BG_PKA

Protein kinase A

Landing page for protein kinase A (PKA).

PKA is a key regulator of normal cell function in various organs in the body. It is activated by cAMP action, and is inhibited by PKI.

Within cardiac cells, two holoenzymes exist: Type I and II.

Model

The below image shows the bond graph diagram of the reaction.

For a given holoenzyme: E - catalytic subunit of PKA. R - regulatory subunit of PKA.