Sequence & Destroy by Evan Peikon | Substack

Issue #62 // Collider Bias In Genomics

Disentangling statistical artifacts from true biological effects

Jan 11 • Evan Peikon

Issue #61 // Orthogonal Validation Over Replication

The biology we study is constrained by the biology we can measure. The solution to this problem isn’t more reproducibility—It’s orthogonal validation…

Jan 4 • Evan Peikon

Issue #60 // Compression As Understanding

The Tension Between Mechanistic Understanding/Clinical Interpretability and Predictive Biology

Dec 28, 2025 • Evan Peikon

Issue #59 // Castles on Quicksand

A Consumer Health Tracking Story

Dec 15, 2025 • Evan Peikon

Issue #58 // How to Kill a Tumor

Three perspectives on rationale drug selection in personalized cancer therapy

Nov 30, 2025 • Evan Peikon

Most Popular

Issue #36 // Machine Learning: The Native Language of Biology

Apr 15, 2025 • Evan Peikon

Issue #46 // Computational Modeling of Branched Pathway Systems

Jul 7, 2025 • Evan Peikon

Connecting the Dots: A Guide to Multi-Omics Data

Oct 9, 2024 • Evan Peikon

The Bioinformatics Toolkit

Jan 19, 2025 • Evan Peikon

Sequence & Destroy by Evan Peikon

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