Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Edit custom filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1983 1
1984 1
1985 1
1986 2
1987 1
1988 1
1997 1
2000 1
2007 2
2010 1
2013 3
2014 1
2015 3
2016 2
2017 4
2018 2
2019 6
2020 7
2021 7
2022 8
2023 11
2024 11
2025 1
2026 2

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

75 results

Results by year

Filters applied: . Clear all
Page 1
New Designer Drugs.
Levine M, Lovecchio F. Levine M, et al. Emerg Med Clin North Am. 2021 Aug;39(3):677-687. doi: 10.1016/j.emc.2021.04.013. Epub 2021 Jun 9. Emerg Med Clin North Am. 2021. PMID: 34215409 Review.
In recent years, there has been an emergence of numerous novel drugs. Such toxicity may occur in both adolescents and adults. This article discusses the opioid epidemic and several emerging opioids, including buprenorphine, loperamide, fentanyl, fentanyl derivatives, and o …
In recent years, there has been an emergence of numerous novel drugs. Such toxicity may occur in both adolescents and adults. This ar …
Clinical Presentations and Treatment of Phenibut Toxicity and Withdrawal: A Systematic Literature Review.
Weleff J, Kovacevich A, Burson J, Nero N, Anand A. Weleff J, et al. J Addict Med. 2023 Jul-Aug 01;17(4):407-417. doi: 10.1097/ADM.0000000000001141. Epub 2023 Feb 3. J Addict Med. 2023. PMID: 37579098
METHODS: A comprehensive literature search was conducted using Medline (Ovid), Embase (Ovid), and Cochrane Library databases to capture all published cases on the presentations and management of phenibut toxicity or withdrawal. RESULTS: Sixty-two cases from 3 …
METHODS: A comprehensive literature search was conducted using Medline (Ovid), Embase (Ovid), and Cochrane Library databases to capture all …
Phenibut: A drug with one too many "buts".
Gurley BJ, Koturbash I. Gurley BJ, et al. Basic Clin Pharmacol Toxicol. 2024 Oct;135(4):409-416. doi: 10.1111/bcpt.14075. Epub 2024 Aug 28. Basic Clin Pharmacol Toxicol. 2024. PMID: 39197876 Free PMC article. Review.
Available literature points to adverse side effects associated with intoxication, withdrawal, and addiction to phenibut. Some of these effects can be life-threatening, requiring hospitalization and therapeutic interventions. ...As control over its online marketing s …
Available literature points to adverse side effects associated with intoxication, withdrawal, and addiction to phenibut. Some …
Phenibut: Review and Pharmacologic Approaches to Treating Withdrawal.
Penzak SR, Bulloch M. Penzak SR, et al. J Clin Pharmacol. 2024 Jun;64(6):652-671. doi: 10.1002/jcph.2414. Epub 2024 Feb 10. J Clin Pharmacol. 2024. PMID: 38339875 Review.
Increased public awareness of phenibut has led to a growing number of reports of acute intoxication and withdrawal. In this review, we describe the pharmacology of phenibut, the presentation and management of acute intoxication, and regulatory issues, placing …
Increased public awareness of phenibut has led to a growing number of reports of acute intoxication and withdrawal. In this re …
A Systematic Review of Phenibut Withdrawals.
Stewart C, Simonsen H, Satyasi SK, Ashraf N, Sukpraprut-Braaten S. Stewart C, et al. Cureus. 2024 Sep 6;16(9):e68775. doi: 10.7759/cureus.68775. eCollection 2024 Sep. Cureus. 2024. PMID: 39376891 Free PMC article. Review.
This is a systematic review of case reports of phenibut patients with withdrawal symptoms published in the PubMed database between January 2010 and October 2023. ...This review highlights the importance of collecting a thorough patient history, including supplements …
This is a systematic review of case reports of phenibut patients with withdrawal symptoms published in the PubMed database bet …
Phenibut Dependence and Withdrawal.
Sethi R, Ravishankar DA, Nagireddy R. Sethi R, et al. Prim Care Companion CNS Disord. 2021 Feb 18;23(1):19l02457. doi: 10.4088/PCC.19l02457. Prim Care Companion CNS Disord. 2021. PMID: 34000148 Free article. No abstract available.
Phenibut overdose.
Sankary S, Canino P, Jackson J. Sankary S, et al. Am J Emerg Med. 2017 Mar;35(3):516.e1-516.e2. doi: 10.1016/j.ajem.2016.08.067. Epub 2016 Sep 1. Am J Emerg Med. 2017. PMID: 27666756 No abstract available.
Toxidrome of an Easily Obtainable Nootropic: A Case Report of Phenibut Intoxication and Withdrawal Delirium.
Martin R, Buffenstein I, Cho D, Kiyokawa M. Martin R, et al. J Clin Psychopharmacol. 2023 Nov-Dec 01;43(6):507-510. doi: 10.1097/JCP.0000000000001759. Epub 2023 Sep 12. J Clin Psychopharmacol. 2023. PMID: 37930202 Review.
However, phenibut can lead to problems related to intoxication, dependency, and withdrawal, similar to other sedatives. METHODS/PROCEDURES: We present a case of phenibut intoxication and withdrawal delirium that provided diagnostic and management chall …
However, phenibut can lead to problems related to intoxication, dependency, and withdrawal, similar to other sedatives. METHOD …
Safety and Tolerability of the Anxiolytic and Nootropic Drug Phenibut: A Systematic Review of Clinical Trials and Case Reports.
Kupats E, Vrublevska J, Zvejniece B, Vavers E, Stelfa G, Zvejniece L, Dambrova M. Kupats E, et al. Pharmacopsychiatry. 2020 Sep;53(5):201-208. doi: 10.1055/a-1151-5017. Epub 2020 Apr 27. Pharmacopsychiatry. 2020. PMID: 32340063
There are discrepancies in the reported side effects of phenibut in clinical trials compared to those reported in cases of online-purchased phenibut dependence and intoxication. The current systematic review provides evidence that, at therapeutic doses, phenibut
There are discrepancies in the reported side effects of phenibut in clinical trials compared to those reported in cases of online-pur …
Quantity of phenibut in dietary supplements before and after FDA warnings.
Cohen PA, Ellison RR, Travis JC, Gaufberg SV, Gerona R. Cohen PA, et al. Clin Toxicol (Phila). 2022 Apr;60(4):486-488. doi: 10.1080/15563650.2021.1973020. Epub 2021 Sep 22. Clin Toxicol (Phila). 2022. PMID: 34550038
INTRODUCTION: Phenibut is used to treat anxiety, insomnia, alcohol withdrawal and other conditions in Russia. ...More than 80 cases of coma and death have been associated with phenibut consumption and withdrawal, and the FDA recently warned that the dr …
INTRODUCTION: Phenibut is used to treat anxiety, insomnia, alcohol withdrawal and other conditions in Russia. ...More than 80 …
75 results