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Hot Topics #33

BoltzGen, PPI prediction, Virtual Cell Challenge, and more.
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Hot Topics #32
Epitope-targeted de novo antibody design, Odyssey pLM, protein structure hallucination and more
Oct 23, 2025 • Jacob Pettit
Hot Topics #31 (July 22, 2024)
Peptide binder design, SE(3) motif scaffolding, AlphaFlow improvement, and more.
Jul 22, 2024 • Jacob Pettit
Hot Topics #30 (July 15, 2024)
Non-standard proteins and AlphaFold3, fusing approaches for protein structure prediction, predicting mutation effects, learning temporal distances, and…
Jul 15, 2024 • Jacob Pettit
Hot Topics #29 (Jul 8, 2024)
Discrete-Continuous diffusion models, diffusion-based priors, Dirichlet flow matching, and more.
Jul 8, 2024 • Jacob Pettit
Hot Topics #28 (July 1, 2024)
ESM3, SaprotHub, metric flow matching, investigating pLMs, and more.
Jul 2, 2024 • Jacob Pettit
Hot Topics #27 (June 17, 2024)
FoldFlow-2, BindGPT, compute-optimal pLMs, and deep learning for protein-ligand docking.
Jun 17, 2024 • Jacob Pettit
Hot Topics #26 (June 10, 2024)
Neural Flow Diffusion Models, benchmarking AlphaFold3, evolutionary-scale diffusion, and more.
Jun 10, 2024 • Jacob Pettit
The Merge
The Merge
Papers and code that are on my radar, sent out once a week. Focusing on machine learning (ML) and ML for Bio.
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