Controlling Growth
with
Automated Scalable Bioreactor for
Cell Therapy Manufacturing
Explore the Osilaris™ platform
At Scinus Cell Expansion we offer an Automated Cell Culture System to simplify ATMP manufacturing.
Osilaris™ is a unique benchtop bioreactor, designed for high-fold (>1000x) expansion of either adherent or suspension cells with proven protocols for MSC, T-cells, HEK, iPSC manufacturing.
Osilaris makes decentralized cell therapy manufacturing cost-efficient, less laborious, flexible and scalable with an automated, Class C cleanroom-ready design.
From vial to clinical dose in a single passage
Expand cells from start to finish without transfers, saving time and reducing contamination risks. Simplify your workflows and obtain billions of cells from a single cryovial.
Cost-Efficient GMP cell manufacturing
Take your process from research scale to clinical volumes in the same system, no need to switch platforms. Reduce
total cost of ownership and batch production costs with less equipment
overhead, consumables, reagents and labour commitment.
Take control of your culture
Achieve reproducible critical quality attributes (CQA) controlling in-line critical process parameters (CPP) like pH and Dissolved Oxygen (DO).
Designed around your cells
Flexible parameter control ensures your therapy drives the process, not the other way around.
Scinus Secures €3 Million Strategic Investment
The investment marks an important milestone in Scinus’ development and will support the accelerated commercial roll-out of the Osilaris™ Platform in key markets, while further strengthening the company’s governance and operational maturity.
T-cell manufacturing with Osilaris
Osilaris combines T-cell selection, activation, and expansion within a single closed system
"Scinus' bioreactor is the only system that offers a process compatible with patient-specific expansion of periosteum-derived cells for large bone defects"
We evaluated different and industry standard fixed-bed systems in the past, but the Scinus Cell Expansion platform has proven superior and now represents our gold standard technology. What sets the Scinus system apart is its remarkably low medium requirements, achieving unprecedented-fold expansion in a single, volume-expandable passage. The entire operation can be performed by one person, thanks to the system's intuitive handling and streamlined cell harvesting process.
"Scinus bioreactors have been a key investment toward our future manufacturing goals. "
The system addresses many next-generation requirements, including a closed setup compatible with tube welding, integrated sensors, low shear stress, bubble-free gas exchange, and an integrated seed train within a single expandable consumable. Early on, we also benefited from established hMSC protocols and Scinus’ process development support for new cell types. As early adopters, working with multiple system versions, we continue to grow with Scinus and value their ongoing support and expertise. The team’s knowledge and responsiveness have been instrumental, and we look forward to further integrating the platform into our automated processes.
