color: #000000;">08-Dec-2025</span></p> </td> </tr> <tr style="height: 89.5px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89.5px;"> <p style="text-align: center;"><span style="color: #000000;">OMIM®</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89.5px;"> <p style="text-align: center;"><span style="color: #000000;">16-Nov-2025</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89.5px;"> <p style="text-align: center;"><span style="color: #000000;">08-Dec-2025</span></p> </td> </tr> <tr style="height: 89.5px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89.5px;"> <p style="text-align: center;"><span style="color: #000000;">LOVD</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89.5px;"> <p style="text-align: center;"><span style="color: #000000;">16-Nov-2025</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89.5px;"> <p style="text-align: center;"><span style="color: #000000;">08-Dec-2025</span></p> </td> </tr> <tr style="height: 89.5px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89.5px;"> <p style="text-align: center;"><span style="color: #000000;">OncoKB</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89.5px;"> <p style="text-align: center;"><span style="color: #000000;">v5.3</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89.5px;"> <p style="text-align: center;"><span style="color: #000000;">v5.4</span></p> </td> </tr> <tr style="height: 89.5px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89.5px;"> <p style="text-align: center;"><span style="color: #000000;">ClinVar</span></p> </td> <td style="border: 1px solid #000000; padding: 4px; height: 179.016px;" rowspan="2"> <p style="text-align: center;"><span style="color: #000000;">&nbsp;</span><span style="color: #000000;">07-Nov-2025</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 179.016px;" rowspan="2"> <p style="text-align: center;"><span style="color: #000000;">&nbsp;</span><span style="color: #000000;">07-Dec-2025</span></p> </td> </tr> <tr style="height: 89.5156px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89.5156px;"> <p style="text-align: center;"><span style="color: #000000;">ClinVar CNVs</span></p> </td> </tr> <tr style="height: 89.5px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89.5px;"> <p style="text-align: center;"><span style="color: #000000;">ClinGen</span></p> </td> <td style="border: 1px solid #000000; padding: 4px; height: 358.094px;" rowspan="4"> <p style="text-align: center;"><span style="color: #000000;">07-Nov-2025</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 358.094px;" rowspan="4"> <p style="text-align: center;"><span style="color: #000000;">07-Dec-2025</span></p> </td> </tr> <tr style="height: 89.5px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89.5px;"> <p style="text-align: center;"><span style="color: #000000;">ClinGen CNVs</span></p> </td> </tr> <tr style="height: 89.5px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89.5px;"> <p style="text-align: center;"><span style="color: #000000;">ClinGen Disease Validity</span></p> </td> </tr> <tr style="height: 89.5938px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89.5938px;"> <p style="text-align: center;"><span style="color: #000000;">ClinGen Regions</span></p> </td> </tr> <tr style="height: 89.5px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89.5px;"> <p style="text-align: center;"><span style="color: #000000;">ClinGen Variants</span></p> </td> <td style="border: 1px solid #000000; padding: 4px; height: 89.5px;"> <p style="text-align: center;"><span style="color: #000000;">07-Nov-2025</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89.5px;"> <p style="text-align: center;"><span style="color: #000000;">07-Dec-2025</span></p> </td> </tr> <tr style="height: 89.5px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89.5px; text-align: center;"> <p><span style="color: #000000;">PharmGKB</span></p> </td> <td style="border: 1px solid #000000; padding: 4px; height: 89.5px;"> <p style="text-align: center;"><span style="color: #000000;">07-Nov-2025</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89.5px;"> <p style="text-align: center;"><span style="color: #000000;">07-Dec-2025</span></p> </td> </tr> <tr style="height: 89.875px;"> <td style="border: 1px solid #000000; padding: 4px; height: 89.875px; text-align: center;"> <p><span style="color: #000000;">DECIPHER</span></p> </td> <td style="border: 1px solid #000000; padding: 4px; height: 89.5px;"> <p style="text-align: center;"><span style="color: #000000;">07-Nov-2025</span></p> </td> <td style="padding: 4px; border: 1px solid #000000; height: 89.5px;"> <p style="text-align: center;"><span style="color: #000000;">07-Dec-2025</span></p> </td> </tr> </tbody> </table> <p style="font-size: 16px;">&nbsp;</p> <p style="font-size: 16px;"><span style="color: #000000;"><span style="color: #000000;">Version 13.13.0 of VarSome, <a href="https://landing.varsome.com/varsome-api">VarSome API</a>, and <a href="https://landing.varsome.com/varsome-clinical">VarSome Clinical</a> was released on 13 December 2025.</span></span></p> <p style="font-size: 16px;">&nbsp;</p> <h1 style="font-size: 20px;"><span style="color: #000000;">Summary of Key New Features</span></h1> <ul> <li><span style="color: #2ca591;"><a href="#cosmic" style="color: #2ca591;">Major expansion of COSMIC variant card with transcript-level and sample-level tables</a></span></li> <li><span style="color: #2ca591;"><a href="#group-roles" style="color: #2ca591;">Introduction of Group-based Roles &amp; Permissions (granular access control)</a></span></li> <li><span style="color: #2ca591;"><a href="#trio" style="color: #2ca591;">Enhanced Family Trio Recessive filter</a></span></li> <li><span style="color: #2ca591;"><a href="#ml-sentieon" style="color: #2ca591;">Optional ML-based Sentieon variant-calling pipeline available upon request</a></span></li> <li><span style="color: #2ca591;"><a href="#variant-table" style="color: #2ca591;">Spreadsheet export now preserves the Variant Table ordering</a></span><br><br></li> </ul> <img src="https://track.hubspot.com/__ptq.gif?a=4384097&amp;k=14&amp;r=https%3A%2F%2Fupdates.varsome.com%2Fen%2Fvarsome-v.13.13&amp;bu=https%253A%252F%252Fupdates.varsome.com%252Fen&amp;bvt=rss" alt="" width="1" height="1" style="min-height:1px!important;width:1px!important;border-width:0!important;margin-top:0!important;margin-bottom:0!important;margin-right:0!important;margin-left:0!important;padding-top:0!important;padding-bottom:0!important;padding-right:0!important;padding-left:0!important; "> Platform Updates VarSome API VarSome Clinical VarSome.com Premium Release Mon, 08 Dec 2025 13:25:29 GMT xanthippi.papakonstanti@saphetor.com (Xanthippi Papakonstanti) https://updates.varsome.com/en/varsome-v.13.13 2025-12-08T13:25:29Z VarSome API Update - V. 13.12.2 https://updates.varsome.com/en/varsome-api-update-v.-13.12.2 <p><span style="color: #000000;">On <strong>5 December 2025</strong> we will be releasing the Q4 API changes for the VarSome API (</span><a href="http://stable-api.varsome.com/"><span>stable-api.varsome.com</span></a><span style="color: #000000;">).</span></p> <p><span style="color: #000000;">On <strong>5 December 2025</strong> we will be releasing the Q4 API changes for the VarSome API (</span><a href="http://stable-api.varsome.com/"><span>stable-api.varsome.com</span></a><span style="color: #000000;">).</span></p> <img src="https://track.hubspot.com/__ptq.gif?a=4384097&amp;k=14&amp;r=https%3A%2F%2Fupdates.varsome.com%2Fen%2Fvarsome-api-update-v.-13.12.2&amp;bu=https%253A%252F%252Fupdates.varsome.com%252Fen&amp;bvt=rss" alt="" width="1" height="1" style="min-height:1px!important;width:1px!important;border-width:0!important;margin-top:0!important;margin-bottom:0!important;margin-right:0!important;margin-left:0!important;padding-top:0!important;padding-bottom:0!important;padding-right:0!important;padding-left:0!important; "> VarSome API Release Thu, 13 Nov 2025 16:09:09 GMT xanthippi.papakonstanti@saphetor.com (Xanthippi Papakonstanti) https://updates.varsome.com/en/varsome-api-update-v.-13.12.2 2025-11-13T16:09:09Z VarSome, VarSome API, & VarSome Clinical v.13.12.2 https://updates.varsome.com/en/varsome-v.13.12.0 <p style="font-size: 16px;"><span style="color: #000000;"><span style="color: #000000;">Version 13.12.2 of VarSome, <a href="https://landing.varsome.com/varsome-api">VarSome API</a>, and <a href="https://landing.varsome.com/varsome-clinical">VarSome Clinical</a> was released on 27 November 2025.</span></span></p> <h1 style="font-size: 20px;"><span style="color: #000000;">Summary of Key New Features</span></h1> <ul> <li style="font-size: 16px;"><span style="color: #000000;">25 updated databases</span> (<a href="https://varsome.com/datasources/">full list of databases</a>).</li> </ul> <h1><span style="font-size: 20px; color: #000000;">Updated Databases</span></h1> <div> <div> <div> <div> <span>&nbsp;</span> <span></span> <table style="border-collapse: collapse; table-layout: fixed; margin-left: auto; margin-right: auto; border: 1px solid #99acc2; width: 81.9972%; height: 1595.98px;"> <colgroup> <col style="width: 45.189%;"> <col style="width: 27.1478%;"> <col style="width: 27.4914%;"> </colgroup> <tbody> <tr style="height: 55.9844px;"> <th style="height: 55.9844px; border-style: solid; text-align: center; background-color: #9fc5e8; border-color: #000000;"> <p><strong>Database </strong></p> </th> <th style="height: 55.9844px; border-style: solid; text-align: center; background-color: #9fc5e8; border-color: #000000;"> <p><strong>Old version </strong></p> </th> <th style="height: 55.9844px; border-style: solid; text-align: center; background-color: #9fc5e8; border-color: #000000;"> <p><strong>New version </strong></p> </th> </tr> <tr style="height: 70px;"> <td style="border: 1px solid #000000; padding: 4px;"> <p style="text-align: center;"><span style="color: #000000;">CPIC</span></p> </td> <td style="border: 1px solid #000000; padding: 4px;"> <p style="text-align: center;"><span style="color: #000000;">07-Mar-2025</span></p> </td> <td style="padding: 4px; border: 1px solid #000000;"> <p style="text-align: center;"><span style="color: #000000;">07-Nov-2025</span></p> </td> </tr> <tr style="height: 70px;"> <td style="border: 1px solid #000000; padding: 4px;"> <p style="text-align: center;"><span style="color: #000000;">AACT</span></p> </td> <td style="border: 1px solid #000000; padding: 4px;"> <p style="text-align: center;"><span style="color: #000000;">07-Oct-2025</span></p> </td> <td style="padding: 4px; border: 1px solid #000000;"> <p style="text-align: center;"><span style="color: #000000;">07-Nov-2025</span></p> </td> </tr> <tr style="height: 70px;"> <td style="border: 1px solid #000000; padding: 4px;"> <p style="text-align: center;"><span style="color: #000000;">GWAS</span></p> </td> <td style="border: 1px solid #000000; padding: 4px;"> <p style="text-align: center;"><span style="color: #000000;">07-Sep-2025</span></p> </td> <td style="padding: 4px; border: 1px solid #000000;"> <p style="text-align: center;"><span style="color: #000000;">07-Nov-2025</span></p> </td> </tr> <tr style="height: 70px;"> <td style="border: 1px solid #000000; padding: 4px;"> <p style="text-align: center;"><span style="color: #000000;">gene2phenotype</span></p> </td> <td style="border: 1px solid #000000; padding: 4px;"> <p style="text-align: center;"><span style="color: #000000;">07-Sep-2025</span></p> </td> <td style="padding: 4px; border: 1px solid #000000;"> <p style="text-align: center;"><span style="color: #000000;">07-Nov-2025</span></p> </td> </tr> <tr style="height: 70px;"> <td style="border: 1px solid #000000; padding: 4px;"> <p style="text-align: center;"><span style="color: #000000;">Ensembl</span></p> </td> <td style="border: 1px solid #000000; padding: 4px;"> <p style="text-align: center;"><span style="color: #000000;">113</span></p> </td> <td style="padding: 4px; border: 1px solid #000000;"> <p style="text-align: center;"><span style="color: #000000;">115</span></p> </td> </tr> <tr style="height: 70px;"> <td style="border: 1px solid #000000; padding: 4px;"> <p style="text-align: center;"><span style="color: #000000;">HGNC</span></p> </td> <td style="border: 1px solid #000000; padding: 4px;"> <p style="text-align: center;"><span style="color: #000000;">13-Feb-2025</span></p> </td> <td style="padding: 4px; border: 1px solid #000000;"> <p style="text-align: center;"><span style="color: #000000;">07-Nov-2025</span></p> </td> </tr> <tr style="height: 70px;"> <td style="border: 1px solid #000000; padding: 4px;"> <p style="text-align: center;"><span style="color: #000000;">OMIM®</span></p> </td> <td style="border: 1px solid #000000; padding: 4px;"> <p style="text-align: center;"><span style="color: #000000;">16-Sep-2025</span></p> </td> <td style="padding: 4px; border: 1px solid #000000;"> <p style="text-align: center;"><span style="color: #000000;">16-Nov-2025</span></p> </td> </tr> <tr style="height: 70px;"> <td style="border: 1px solid #000000; padding: 4px;"> <p style="text-align: center;"><span style="color: #000000;">LOVD</span></p> </td> <td style="border: 1px solid #000000; padding: 4px;"> <p style="text-align: center;"><span style="color: #000000;">16-Sep-2025</span></p> </td> <td style="padding: 4px; border: 1px solid #000000;"> <p style="text-align: center;"><span style="color: #000000;">16-Nov-2025</span></p> </td> </tr> <tr style="height: 70px;"> <td style="border: 1px solid #000000; padding: 4px;"> <p style="text-align: center;"><span style="color: #000000;">OncoKB</span></p> </td> <td style="border: 1px solid #000000; padding: 4px;"> <p style="text-align: center;"><span style="color: #000000;">v5.1</span></p> </td> <td style="padding: 4px; border: 1px solid #000000;"> <p style="text-align: center;"><span style="color: #000000;">v5.3</span></p> </td> </tr> <tr style="height: 70px;"> <td style="border: 1px solid #000000; padding: 4px;"> <p style="text-align: center;"><span style="color: #000000;">Mondo</span></p> </td> <td style="border: 1px solid #000000; padding: 4px;"> <p style="text-align: center;"><span style="color: #000000;">07-Feb-2025</span></p> </td> <td style="padding: 4px; border: 1px solid #000000;"> <p style="text-align: center;"><span style="color: #000000;">&nbsp;</span><span style="color: #000000;">07-Nov-2025</span></p> </td> </tr> <tr style="height: 70px;"> <td style="border: 1px solid #000000; padding: 4px;"> <p style="text-align: center;"><span style="color: #000000;">ClinVar</span></p> </td> <td style="border: 1px solid #000000; padding: 4px;" rowspan="2"> <p style="text-align: center;"><span style="color: #000000;">&nbsp;</span><span style="color: #000000;">07-Jul-2025</span></p> </td> <td style="padding: 4px; border: 1px solid #000000;" rowspan="2"> <p style="text-align: center;"><span style="color: #000000;">&nbsp;</span><span style="color: #000000;">07-Nov-2025</span></p> </td> </tr> <tr style="height: 70px;"> <td style="border: 1px solid #000000; padding: 4px;"> <p style="text-align: center;"><span style="color: #000000;">ClinVar CNVs</span></p> </td> </tr> <tr style="height: 70px;"> <td style="border: 1px solid #000000; padding: 4px;"> <p style="text-align: center;"><span style="color: #000000;">RefSeq</span></p> </td> <td style="border: 1px solid #000000; padding: 4px;"> <p style="text-align: center;"><span style="color: #000000;">228</span></p> </td> <td style="padding: 4px; border: 1px solid #000000;"> <p style="text-align: center;"><span style="color: #000000;">232</span></p> </td> </tr> <tr style="height: 70px;"> <td style="border: 1px solid #000000; padding: 4px;"> <p style="text-align: center;"><span style="color: #000000;">dbSNP</span></p> </td> <td style="border: 1px solid #000000; padding: 4px;"> <p style="text-align: center;"><span style="color: #000000;">build 156</span></p> </td> <td style="padding: 4px; border: 1px solid #000000;"> <p style="text-align: center;"><span style="color: #000000;">build 157</span></p> </td> </tr> <tr style="height: 70px;"> <td style="border: 1px solid #000000; padding: 4px;"> <p style="text-align: center;"><span style="color: #000000;">dbVar</span></p> </td> <td style="border: 1px solid #000000; padding: 4px;"> <p style="text-align: center;"><span style="color: #000000;">07-Jun-2025</span></p> </td> <td style="padding: 4px; border: 1px solid #000000;"> <p style="text-align: center;"><span style="color: #000000;">07-Nov-2025</span></p> </td> </tr> <tr style="height: 70px;"> <td style="border: 1px solid #000000; padding: 4px;"> <p style="text-align: center;"><span style="color: #000000;">ClinGen</span></p> </td> <td style="border: 1px solid #000000; padding: 4px;" rowspan="4"> <p style="text-align: center;"><span style="color: #000000;">07-Sep-2025</span></p> </td> <td style="padding: 4px; border: 1px solid #000000;" rowspan="4"> <p style="text-align: center;"><span style="color: #000000;">07-Nov-2025</span></p> </td> </tr> <tr style="height: 70px;"> <td style="border: 1px solid #000000; padding: 4px;"> <p style="text-align: center;"><span style="color: #000000;">ClinGen CNVs</span></p> </td> </tr> <tr style="height: 70px;"> <td style="border: 1px solid #000000; padding: 4px;"> <p style="text-align: center;"><span style="color: #000000;">ClinGen Disease Validity</span></p> </td> </tr> <tr style="height: 70px;"> <td style="border: 1px solid #000000; padding: 4px;"> <p style="text-align: center;"><span style="color: #000000;">ClinGen Regions</span></p> </td> </tr> <tr style="height: 70px;"> <td style="border: 1px solid #000000; padding: 4px;"> <p style="text-align: center;"><span style="color: #000000;">ClinGen Variants</span></p> </td> <td style="border: 1px solid #000000; padding: 4px;"> <p style="text-align: center;"><span style="color: #000000;">07-Sep-2025</span></p> </td> <td style="padding: 4px; border: 1px solid #000000;"> <p style="text-align: center;"><span style="color: #000000;">07-Nov-2025</span></p> </td> </tr> <tr style="height: 70px;"> <td style="border: 1px solid #000000; padding: 4px;"> <p style="text-align: center;"><span style="color: #000000;">GHR</span></p> </td> <td style="border: 1px solid #000000; padding: 4px;"> <p style="text-align: center;"><span style="color: #000000;">07-Sep-2025</span></p> </td> <td style="padding: 4px; border: 1px solid #000000;"> <p style="text-align: center;"><span style="color: #000000;">07-Nov-2025</span></p> </td> </tr> <tr style="height: 70px;"> <td style="border: 1px solid #000000; padding: 4px;"> <p style="text-align: center;"><span style="color: #000000;">PharmGKB</span></p> </td> <td style="border: 1px solid #000000; padding: 4px;"> <p style="text-align: center;"><span style="color: #000000;">07-Sep-2025</span></p> </td> <td style="padding: 4px; border: 1px solid #000000;"> <p style="text-align: center;"><span style="color: #000000;">07-Nov-2025</span></p> </td> </tr> <tr> <td style="border: 1px solid #000000; padding: 4px;"> <p style="text-align: center;"><span style="color: #000000;">Cosmic</span></p> </td> <td style="border: 1px solid #000000; padding: 4px;"> <p style="text-align: center;"><span style="color: #000000;">&nbsp;</span><span style="color: #000000;">v102</span></p> </td> <td style="padding: 4px; border: 1px solid #000000;"> <p style="text-align: center;"><span style="color: #000000;">&nbsp;</span><span style="color: #000000;">v102</span></p> </td> </tr> <tr> <td style="border: 1px solid #000000; padding: 4px;"> <p style="text-align: center;"><span style="color: #000000;">DECIPHER</span></p> </td> <td style="border: 1px solid #000000; padding: 4px;"> <p style="text-align: center;"><span style="color: #000000;">07-Sep-2025</span></p> </td> <td style="padding: 4px; border: 1px solid #000000;"> <p style="text-align: center;"><span style="color: #000000;">07-Nov-2025</span></p> </td> </tr> <tr> <td style="padding: 4px; border: 1px solid #000000;"> <p style="text-align: center;"><span style="color: #000000;">UniProt Regions</span></p> </td> <td style="padding: 4px; border: 1px solid #000000;"> <p style="text-align: center;"><span style="color: #000000;">07-Jul-2025</span></p> </td> <td style="padding: 4px; border: 1px solid #000000;"> <p style="text-align: center;"><span style="color: #000000;">07-Nov-2025</span></p> </td> </tr> </tbody> </table> </div> </div> </div> </div> <p>&nbsp;</p> <p style="font-size: 16px;"><span style="color: #000000;"><span style="color: #000000;">Version 13.12.1 of VarSome, <a href="https://landing.varsome.com/varsome-api">VarSome API</a>, and <a href="https://landing.varsome.com/varsome-clinical">VarSome Clinical</a> was released on 13 November 2025.</span></span></p> <ul> <li> <p style="font-weight: normal;"><span style="color: #000000;">Fixed an issue that, in certain edge cases, prevented users from running gene list analyses and merging VCF analyses.</span></p> </li> <li> <p style="font-weight: normal;"><span style="color: #000000;">Added the ability to create filters for CNV analyses directly from the <em>Filter Sets</em> page.</span></p> </li> <li> <p style="font-weight: normal;"><span style="color: #000000;">Improved the enforcement of equivalency in the PS1/PM5 rules of the germline classification. These rules are now automatically disabled when necessary to prevent circular dependencies.</span></p> </li> <li> <p style="font-weight: normal;"><span style="color: #000000;">Resolved a minor inconsistency where the strength of PP3/BP4 predictions was not always limited to <em>Moderate</em> when either <em>PM1</em> or <em>PM5</em> had been triggered with <em>Moderate</em> strength, as described in our documentation.</span></p> </li> </ul> <p style="font-size: 16px;">&nbsp;</p> <p style="font-size: 16px;"><span style="color: #000000;"><span style="color: #000000;">Version 13.12.0 of VarSome was released on 23 October 2025.</span></span></p> <p style="font-size: 16px;">&nbsp;</p> <p style="font-size: 16px;"><span style="background-color: transparent; color: #000000;">This scheduled maintenance update focused on ensuring system stability and preparing the platform for upcoming improvements.</span></p> <p><em><span style="color: #000000;">note: ClinVar's most recent data release introduced major structural changes. To ensure data consistency and accurate integration, this update is under internal validation. ClinVar's monthly updates will resume after this validation process concludes.</span></em></p> <p>&nbsp;</p> <p style="font-size: 16px;"><span style="color: #000000;">Version 13.12.0 of <a href="https://landing.varsome.com/varsome-clinical">VarSome Clinical</a> will be released on 1 November 2025.</span></p> <h1 style="font-size: 20px;"><span style="color: #000000;">Summary of Key New Features</span></h1> <ul> <li><span style="color: #2ca591;"><a href="#cnv-filtering" style="color: #2ca591;">CNV filtering for Delly whole-genome analyses</a></span></li> <li><span style="color: #2ca591;"><a href="#tmb-msi" style="color: #2ca591;">TMB and MSI biomarker visualization</a></span></li> <li><span style="color: #2ca591;"><a href="#twist-assays" style="color: #2ca591;">Support for Twist UMI-based assays</a></span></li> <li><span style="color: #2ca591;"><a href="#par-masking" style="color: #2ca591;">PAR masking for hg38 reference genome</a></span></li> <li><span style="color: #2ca591;"><a href="#additions" style="color: #2ca591;">Editable group gene lists</a></span></li> <li><span style="color: #2ca591;"><a href="#additions" style="color: #2ca591;">Repeat expansion annotation from PacBio VCFs</a></span></li> <li><span style="color: #2ca591;"><a href="#additions" style="color: #2ca591;">Somatic PVS1 rule fix</a></span></li> <li><span style="color: #2ca591;"><a href="#additions" style="color: #2ca591;">ClinVar update temporarily on hold</a></span></li> </ul> <p style="font-size: 16px;"><span style="color: #000000;"><span style="color: #000000;">Version 13.12.2 of VarSome, <a href="https://landing.varsome.com/varsome-api">VarSome API</a>, and <a href="https://landing.varsome.com/varsome-clinical">VarSome Clinical</a> was released on 27 November 2025.</span></span></p> <h1 style="font-size: 20px;"><span style="color: #000000;">Summary of Key New Features</span></h1> <ul> <li style="font-size: 16px;"><span style="color: #000000;">25 updated databases</span> (<a href="https://varsome.com/datasources/">full list of databases</a>).</li> </ul> <h1><span style="font-size: 20px; color: #000000;">Updated Databases</span></h1> <div> <div> <div> <div> <span>&nbsp;</span> <span></span> <table style="border-collapse: collapse; table-layout: fixed; margin-left: auto; margin-right: auto; border: 1px solid #99acc2; width: 81.9972%; height: 1595.98px;"> <colgroup> <col style="width: 45.189%;"> <col style="width: 27.1478%;"> <col style="width: 27.4914%;"> </colgroup> <tbody> <tr style="height: 55.9844px;"> <th style="height: 55.9844px; border-style: solid; text-align: center; background-color: #9fc5e8; border-color: #000000;"> <p><strong>Database </strong></p> </th> <th style="height: 55.9844px; border-style: solid; text-align: center; background-color: #9fc5e8; border-color: #000000;"> <p><strong>Old version </strong></p> </th> <th style="height: 55.9844px; border-style: solid; text-align: center; background-color: #9fc5e8; border-color: #000000;"> <p><strong>New version </strong></p> </th> </tr> <tr style="height: 70px;"> <td style="border: 1px solid #000000; padding: 4px;"> <p style="text-align: center;"><span style="color: #000000;">CPIC</span></p> </td> <td style="border: 1px solid #000000; padding: 4px;"> <p style="text-align: center;"><span style="color: #000000;">07-Mar-2025</span></p> </td> <td style="padding: 4px; border: 1px solid #000000;"> <p style="text-align: center;"><span style="color: #000000;">07-Nov-2025</span></p> </td> </tr> <tr style="height: 70px;"> <td style="border: 1px solid #000000; padding: 4px;"> <p style="text-align: center;"><span style="color: #000000;">AACT</span></p> </td> <td style="border: 1px solid #000000; padding: 4px;"> <p style="text-align: center;"><span style="color: #000000;">07-Oct-2025</span></p> </td> <td style="padding: 4px; border: 1px solid #000000;"> <p style="text-align: center;"><span style="color: #000000;">07-Nov-2025</span></p> </td> </tr> <tr style="height: 70px;"> <td style="border: 1px solid #000000; padding: 4px;"> <p style="text-align: center;"><span style="color: #000000;">GWAS</span></p> </td> <td style="border: 1px solid #000000; padding: 4px;"> <p style="text-align: center;"><span style="color: #000000;">07-Sep-2025</span></p> </td> <td style="padding: 4px; border: 1px solid #000000;"> <p style="text-align: center;"><span style="color: #000000;">07-Nov-2025</span></p> </td> </tr> <tr style="height: 70px;"> <td style="border: 1px solid #000000; padding: 4px;"> <p style="text-align: center;"><span style="color: #000000;">gene2phenotype</span></p> </td> <td style="border: 1px solid #000000; padding: 4px;"> <p style="text-align: center;"><span style="color: #000000;">07-Sep-2025</span></p> </td> <td style="padding: 4px; border: 1px solid #000000;"> <p style="text-align: center;"><span style="color: #000000;">07-Nov-2025</span></p> </td> </tr> <tr style="height: 70px;"> <td style="border: 1px solid #000000; padding: 4px;"> <p style="text-align: center;"><span style="color: #000000;">Ensembl</span></p> </td> <td style="border: 1px solid #000000; padding: 4px;"> <p style="text-align: center;"><span style="color: #000000;">113</span></p> </td> <td style="padding: 4px; border: 1px solid #000000;"> <p style="text-align: center;"><span style="color: #000000;">115</span></p> </td> </tr> <tr style="height: 70px;"> <td style="border: 1px solid #000000; padding: 4px;"> <p style="text-align: center;"><span style="color: #000000;">HGNC</span></p> </td> <td style="border: 1px solid #000000; padding: 4px;"> <p style="text-align: center;"><span style="color: #000000;">13-Feb-2025</span></p> </td> <td style="padding: 4px; border: 1px solid #000000;"> <p style="text-align: center;"><span style="color: #000000;">07-Nov-2025</span></p> </td> </tr> <tr style="height: 70px;"> <td style="border: 1px solid #000000; padding: 4px;"> <p style="text-align: center;"><span style="color: #000000;">OMIM®</span></p> </td> <td style="border: 1px solid #000000; padding: 4px;"> <p style="text-align: center;"><span style="color: #000000;">16-Sep-2025</span></p> </td> <td style="padding: 4px; border: 1px solid #000000;"> <p style="text-align: center;"><span style="color: #000000;">16-Nov-2025</span></p> </td> </tr> <tr style="height: 70px;"> <td style="border: 1px solid #000000; padding: 4px;"> <p style="text-align: center;"><span style="color: #000000;">LOVD</span></p> </td> <td style="border: 1px solid #000000; padding: 4px;"> <p style="text-align: center;"><span style="color: #000000;">16-Sep-2025</span></p> </td> <td style="padding: 4px; border: 1px solid #000000;"> <p style="text-align: center;"><span style="color: #000000;">16-Nov-2025</span></p> </td> </tr> <tr style="height: 70px;"> <td style="border: 1px solid #000000; padding: 4px;"> <p style="text-align: center;"><span style="color: #000000;">OncoKB</span></p> </td> <td style="border: 1px solid #000000; padding: 4px;"> <p style="text-align: center;"><span style="color: #000000;">v5.1</span></p> </td> <td style="padding: 4px; border: 1px solid #000000;"> <p style="text-align: center;"><span style="color: #000000;">v5.3</span></p> </td> </tr> <tr style="height: 70px;"> <td style="border: 1px solid #000000; padding: 4px;"> <p style="text-align: center;"><span style="color: #000000;">Mondo</span></p> </td> <td style="border: 1px solid #000000; padding: 4px;"> <p style="text-align: center;"><span style="color: #000000;">07-Feb-2025</span></p> </td> <td style="padding: 4px; border: 1px solid #000000;"> <p style="text-align: center;"><span style="color: #000000;">&nbsp;</span><span style="color: #000000;">07-Nov-2025</span></p> </td> </tr> <tr style="height: 70px;"> <td style="border: 1px solid #000000; padding: 4px;"> <p style="text-align: center;"><span style="color: #000000;">ClinVar</span></p> </td> <td style="border: 1px solid #000000; padding: 4px;" rowspan="2"> <p style="text-align: center;"><span style="color: #000000;">&nbsp;</span><span style="color: #000000;">07-Jul-2025</span></p> </td> <td style="padding: 4px; border: 1px solid #000000;" rowspan="2"> <p style="text-align: center;"><span style="color: #000000;">&nbsp;</span><span style="color: #000000;">07-Nov-2025</span></p> </td> </tr> <tr style="height: 70px;"> <td style="border: 1px solid #000000; padding: 4px;"> <p style="text-align: center;"><span style="color: #000000;">ClinVar CNVs</span></p> </td> </tr> <tr style="height: 70px;"> <td style="border: 1px solid #000000; padding: 4px;"> <p style="text-align: center;"><span style="color: #000000;">RefSeq</span></p> </td> <td style="border: 1px solid #000000; padding: 4px;"> <p style="text-align: center;"><span style="color: #000000;">228</span></p> </td> <td style="padding: 4px; border: 1px solid #000000;"> <p style="text-align: center;"><span style="color: #000000;">232</span></p> </td> </tr> <tr style="height: 70px;"> <td style="border: 1px solid #000000; padding: 4px;"> <p style="text-align: center;"><span style="color: #000000;">dbSNP</span></p> </td> <td style="border: 1px solid #000000; padding: 4px;"> <p style="text-align: center;"><span style="color: #000000;">build 156</span></p> </td> <td style="padding: 4px; border: 1px solid #000000;"> <p style="text-align: center;"><span style="color: #000000;">build 157</span></p> </td> </tr> <tr style="height: 70px;"> <td style="border: 1px solid #000000; padding: 4px;"> <p style="text-align: center;"><span style="color: #000000;">dbVar</span></p> </td> <td style="border: 1px solid #000000; padding: 4px;"> <p style="text-align: center;"><span style="color: #000000;">07-Jun-2025</span></p> </td> <td style="padding: 4px; border: 1px solid #000000;"> <p style="text-align: center;"><span style="color: #000000;">07-Nov-2025</span></p> </td> </tr> <tr style="height: 70px;"> <td style="border: 1px solid #000000; padding: 4px;"> <p style="text-align: center;"><span style="color: #000000;">ClinGen</span></p> </td> <td style="border: 1px solid #000000; padding: 4px;" rowspan="4"> <p style="text-align: center;"><span style="color: #000000;">07-Sep-2025</span></p> </td> <td style="padding: 4px; border: 1px solid #000000;" rowspan="4"> <p style="text-align: center;"><span style="color: #000000;">07-Nov-2025</span></p> </td> </tr> <tr style="height: 70px;"> <td style="border: 1px solid #000000; padding: 4px;"> <p style="text-align: center;"><span style="color: #000000;">ClinGen CNVs</span></p> </td> </tr> <tr style="height: 70px;"> <td style="border: 1px solid #000000; padding: 4px;"> <p style="text-align: center;"><span style="color: #000000;">ClinGen Disease Validity</span></p> </td> </tr> <tr style="height: 70px;"> <td style="border: 1px solid #000000; padding: 4px;"> <p style="text-align: center;"><span style="color: #000000;">ClinGen Regions</span></p> </td> </tr> <tr style="height: 70px;"> <td style="border: 1px solid #000000; padding: 4px;"> <p style="text-align: center;"><span style="color: #000000;">ClinGen Variants</span></p> </td> <td style="border: 1px solid #000000; padding: 4px;"> <p style="text-align: center;"><span style="color: #000000;">07-Sep-2025</span></p> </td> <td style="padding: 4px; border: 1px solid #000000;"> <p style="text-align: center;"><span style="color: #000000;">07-Nov-2025</span></p> </td> </tr> <tr style="height: 70px;"> <td style="border: 1px solid #000000; padding: 4px;"> <p style="text-align: center;"><span style="color: #000000;">GHR</span></p> </td> <td style="border: 1px solid #000000; padding: 4px;"> <p style="text-align: center;"><span style="color: #000000;">07-Sep-2025</span></p> </td> <td style="padding: 4px; border: 1px solid #000000;"> <p style="text-align: center;"><span style="color: #000000;">07-Nov-2025</span></p> </td> </tr> <tr style="height: 70px;"> <td style="border: 1px solid #000000; padding: 4px;"> <p style="text-align: center;"><span style="color: #000000;">PharmGKB</span></p> </td> <td style="border: 1px solid #000000; padding: 4px;"> <p style="text-align: center;"><span style="color: #000000;">07-Sep-2025</span></p> </td> <td style="padding: 4px; border: 1px solid #000000;"> <p style="text-align: center;"><span style="color: #000000;">07-Nov-2025</span></p> </td> </tr> <tr> <td style="border: 1px solid #000000; padding: 4px;"> <p style="text-align: center;"><span style="color: #000000;">Cosmic</span></p> </td> <td style="border: 1px solid #000000; padding: 4px;"> <p style="text-align: center;"><span style="color: #000000;">&nbsp;</span><span style="color: #000000;">v102</span></p> </td> <td style="padding: 4px; border: 1px solid #000000;"> <p style="text-align: center;"><span style="color: #000000;">&nbsp;</span><span style="color: #000000;">v102</span></p> </td> </tr> <tr> <td style="border: 1px solid #000000; padding: 4px;"> <p style="text-align: center;"><span style="color: #000000;">DECIPHER</span></p> </td> <td style="border: 1px solid #000000; padding: 4px;"> <p style="text-align: center;"><span style="color: #000000;">07-Sep-2025</span></p> </td> <td style="padding: 4px; border: 1px solid #000000;"> <p style="text-align: center;"><span style="color: #000000;">07-Nov-2025</span></p> </td> </tr> <tr> <td style="padding: 4px; border: 1px solid #000000;"> <p style="text-align: center;"><span style="color: #000000;">UniProt Regions</span></p> </td> <td style="padding: 4px; border: 1px solid #000000;"> <p style="text-align: center;"><span style="color: #000000;">07-Jul-2025</span></p> </td> <td style="padding: 4px; border: 1px solid #000000;"> <p style="text-align: center;"><span style="color: #000000;">07-Nov-2025</span></p> </td> </tr> </tbody> </table> </div> </div> </div> </div> <p>&nbsp;</p> <p style="font-size: 16px;"><span style="color: #000000;"><span style="color: #000000;">Version 13.12.1 of VarSome, <a href="https://landing.varsome.com/varsome-api">VarSome API</a>, and <a href="https://landing.varsome.com/varsome-clinical">VarSome Clinical</a> was released on 13 November 2025.</span></span></p> <ul> <li> <p style="font-weight: normal;"><span style="color: #000000;">Fixed an issue that, in certain edge cases, prevented users from running gene list analyses and merging VCF analyses.</span></p> </li> <li> <p style="font-weight: normal;"><span style="color: #000000;">Added the ability to create filters for CNV analyses directly from the <em>Filter Sets</em> page.</span></p> </li> <li> <p style="font-weight: normal;"><span style="color: #000000;">Improved the enforcement of equivalency in the PS1/PM5 rules of the germline classification. These rules are now automatically disabled when necessary to prevent circular dependencies.</span></p> </li> <li> <p style="font-weight: normal;"><span style="color: #000000;">Resolved a minor inconsistency where the strength of PP3/BP4 predictions was not always limited to <em>Moderate</em> when either <em>PM1</em> or <em>PM5</em> had been triggered with <em>Moderate</em> strength, as described in our documentation.</span></p> </li> </ul> <p style="font-size: 16px;">&nbsp;</p> <p style="font-size: 16px;"><span style="color: #000000;"><span style="color: #000000;">Version 13.12.0 of VarSome was released on 23 October 2025.</span></span></p> <p style="font-size: 16px;">&nbsp;</p> <p style="font-size: 16px;"><span style="background-color: transparent; color: #000000;">This scheduled maintenance update focused on ensuring system stability and preparing the platform for upcoming improvements.</span></p> <p><em><span style="color: #000000;">note: ClinVar's most recent data release introduced major structural changes. To ensure data consistency and accurate integration, this update is under internal validation. ClinVar's monthly updates will resume after this validation process concludes.</span></em></p> <p>&nbsp;</p> <p style="font-size: 16px;"><span style="color: #000000;">Version 13.12.0 of <a href="https://landing.varsome.com/varsome-clinical">VarSome Clinical</a> will be released on 1 November 2025.</span></p> <h1 style="font-size: 20px;"><span style="color: #000000;">Summary of Key New Features</span></h1> <ul> <li><span style="color: #2ca591;"><a href="#cnv-filtering" style="color: #2ca591;">CNV filtering for Delly whole-genome analyses</a></span></li> <li><span style="color: #2ca591;"><a href="#tmb-msi" style="color: #2ca591;">TMB and MSI biomarker visualization</a></span></li> <li><span style="color: #2ca591;"><a href="#twist-assays" style="color: #2ca591;">Support for Twist UMI-based assays</a></span></li> <li><span style="color: #2ca591;"><a href="#par-masking" style="color: #2ca591;">PAR masking for hg38 reference genome</a></span></li> <li><span style="color: #2ca591;"><a href="#additions" style="color: #2ca591;">Editable group gene lists</a></span></li> <li><span style="color: #2ca591;"><a href="#additions" style="color: #2ca591;">Repeat expansion annotation from PacBio VCFs</a></span></li> <li><span style="color: #2ca591;"><a href="#additions" style="color: #2ca591;">Somatic PVS1 rule fix</a></span></li> <li><span style="color: #2ca591;"><a href="#additions" style="color: #2ca591;">ClinVar update temporarily on hold</a></span></li> </ul> <img src="https://track.hubspot.com/__ptq.gif?a=4384097&amp;k=14&amp;r=https%3A%2F%2Fupdates.varsome.com%2Fen%2Fvarsome-v.13.12.0&amp;bu=https%253A%252F%252Fupdates.varsome.com%252Fen&amp;bvt=rss" alt="" width="1" height="1" style="min-height:1px!important;width:1px!important;border-width:0!important;margin-top:0!important;margin-bottom:0!important;margin-right:0!important;margin-left:0!important;padding-top:0!important;padding-bottom:0!important;padding-right:0!important;padding-left:0!important; "> Platform Updates VarSome API VarSome Clinical VarSome.com Premium Release Thu, 23 Oct 2025 07:01:00 GMT xanthippi.papakonstanti@saphetor.com (Xanthippi Papakonstanti) https://updates.varsome.com/en/varsome-v.13.12.0 2025-10-23T07:01:00Z VarSome & VarSome Clinical v.13.11.0 https://updates.varsome.com/en/varsome-varsome-clinical-v.13.11.0 <p style="font-size: 16px;"><span style="color: #000000;"><span style="color: #000000;">Version 13.11.0 of VarSome and <a href="https://landing.varsome.com/varsome-clinical">VarSome Clinical</a> was released on 25 September 2025.</span></span></p> <h1 style="font-size: 20px;"><span style="color: #000000;">Summary of Key New Features</span></h1> <ul> <li style="font-size: 16px;"><span style="color: #000000;">17 updated databases</span> (<a href="https://varsome.com/datasources/">full list of databases</a>).</li> </ul> <p style="font-size: 16px;"><span style="color: #000000;"><span style="color: #000000;">Version 13.11.0 of VarSome and <a href="https://landing.varsome.com/varsome-clinical">VarSome Clinical</a> was released on 25 September 2025.</span></span></p> <h1 style="font-size: 20px;"><span style="color: #000000;">Summary of Key New Features</span></h1> <ul> <li style="font-size: 16px;"><span style="color: #000000;">17 updated databases</span> (<a href="https://varsome.com/datasources/">full list of databases</a>).</li> </ul> <img src="https://track.hubspot.com/__ptq.gif?a=4384097&amp;k=14&amp;r=https%3A%2F%2Fupdates.varsome.com%2Fen%2Fvarsome-varsome-clinical-v.13.11.0&amp;bu=https%253A%252F%252Fupdates.varsome.com%252Fen&amp;bvt=rss" alt="" width="1" height="1" style="min-height:1px!important;width:1px!important;border-width:0!important;margin-top:0!important;margin-bottom:0!important;margin-right:0!important;margin-left:0!important;padding-top:0!important;padding-bottom:0!important;padding-right:0!important;padding-left:0!important; "> Platform Updates VarSome API VarSome Clinical VarSome.com Premium Release Thu, 25 Sep 2025 05:54:59 GMT carl.smith@saphetor.com (Carl Smith) https://updates.varsome.com/en/varsome-varsome-clinical-v.13.11.0 2025-09-25T05:54:59Z VarSome & VarSome Clinical v.13.10.1 https://updates.varsome.com/en/varsome-varsome-clinical-v.13.10.0 <p><span style="color: #000000;">Version 13.10.1 of VarSome and <a href="https://landing.varsome.com/varsome-clinical">VarSome Clinical</a> was released on 18 September 2025.</span></p> <ul> <li> <p style="font-weight: normal;"><span style="color: #000000;">ACMG SF v3.3 has been added to the public gene list.</span></p> </li> <li> <p style="font-weight: normal;"><span style="color: #000000;">Users can now download all files belonging to a project from Illumina BaseSpace, not just individual samples. A minor correction has also been applied to the Illumina BaseSpace page to further improve download functionality.</span></p> </li> </ul> <p style="font-size: 16px;"><span style="color: #000000;"><span style="color: #000000;">Version 13.10.0 of VarSome and <a href="https://landing.varsome.com/varsome-clinical">VarSome Clinical</a> was released on 28 August 2025.</span></span></p> <h1 style="font-size: 20px;"><span style="color: #000000;">Summary of Key New Features</span></h1> <ul> <li style="font-size: 16px;"><span style="color: #000000;">16 updated databases</span> (<a href="https://varsome.com/datasources/">full list of databases</a>).</li> </ul> <p><span style="color: #000000;">Version 13.10.1 of VarSome and <a href="https://landing.varsome.com/varsome-clinical">VarSome Clinical</a> was released on 18 September 2025.</span></p> <ul> <li> <p style="font-weight: normal;"><span style="color: #000000;">ACMG SF v3.3 has been added to the public gene list.</span></p> </li> <li> <p style="font-weight: normal;"><span style="color: #000000;">Users can now download all files belonging to a project from Illumina BaseSpace, not just individual samples. A minor correction has also been applied to the Illumina BaseSpace page to further improve download functionality.</span></p> </li> </ul> <p style="font-size: 16px;"><span style="color: #000000;"><span style="color: #000000;">Version 13.10.0 of VarSome and <a href="https://landing.varsome.com/varsome-clinical">VarSome Clinical</a> was released on 28 August 2025.</span></span></p> <h1 style="font-size: 20px;"><span style="color: #000000;">Summary of Key New Features</span></h1> <ul> <li style="font-size: 16px;"><span style="color: #000000;">16 updated databases</span> (<a href="https://varsome.com/datasources/">full list of databases</a>).</li> </ul> <img src="https://track.hubspot.com/__ptq.gif?a=4384097&amp;k=14&amp;r=https%3A%2F%2Fupdates.varsome.com%2Fen%2Fvarsome-varsome-clinical-v.13.10.0&amp;bu=https%253A%252F%252Fupdates.varsome.com%252Fen&amp;bvt=rss" alt="" width="1" height="1" style="min-height:1px!important;width:1px!important;border-width:0!important;margin-top:0!important;margin-bottom:0!important;margin-right:0!important;margin-left:0!important;padding-top:0!important;padding-bottom:0!important;padding-right:0!important;padding-left:0!important; "> Platform Updates VarSome API VarSome Clinical VarSome.com Premium Release Thu, 18 Sep 2025 06:55:00 GMT carl.smith@saphetor.com (Carl Smith) https://updates.varsome.com/en/varsome-varsome-clinical-v.13.10.0 2025-09-18T06:55:00Z VarSome API Update - V. 13.8.0 https://updates.varsome.com/en/varsome-api-update-v.-13.8.0 <p style="font-size: 16px;"><span style="color: #000000;">On </span><strong><span style="color: #000000;">5 September 2025</span></strong><span style="color: #000000;"> we will be releasing the Q3 API changes for the VarSome API (</span><span style="font-size: 16px;"><a href="http://stable-api.varsome.com/">stable-api.varsome.com</a></span><span style="color: #000000;">).</span></p> <p style="font-size: 16px;"><span style="color: #000000;">On </span><strong><span style="color: #000000;">5 September 2025</span></strong><span style="color: #000000;"> we will be releasing the Q3 API changes for the VarSome API (</span><span style="font-size: 16px;"><a href="http://stable-api.varsome.com/">stable-api.varsome.com</a></span><span style="color: #000000;">).</span></p> <img src="https://track.hubspot.com/__ptq.gif?a=4384097&amp;k=14&amp;r=https%3A%2F%2Fupdates.varsome.com%2Fen%2Fvarsome-api-update-v.-13.8.0&amp;bu=https%253A%252F%252Fupdates.varsome.com%252Fen&amp;bvt=rss" alt="" width="1" height="1" style="min-height:1px!important;width:1px!important;border-width:0!important;margin-top:0!important;margin-bottom:0!important;margin-right:0!important;margin-left:0!important;padding-top:0!important;padding-bottom:0!important;padding-right:0!important;padding-left:0!important; "> VarSome API Release Mon, 25 Aug 2025 11:11:51 GMT carl.smith@saphetor.com (Carl Smith) https://updates.varsome.com/en/varsome-api-update-v.-13.8.0 2025-08-25T11:11:51Z