# Licence

As one of Open Targets flagship informatics products, the team that maintains the Open Targets Platform is committed to building open source tools and supporting open access research.

If you use our code and/or our data, please cite [our latest publication](https://platform-docs.opentargets.org/citation#latest-publication).

## **Data**

Open Targets Platform is marked with [CC0 1.0](http://creativecommons.org/publicdomain/zero/1.0?ref=chooser-v1). This dedicates the data to the public domain, allowing downstream users to consume the data without restriction.

The Platform also conforms to the EBI long-term data preservation [policies](https://www.ebi.ac.uk/long-term-data-preservation).

Please contact us on [the Open Targets Community](https://community.opentargets.org/) if you have questions about our licence or using our data and codebases.

## **Codebases**

The codebases that power the Platform - including our pipelines, GraphQL API, and React UI - are all open source and licensed under the [APACHE LICENSE, VERSION 2.0](https://www.apache.org/licenses/LICENSE-2.0).

You can find all of our code repositories on GitHub at <https://github.com/opentargets>.

## Data sources licensing

See list below if you are interested in knowing more about our data sources and their licensing status.

Please note that all data sources listed in the table, including the ones labeled with 'commercial use for Open Targets', have agreed for their data to be used without restriction by all Open Targets users.

| Data source                                                                                                     | Licence                                                                                                   |
| --------------------------------------------------------------------------------------------------------------- | --------------------------------------------------------------------------------------------------------- |
| [AlphaMissense](https://github.com/google-deepmind/alphamissense)                                               | CC-BY 4.0                                                                                                 |
| [Cancer Gene Census](https://cancer.sanger.ac.uk/census)                                                        | Commercial use for Open Targets                                                                           |
| [Cancer Genome Interpreter](https://www.cancergenomeinterpreter.org/biomarkers)                                 | CC-BY 4.0                                                                                                 |
| [Cell Ontology](https://obofoundry.org/ontology/cl.html)                                                        | CC BY 4.0                                                                                                 |
| [ChEMBL](https://www.ebi.ac.uk/chembl/)                                                                         | CC BY-SA 3.0                                                                                              |
| [ClinGen](https://clinicalgenome.org/)                                                                          | CC0 1.0                                                                                                   |
| [ClinVar](https://www.ncbi.nlm.nih.gov/clinvar/) (via [EVA](https://www.ebi.ac.uk/eva/))                        | [EMBL-EBI terms of use ](https://www.ebi.ac.uk/about/terms-of-use/)                                       |
| [EFO](https://www.ebi.ac.uk/efo/)                                                                               | Apache 2.0                                                                                                |
| [Ensembl](https://www.ensembl.org/index.html)                                                                   | CC-BY 4.0                                                                                                 |
| [Europe PMC](http://europepmc.org/)                                                                             | CC-BY, CC-BY-NC or CC0 license or open access (depending on publication licenses)                         |
| [eQTL Catalogue](https://www.ebi.ac.uk/eqtl/)                                                                   | CC-BY 4.0                                                                                                 |
| [Expression Atlas](https://www.ebi.ac.uk/gxa/home)                                                              | CC-BY 4.0                                                                                                 |
| [FAERS](https://www.fda.gov/drugs/surveillance/questions-and-answers-fdas-adverse-event-reporting-system-faers) | CC0 1.0                                                                                                   |
| [FinnGen R12](https://www.finngen.fi/en)                                                                        | Summary statistics can be requested [here](https://elomake.helsinki.fi/lomakkeet/124935/lomake.html).     |
| [Gene Ontology](http://geneontology.org/)                                                                       | CC-BY 4.0                                                                                                 |
| [Gene Signature](https://www.hsls.pitt.edu/obrc/index.php?page=URL1268854187)                                   | Apache 2.0                                                                                                |
| [Gene2Phenotype](https://www.ebi.ac.uk/gene2phenotype)                                                          | [EMBL-EBI terms of use](https://www.ebi.ac.uk/about/terms-of-use/)                                        |
| [Genomics England PanelApp](https://panelapp.genomicsengland.co.uk/)                                            | Commercial use for Open Targets                                                                           |
| [gnomAD](https://gnomad.broadinstitute.org/)                                                                    | CC0 1.0                                                                                                   |
| [GTEx](https://www.gtexportal.org)                                                                              | CC-BY 4.0                                                                                                 |
| [GWAS Catalog](https://www.ebi.ac.uk/gwas/home)                                                                 | [EMBL-EBI terms of use ](https://www.ebi.ac.uk/about/terms-of-use/)(Summary statistics are under CC0 1.0) |
| [HeCaTos](https://cordis.europa.eu/project/id/602156/results)                                                   | CC-BY 4.0                                                                                                 |
| [HPO](https://hpo.jax.org/app/)                                                                                 | CC0 1.0                                                                                                   |
| [Human Protein Atlas](http://www.proteinatlas.org/)                                                             | CC BY-SA 3.0                                                                                              |
| [Intact](https://www.ebi.ac.uk/intact/home)                                                                     | [EMBL-EBI terms of use](https://www.ebi.ac.uk/about/terms-of-use/)                                        |
| [IntOGen](http://www.intogen.org/search)                                                                        | CC0 1.0                                                                                                   |
| [MGI](http://www.informatics.jax.org/phenotypes.shtml)                                                          | CC-BY 4.0                                                                                                 |
| [MONDO](https://mondo.monarchinitiative.org)                                                                    | CC-BY 4.0                                                                                                 |
| [Orphanet](https://www.orpha.net/consor/cgi-bin/index.php)                                                      | CC-BY 4.0                                                                                                 |
| [panUKB](https://pan.ukbb.broadinstitute.org/)                                                                  | CC BY 4.0                                                                                                 |
| [PhenoDigm](https://www.sanger.ac.uk/tool/phenodigm/)                                                           | CC-BY 4.0                                                                                                 |
| [Probes and Drugs](https://www.probes-drugs.org/home/)                                                          | CC-BY 4.0                                                                                                 |
| [PROGENy](https://saezlab.github.io/progeny/)                                                                   | Apache 2.0                                                                                                |
| [Project Score](https://score.depmap.sanger.ac.uk/)                                                             | Commercial use for Open Targets                                                                           |
| [Reactome](https://reactome.org/)                                                                               | CC-BY 4.0                                                                                                 |
| [Sequence Ontology](http://www.sequenceontology.org/)                                                           | CC-BY 4.0                                                                                                 |
| [Signor](https://signor.uniroma2.it/) (via [Intact](https://www.ebi.ac.uk/intact/home))                         | [EMBL-EBI terms of use](https://www.ebi.ac.uk/about/terms-of-use/)                                        |
| [SLAPenrich](https://saezlab.github.io/SLAPenrich/)                                                             | MIT terms of use                                                                                          |
| [String DB](https://string-db.org/)                                                                             | CC-BY 4.0                                                                                                 |
| [TEP](https://www.thesgc.org/tep)                                                                               | CC-BY 4.0                                                                                                 |
| [Tox21](https://tox21.gov/overview/about-tox21/)                                                                | CC0 1.0                                                                                                   |
| [Uberon](https://obophenotype.github.io/uberon/)                                                                | CC BY 3.0                                                                                                 |
| [UKB-PPP](https://www.synapse.org/Synapse:syn51364943/wiki/622119)                                              | Apache 2.0                                                                                                |
| [UniProt](https://www.uniprot.org/)                                                                             | CC-BY 4.0                                                                                                 |
