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  • Nature (6)
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Spatial nature comm scaled
Spatial fibroblast niches define Crohn’s fistulae
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Jcl insight
Matrix metalloproteinases are hallmark early biomarkers and therapeutic targets in FSHD
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Cell report thumbnail
A single-cell and spatial wheat root atlas with cross species annotations delineates conserved tissue specific marker genes and regulators
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Borderzone cardiomyocytes and macrophages regulate extracellular matrix remodeling to promote cardiomyocyte protrusion during cardiac
Border-zone cardiomyocytes and macrophages regulate extracellular matrix remodeling to promote cardiomyocyte protrusion during cardiac regeneration
Florian Constanty and colleagues investigate the involvement of border-zone cardiomyocytes and macrophages in the remodeling of the extracellular matrix (ECM) to facilitate cardiomyocyte invasion during cardiac regeneration in zebrafish. The study reveals that these border-zone cardiomyocytes and macrophages actively contribute to modifying the ECM environment, which promotes the invasion of…
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New project 3
Dual and spatially resolved drought responses in the Arabidopsis leafmesophyll revealed by single-cell transcriptomics
Drought stress imposes severe challenges on agriculture by impacting crop performance. Understanding drought responses in plants at a cellular level is a crucial first step towards engineering improved drought resilience. However, the molecular responses to drought are complex as they depend on multiple factors including the severity of drought, the…
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Antigen presentation plays positive roles in the regenerative response to cardiac injury in zebrafish
Antigen presentation plays positive roles in the regenerative response to cardiac injury in zebrafish
Cardiera-da-Silva et al. investigate the role of antigen presentation in the process of heart regeneration in zebrafish, as this species possesses a remarkable ability to regenerate cardiac tissue after injury. The research found that antigen presentation, a process typically associated with the immune system’s response to pathogens, also supports heart…
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