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DMSO Resources: Notes from A Midwestern Doctor’s Articles (posted 10/15/24, updated 03/28/25 with short URLs to correct Substack bug link errors that occurred after original posting); updated 11/06/25 with Alzheimer’s dosing info.
We include AMD’s sources and information about:
Formulations
Gels vs Liquids
Dilution Calculators & Converters
AMD’s Recommended DMSO Sources
Safety
Topical Application (liquid application)
Dosing
Diluting (for liquid)
Skin Reactions
Advice for Specific Conditions
Disclaimer:
We are NOT recommending, prescribing, or providing medical information — because we are NOT qualified to do so. However, we thought you might appreciate some summarized information from A Midwestern Doctor’s recent series on DMSO (dimethyl sulfoxide).
→ We have used DMSO ourselves but are not endorsing (or non-endorsing) it.
→ We are not endorsing (or non-endorsing) the sources listed below.
→ We provide this information for your convenience only.
Source articles by A Midwestern Doctor:
DMSO Could Save Millions From Brain and Spinal Injury: tinyurl.com/5f3s9yjc
DMSO is a Miraculous Therapy for Chronic Pain and Musculoskeletal Injuries: tinyurl.com/3tvmj4kc
The Remarkable History and Safety of DMSO: tinyurl.com/yckhapmk
A Midwestern Doctor: 1960s “Sixty Minutes” Video on DMSO (10/14/24, video 15:57): tinyurl.com/2489scpa
Information Source for Notes Below:
DMSO is a Miraculous Therapy for Chronic Pain and Musculoskeletal Injuries. The decades of evidence DMSO revolutionizes the practice of medicine. By A Midwestern Doctor (09/29/24): tinyurl.com/3tvmj4kc
NOTES
Formulations:
Pure liquid (non-diluted, or 70% diluted depending on manufacturer; some offer additional dilutions)
Pure gel (70/30 Distilled Water Gel)
Mixed gel (typically mixed with aloe vera) — pure gels more common and higher rated in general
Gel Roll-On (scroll down the page linked just below) tinyurl.com/38v3y5j6
Gels vs. Liquids:
Gel can be easier to apply and possibly less messy. Liquid is less irritating and what AMD uses.
Aloe Vera: Homemade gels can be created by mixing liquid DMSO with pure (at least 99.5%) aloe vera gel.
Some 100% Pure Aloe Vera Gel Sources:
DSMO Store (Free Domestic Shipping USPS): tinyurl.com/yn3b8mzj
Vita Cost — Fruit of the Earth Aloe Vera 100% Gel: tinyurl.com/3vt7p773
Amazon — Fruit of the Earth Aloe Vera 100% Gel: tinyurl.com/yjvbwnye
Dilution Calculators & Converters (for the math challenged, like us ;-)
Dilution: tinyurl.com/3hn6s68k
Dilution: tinyurl.com/ywddm3y4
Converters: tinyurl.com/mtzhezuu
AMD’s Recommended DMSO Sources
We have provided manufacturer’s websites wherever practical.
The DMSO Store [newest, possibly purest, AMD uses and likes, high GMP standards, Free Domestic Shipping USPS]: tinyurl.com/347wyuyh
Suggest starting with DMSO Store manufacturer website; non-diluted liquid.
FAQs — Plastic vs Glass: tinyurl.com/34s33uka (plastic less expensive and best for travel or shorter term use; glass best for long-term storage and purity)
Non-Diluted Liquid - Non-diluted 99.995% Low Odor Pharma Grade Liquid Dimethyl Sulfoxide DMSO 8 oz.
8oz Glass Bottle: tinyurl.com/4ntd9byc
8oz BPA Free Plastic: tinyurl.com/5c8pzvc6
DMSO 70/30 Distilled Water Gel (BPA free plastic): tinyurl.com/mvsvwfvv
Jacob Lab [99.98% pure, most expensive, 70% solution, shipping ~$10]: tinyurl.com/4h7nb286
70% Liquid: tinyurl.com/cvxwbsub
70% Gel: tinyurl.com/yz5cumy5
Nature’s Gift [99.9% pure, 70% solution, AMD has used for a long time] tinyurl.com/2c934r2s (only gel is available on manufacturer's website)
70% Liquid: tinyurl.com/26b9byww (LIQUID CANNOT BE SHIPPED TO ALL LOCATIONS)
70% Gel Natures Gift: tinyurl.com/4zsxxeu2
Safety (patch tests, etc.) Information:
Topical Application (liquid application) Information: tinyurl.com/kb5bth97
Clean skin thoroughly first
Use cotton swab, spray bottle, natural fiber paintbrush, or (possibly best) fingers
Let dry about 20 minutes before putting on any clothing
Dosing Information:
70% often ideal, but can be diluted as needed if rashes occur.
Recommended: Dilute and increase concentration as needed.
Diluting Information (for liquid):
Although DMSO weighs a bit more than water, it's easier just to assume they are the same and use simple math to dilute. (See also “Dilution Calculators & Converters” above.)
Example: Start with 70% DMSO, and mix with two parts water and test. Then mix with one part water and test. If that is still tolerable, use 70% without diluting (what most people end up using).
Mixing DMSO with water will generate heat, which is normal.
Skin Reactions Information:
Irritated skin (e.g., redness, itching, or burning) normally temporary and passes (and often becomes less likely with subsequent doses of DMSO).
Higher concentrations of DMSO on the same spot can create scaling on the skin. Try different nearby areas.
Most skin issues occur with 90% rather than 70%.
DMSO will create NORMAL sensations in the skin (e.g., warmth, a bit of numbness, a pulsation or a prickling).
Advice for Specific Conditions (details at the link):
Acute bursitis
Acute back and neck strains
Acute Injuries
Arthritis
Blisters (60-75%)
Eczema (atopic dermatitis 40-65%)
Gout (75-80%)
Migraine Headaches (50%)
Restless leg syndrome (60-80%, brush or spray)
Scars (60-75% daily)
Spine Issues (70%)
Sunburns (30-60%, repeat after 3-5 hours)
Trigeminal Neuralgia
Alzheimer’s: tinyurl.com/3z74xcbd 🆕
