Prof. Dr. C. Höbartner - THE HÖBARTNER GROUP: ORGANIC AND BIOMOLECULAR CHEMISTRY

Prof. Dr. Claudia Höbartner

Universität Würzburg
Institut für Organische Chemie and
Center for Nanosystems Chemistry
Am Hubland
97074 Würzburg

Phone: +49 931 31-89693
Fax: +49 931 31-84755
claudia.hoebartner@uni-wuerzburg.de

Office Administration

Sabine Meyer

Phone: +49 931 31-85322
l-oc1.chemie@uni-wuerzburg.de

Welcome

Explore with us the exciting chemistry of nucleic acids! We synthesize chemically modified DNA and RNA, develop DNA catalysts, ribozymes and RNA aptamers, and explore their functions and innovative applications at the interface of chemistry and biology.

Just Published

BNB/NBN-Phenalenyl-2'-deoxyuridines as a Fluorophore–Quencher Pair in DNA Angew. Chem. Int. Ed. published April 27, 2026, e24671

2′-O-methylation-dependent installation of N²-methylguanosine in the U6 internal stem loop facilitates efficient spliceosome assembly Nature Communications, published April 24, 2026, 17:3793

Ribozymes for RNA-Catalyzed RNA Methylation and Labeling Angew. Chem. Int. Ed. published April 17, 2026, e22926

Alkyltransferase Ribozyme for Site-Specific N⁴-Cytidine Alkylation Angew. Chem. Int. Ed. 2026, 65, e6447137

For more papers, please visit our page "publications"

Further information about our research:

Video Gottfried Wilhelm Leibniz Prize 2023

Video Hansen Family Award 2023

News

SAMURI on the cover of Nat Chem Biol

The most recent Focus issue of Nature Chemical Biology features a collection of articles that showcase some of the recent progress in RNA chemical biology to reflect the synergy of mechanistic insights and technological innovations to drive RNA research forward.

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Dr Martin Volek is currently at the University of Würzburg on a Humboldt Fellowship

einBlick into the search amongst ten quadrillion DNA molecules

The university magazine einBlick profiles Martin and his research into DNA molecules as sensors for the discovery of new drugs.

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Breakthrough expands the catalytic and chemical capabilities of RNA

A ribozyme for site-specific N4-Cytidine alkylation was discovered by Evgeniia Dorinova in the Höbartner laboratory at the University of Würzburg.

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Hubland Süd, Geb. C1

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