CHANGiNG LiVES THROUGH LiViNG MEDiCiNE

CLiNiCAL-STAGE PRECiSiON ONCOLOGY AND PULMONARY DiSEASES

THE POWER
OF iNKT

About Us

MiNK Therapeutics is a cutting-edge clinical-stage company developing innovative allogeneic invariant natural killer T (iNKT) cell therapies for cancer and immune-mediated diseases. The lead product is an off-the-shelf therapy administered without lymphodepletion or HLA matching. These cells enhance both innate and adaptive immunity by combining the potent cytotoxicity of natural killer (NK) cells with the lasting memory response of T cells. MiNK has treated over 70 patients with solid tumors and severe acute respiratory distress syndrome with exceptional efficacy. Moreover, MiNK has shown the potential to engineer and edit these cells for precision targeting, further advancing their therapeutic potential.

Executive Leadership

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Scientific Advisory Board

Board of Directors

Management

Robert Stein, M.D., Ph.D.

Scientific Advisor

Robert Stein, M.D., Ph.D.
Scientific Advisor

Manuel Hidalgo, M.D., Ph.D.

Scientific Advisor

Manuel Hidalgo, M.D., Ph.D.
Scientific Advisor

Mark Exley, Ph.D.

Scientific Advisor

Mark Exley, Ph.D.
Scientific Advisor

Jenny Gumperz, Ph.D.

Scientific Advisor

Jenny Gumperz, Ph.D.
Scientific Advisor

Lydia Lynch, Ph.D.

Scientific Advisor

Lydia Lynch, Ph.D.
Scientific Advisor

Marcela Maus, M.D., Ph.D.

Scientific Advisor

Marcela Maus, M.D., Ph.D.
Scientific Advisor

Marc Van Dijk, Ph.D.

Scientific Advisor

Marc Van Dijk, Ph.D.
Scientific Advisor

Garo Armen, Ph.D.

Chairman

Garo Armen, Ph.D.
Chairman

Peter Behner

Director

Peter Behner
Director

Jennifer Buell, Ph.D.

President and CEO

Jennifer Buell, Ph.D.
President and CEO

Brian Corvese

Director

Brian Corvese
Director

Barbara Ryan

Director

Barbara Ryan
Director

Ulf Wiinberg

Director

Ulf Wiinberg
Director

Yekaterina Chudnovsky

Board Observer

Yekaterina Chudnovsky
Board Observer

Colonel (Ret.) John B. Holcomb, MD, FACS

Director

Colonel (Ret.) John B. Holcomb, MD, FACS
Director

Jennifer Buell, Ph.D.

President and CEO

Jennifer Buell, Ph.D.
President and CEO

Thiago Favano

Senior Director, Portfolio Operations

Thiago Favano
Senior Director, Portfolio Operations

Dr. Nils Rudqvist

Senior Director, Research

Dr. Nils Rudqvist
Senior Director, Research

Sandra Craig

Executive Director of Manufacturing

Sandra Craig
Executive Director of Manufacturing

Hayley Cullen

Director of Manufacturing

Hayley Cullen
Director of Manufacturing

Dr. Terese Hammond

Head of Inflammatory and Pulmonary Diseases

Dr. Terese Hammond
Head of Inflammatory and Pulmonary Diseases

Dr. Marco Purbhoo

Head of Translational Medicine

Dr. Marco Purbhoo
Head of Translational Medicine

Pipeline

MiNK's lead product candidate AGENT-797 is in multiple Phase 1 clinical trials with clinical and preclinical readouts anticipated later this year. Our research team is focused on developing potential first-or best-in-class therapies using a next- generation technology platform to develop novel engineered iNKT cell therapies and bispecific iNKT cell engagers.

Product

Target

Indication

Pre-clinical

IND-Enabling

Phase 1

Phase 2

Next milestone

agenT-797

Native iNKT

Severe Acute Lung Injury (ALI) (viral/bacterial induced ARDS)1
Phase 2
Graft versus Host Diseases (GvHD)
IND-Enabling

IND 2025

Disclosed under CDA
IND-Enabling

agenT-797 Combination Therapy

+ SoC ± BOT/BAL

Gastric Cancer
Phase 2

± PD-1

Solid Tumors
Phase 2

± Engagers

Solid Tumors
IND-Enabling

MiNK-215

FAP CAR IL-15

Solid Tumors
Phase 1

IND 2025

MiNK-413

BCMA CAR IL-15

MML/Auto-immune
IND-Enabling

IND Ready

MiNK-XXX

PRAME TCR

Solid Tumors
IND-Enabling

Additional Candidates

Disclosed under CDA

Solid Tumors
IND-Enabling

*Autologous T cell program IND-ready: allogeneic iNKT program in development