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Mashup Score: 0Uveitis findings determine referral urgency - 45 minute(s) ago
Exam findings will show a comprehensive ophthalmologist when to refer a patient for uveitis, according to a speaker at Sunshine Eye & Retina.
Source: www.healio.comCategories: General Medicine News, OphthalmologyTweet
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Mashup Score: 0VJSM - Insight Into Office Based Varicocelectomy - 46 minute(s) ago
ISSM’s new Video Journal of Sexual Medicine (VJSM) is a peer-reviewed journal dedicated to publishing video content related to sexual medicine in general
Source: www.vjsm.infoCategories: General Medicine News, General Journals & SocietTweet
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Mashup Score: 0MPFL reconstruction with allograft may have clinically worse outcomes vs. autograft - 46 minute(s) ago
NEW ORLEANS — Results showed patients who underwent a medial patellofemoral ligament reconstruction with either an allograft or autograft experienced similar complications, but the allograft group trended toward worse clinical outcomes.“Ultimately, this is something that we should continue to look at, and we should follow this cohort for an additional amount of time to see if this
Source: www.healio.comCategories: General Medicine NewsTweet
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Mashup Score: 0Senescent cancer-associated fibroblasts drive early-stage lymph node metastasis in pancreatic cancer through lactate-mediated metabolic-epigenetic rewiring - 46 minute(s) ago
Abstract. Lymph node metastasis (LNM) in early-stage PDAC predicts systemic dissemination and poor survival, yet its underlying mechanisms remain elusive. Here, we demonstrated that senescent cancer-associated fibroblasts (senCAFs) drive lymphatic remodeling and LNM in early-stage PDAC. Mechanistically, senCAFs increased glucose metabolism and lactate production, which activated lactylation-mediated serine metabolism to protect lymphatic endothelial cells from oxidative stress. Moreover, we discovered CCR4+ Tregs from the draining lymph nodes accumulated around lymphatic vessels, which established an immunosuppressive peri-lymphatic niche. High throughput drug screening determined selective clearance of senCAFs via chidamide, attenuated tumor progression and improved chemo-immunotherapeutic efficacy. We subsequently initiated a clinical trial (chidamide and nab-paclitaxel/gemcitabine plus anti-PD-1/CTLA-4) in metastatic PDAC patients and reported its preliminary promising results. Coll
Source: aacrjournals.orgCategories: General Medicine NewsTweet
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Mashup Score: 0Oral Semaglutide and Change in Cardiovascular Risk Factors in High-Risk Type 2 Diabetes - 46 minute(s) ago
This post hoc secondary analysis of the SOUL randomized clinical trial investigates whether treatment with oral semaglutide was associated with changes in atherosclerotic cardiovascular disease risk factors vs placebo among participants with type 2 diabetes.
Source: jamanetwork.comCategories: General Medicine NewsTweet
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Mashup Score: 0Safety Evaluation of 4 Red Light Therapy Devices for Myopia - 46 minute(s) ago
This quality improvement study assesses the optical output and safety classification of 4 commercially available red light therapy devices for myopia management using American National Standards Institute guidelines.
Source: jamanetwork.comCategories: General Medicine News, OphthalmologyTweet
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Mashup Score: 0Ocular Toxic Effects During Mirvetuximab Soravtansine Therapy - 46 minute(s) ago
This case series describes the management and outcomes of ocular toxic effects associated with mirvetuximab soravtansine therapy in female patients with folate receptor α–positive gynecologic malignant neoplasms.
Source: jamanetwork.comCategories: General Medicine NewsTweet
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Mashup Score: 0Pertussis Infection in Adults - 46 minute(s) ago
This JAMA Insights discusses the epidemiology, transmission, and risk factors for pertussis, also referred to as whooping cough, in adults.
Source: jamanetwork.comCategories: General Medicine NewsTweet
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Mashup Score: 0Labos: The cold hard truth about cold medications - 46 minute(s) ago
archived 28 Mar 2026 11:53:30 UTC
Source: archive.phCategories: General Medicine NewsTweet
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Mashup Score: 0Jesse Roth, Who Advanced the Understanding of Diabetes, Dies at 91 (Gift Article) - 48 minute(s) ago
His research showed that Type 2 diabetes was caused by insulin resistance at the cellular level, a controversial idea that initially met with disbelief.
Source: www.nytimes.comCategories: General Medicine NewsTweet
From #SunshineEyeAndRetina: Clinicians should take a detailed ocular and systemic history and perform a dilated exam to determine if a referral for uveitis is necessary and how soon. Read more on @goHealio: 🔗 https://t.co/nycdyL6kpV @SunshineEyeCME