Histomorphological Study of Upper Gastrointestinal Endoscopic Biopsies
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Abstract
Background: Different benign and malignant lesions can arise from upper gastrointestinal tract. Histopathological study of endoscopic biopsies from upper gastrointestinal tract helps to permit early and exact diagnosis of the existing disease and also in further manangement of patients. Methods: This cross sectional type of descriptive study was conducted in the Department of Pathology, Rajshahi Medical College over a period of one year from January 2023 to December 2023. Tissue biopsy from the upper GIT was fixed with 10% formalin and was processed and stained with haematoxylin and eosin stain and was examined in Pathology Department of Rajshahi Medical College, Rajshahi. Out of the 44 cases, 22(50%) cases were histopathologically confirmed as neoplastic and the rest 22(50%) cases were as non-neoplastic. Results: A total of 44 cases were studied. Age ranging from 17 to 95 years was taken.Males were more prevalent. Stomach was the commonest site of endoscopic biopsies.The histopathology revealed non neoplastic lesions 22 (50%) and neoplastic lesions 22 (50%). Most common neoplastic lesions were gastric adenocarcinoma 21 (40.90%) and non-neoplastic lesions were nonspecific chronic gastritis 17 (38.63%). Conclusion: Endoscopic biopsy examination followed by histopathological assesment is a convanient procedure and current gold standard for the accurate diagnosis of patients with upper GIT lesions.
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