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    • Mashup Score: 0
      Uveitis findings determine referral urgency - 45 minute(s) ago

      Exam findings will show a comprehensive ophthalmologist when to refer a patient for uveitis, according to a speaker at Sunshine Eye & Retina.

      Source: www.healio.com
      Categories: General Medicine News, Ophthalmology
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      • Profile photo of 	Healio_OSN
        Healio_OSN

        From #SunshineEyeAndRetina: Clinicians should take a detailed ocular and systemic history and perform a dilated exam to determine if a referral for uveitis is necessary and how soon. Read more on @goHealio: 🔗 https://t.co/nycdyL6kpV @SunshineEyeCME

    • Mashup Score: 0
      VJSM - Insight Into Office Based Varicocelectomy - 46 minute(s) ago

      ISSM’s new Video Journal of Sexual Medicine (VJSM) is a peer-reviewed journal dedicated to publishing video content related to sexual medicine in general

      Source: www.vjsm.info
      Categories: General Medicine News, General Journals & Societ
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      • Profile photo of 	jsexmed
        jsexmed

        Office based varicocelectomy is a safe and efficient option for carefully selected patients. Avoiding general anesthesia reduces cost and recovery time while maintaining continuity of care. Learn more: https://t.co/1jNrlxgKF7 https://t.co/QnD9Zql669

    • Mashup Score: 0
      MPFL reconstruction with allograft may have clinically worse outcomes vs. autograft - 46 minute(s) ago

      NEW ORLEANS — Results showed patients who underwent a medial patellofemoral ligament reconstruction with either an allograft or autograft experienced similar complications, but the allograft group trended toward worse clinical outcomes.“Ultimately, this is something that we should continue to look at, and we should follow this cohort for an additional amount of time to see if this

      Source: www.healio.com
      Categories: General Medicine News
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      • Profile photo of 	OrthoToday
        OrthoToday

        🏃 Patients who underwent a #MPFL reconstruction with either an allograft or autograft experienced similar complications, but the allograft group trended toward worse clinical outcomes. #AAOS2026 @aaos1 https://t.co/krXxwpAY5k

    • Mashup Score: 0
      Senescent cancer-associated fibroblasts drive early-stage lymph node metastasis in pancreatic cancer through lactate-mediated metabolic-epigenetic rewiring - 46 minute(s) ago

      Abstract. Lymph node metastasis (LNM) in early-stage PDAC predicts systemic dissemination and poor survival, yet its underlying mechanisms remain elusive. Here, we demonstrated that senescent cancer-associated fibroblasts (senCAFs) drive lymphatic remodeling and LNM in early-stage PDAC. Mechanistically, senCAFs increased glucose metabolism and lactate production, which activated lactylation-mediated serine metabolism to protect lymphatic endothelial cells from oxidative stress. Moreover, we discovered CCR4+ Tregs from the draining lymph nodes accumulated around lymphatic vessels, which established an immunosuppressive peri-lymphatic niche. High throughput drug screening determined selective clearance of senCAFs via chidamide, attenuated tumor progression and improved chemo-immunotherapeutic efficacy. We subsequently initiated a clinical trial (chidamide and nab-paclitaxel/gemcitabine plus anti-PD-1/CTLA-4) in metastatic PDAC patients and reported its preliminary promising results. Coll

      Source: aacrjournals.org
      Categories: General Medicine News
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      • Profile photo of 	CD_AACR
        CD_AACR

        Now online: Senescent cancer-associated fibroblasts drive early-stage lymph node metastasis in pancreatic cancer through lactate-mediated metabolic-epigenetic rewiring https://t.co/7KS1WIS9Yv https://t.co/Yz5paFQIVL

    • Mashup Score: 0
      Oral Semaglutide and Change in Cardiovascular Risk Factors in High-Risk Type 2 Diabetes - 46 minute(s) ago

      This post hoc secondary analysis of the SOUL randomized clinical trial investigates whether treatment with oral semaglutide was associated with changes in atherosclerotic cardiovascular disease risk factors vs placebo among participants with type 2 diabetes.

      Source: jamanetwork.com
      Categories: General Medicine News
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      • Profile photo of 	JAMACardio
        JAMACardio

        #Type2Diabetes patients at high cardiovascular risk receiving oral #semaglutide demonstrated early and sustained improvements in glycated hemoglobin, body weight, systolic blood pressure, and lipid profiles vs placebo. https://t.co/EoHcvlamyl https://t.co/z3UdpiUlni

    • Mashup Score: 0
      Safety Evaluation of 4 Red Light Therapy Devices for Myopia - 46 minute(s) ago

      This quality improvement study assesses the optical output and safety classification of 4 commercially available red light therapy devices for myopia management using American National Standards Institute guidelines.

      Source: jamanetwork.com
      Categories: General Medicine News, Ophthalmology
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      • Profile photo of 	JAMAOphth
        JAMAOphth

        In this quality improvement study, laser-based red light therapy devices for myopia reached #ANSI safety exposure limits in seconds, raising safety concerns for recommended treatment times in pediatric patients. https://t.co/SnqIjG34cb https://t.co/hwgVMdMsdk

    • Mashup Score: 0
      Ocular Toxic Effects During Mirvetuximab Soravtansine Therapy - 46 minute(s) ago

      This case series describes the management and outcomes of ocular toxic effects associated with mirvetuximab soravtansine therapy in female patients with folate receptor α–positive gynecologic malignant neoplasms.

      Source: jamanetwork.com
      Categories: General Medicine News
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      • Profile photo of 	JAMAOnc
        JAMAOnc

        Ocular toxic effects including keratopathy, blurred vision, cataract progression, and uveitis were common but generally reversible during mirvetuximab soravtansine therapy for FRα-positive gynecologic cancers. https://t.co/omVYeWbhHJ https://t.co/g7DcJYdeqD

    • Mashup Score: 0
      Pertussis Infection in Adults - 46 minute(s) ago

      This JAMA Insights discusses the epidemiology, transmission, and risk factors for pertussis, also referred to as whooping cough, in adults.

      Source: jamanetwork.com
      Categories: General Medicine News
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      • Profile photo of 	JAMA_current
        JAMA_current

        Pertussis, or #WhoopingCough, is a common cause of severe and prolonged cough in adults in the US. 💡 Learn more about the epidemiology, transmission, and risk factors for pertussis in this JAMA Insights: https://t.co/6a5gP0ZcAK https://t.co/rxgupnM74C

    • Mashup Score: 0
      Labos: The cold hard truth about cold medications - 46 minute(s) ago

      archived 28 Mar 2026 11:53:30 UTC

      Source: archive.ph
      Categories: General Medicine News
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      • Profile photo of 	pash22
        pash22

        The cold hard truth about cold medications: Over-the-counter products for sale at pharmacies may alleviate symptoms and make you feel less crummy, but they are not cures. https://t.co/56er5a38X7 via @drlabos https://t.co/kzfjND6Ph8

    • Mashup Score: 0
      Jesse Roth, Who Advanced the Understanding of Diabetes, Dies at 91 (Gift Article) - 48 minute(s) ago

      His research showed that Type 2 diabetes was caused by insulin resistance at the cellular level, a controversial idea that initially met with disbelief.

      Source: www.nytimes.com
      Categories: General Medicine News
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      • Profile photo of 	jflier
        jflier

        Explore this gift article from The New York Times. You can read it for free without a subscription. https://t.co/VIORNnKy34

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