{"id":18096,"date":"2022-02-01T00:00:00","date_gmt":"2022-02-01T00:00:00","guid":{"rendered":"https:\/\/hdbuzzwp.codev.codev\/?p=18096"},"modified":"2022-05-12T00:00:00","modified_gmt":"2022-05-12T00:00:00","slug":"317-2","status":"publish","type":"post","link":"https:\/\/ko.hdbuzz.net\/317-2\/","title":{"rendered":"\uacbd\uad6c \uc57d\ubb3c\uc740 \ud5cc\ud305\ud2f4 \uc218\uce58\ub97c \ub0ae\ucd94\ub294 \uc774\uc57c\uae30\ub97c \ubc14\uafc0 \uc218 \uc788\uc2b5\ub2c8\ub2e4."},"content":{"rendered":"\n

\ud5cc\ud305\ud2f4 \uc218\uce58\ub97c \ub0ae\ucd94\ub294 \uac83\uc740 HD \uc5f0\uad6c\uc5d0\uc11c \ub9ce\uc740 \uad00\uc2ec\uc744 \uc5bb\uc5c8\uc73c\uba70 \uadf8\ub9cc\ud55c \uc774\uc720\uac00 \uc788\uc2b5\ub2c8\ub2e4. HD\uc758 \uc6d0\uc778\uc778 \ud5cc\ud305\ud2f4 \ub2e8\ubc31\uc9c8\uc744 \uc9c1\uc811 \ud45c\uc801\uc73c\ub85c \uc0bc\ub3c4\ub85d \uc124\uacc4\ub41c \ucd5c\ucd08\uc758 \uc7a0\uc7ac\uc801 \uce58\ub8cc\ubc95\uc774\uc5c8\uc2b5\ub2c8\ub2e4. \uadf8\ub7ec\ub098 \ud604\uc7ac\uc758 \ud5cc\ud305\ud2f4 \uc800\ud558 \uc811\uadfc\ubc95\uc5d0\ub294 \uc81c\ud55c\uc774 \uc788\uc2b5\ub2c8\ub2e4. \uc804\ub2ec\uc744 \uc704\ud574 \ucc99\uc218\uc561\uc73c\ub85c\uc758 \uc804\ub2ec \ub610\ub294 \ub1cc \uc218\uc220\uc774 \ud544\uc694\ud558\uace0, \ub1cc \ub0b4\uc5d0\uc11c \uc81c\ud55c\ub41c \ubd84\ud3ec\ub97c \ub098\ud0c0\ub0bc \uc218 \uc788\uace0, \ud608\uc561-\ub1cc \uc7a5\ubcbd\uc744 \ud1b5\uacfc\ud558\uc9c0 \uc54a\uc2b5\ub2c8\ub2e4(\uc694\ucd94 \ucc9c\uc790\uac00 \ud544\uc694\ud55c \uc774\uc720\uc785\ub2c8\ub2e4. \ub610\ub294 \ub1cc \uc218\uc220). \uadf8\ub4e4\uc740 \ub610\ud55c “\ub9d0\ucd08” \uc870\uc9c1\uc5d0\uc11c \ub1cc \uc678\ubd80\uc758 \ud5cc\ud305\ud2f4\uc744 \uac10\uc18c\uc2dc\ud0a4\uc9c0 \uc54a\uc2b5\ub2c8\ub2e4.<\/p>\n\n\n\n\n

PTC Therapeutics\uc758 \uacfc\ud559\uc790\ub4e4\uc740 \ucd5c\uadfc\uc5d0 \uc720\uba85\ud55c \uc800\ub110\uc778 Nature Communications\uc5d0 \uacbd\uad6c\ub85c \ubcf5\uc6a9\ud560 \uc218 \uc788\uace0 \ub1cc\uc640 \uc2e0\uccb4 \uc804\uccb4\uc5d0 \ubd84\ud3ec\ud558\ub294 \ud5cc\ud305\ud2f4\uc744 \ub0ae\ucd94\ub294 \uc77c\ub828\uc758 \uc57d\ubb3c \ubd84\uc790\ub97c \uc124\uba85\ud558\ub294 \uc5f0\uad6c \uacb0\uacfc\ub97c \ubc1c\ud45c\ud588\uc2b5\ub2c8\ub2e4. 5\ub144 \uc804\ub9cc \ud574\ub3c4 \uacf5\uc0c1\uacfc\ud559 \uc18c\uc124\ucc98\ub7fc \ub4e4\ub838\uc744 \uacb0\uacfc\ub2e4. \uadf8\ub7ec\ub098 2020\ub144 \uc774\ud6c4\uc758 \uc138\uc0c1\uc5d0\uc11c \uacbd\uc774\ub85c\uc6c0\uc740 \uba48\ucd94\uc9c0 \uc54a\uc2b5\ub2c8\ub2e4! \ub530\ub77c\uc11c \uadf8\ub4e4\uc758 \ub370\uc774\ud130\uac00 \ubcf4\uc5ec\uc8fc\ub294 \uac83\uacfc \ud5cc\ud305\ud2f4 \uc218\uce58\ub97c \ub0ae\ucd94\ub294 \uac83\uc774 \ubb34\uc5c7\uc744 \uc758\ubbf8\ud558\ub294\uc9c0 \uc790\uc138\ud788 \uc0b4\ud3b4\ubcf4\uaca0\uc2b5\ub2c8\ub2e4.<\/p>\n\n\n\n\n

\uac74\ucd08\ub354\ubbf8 \uc18d\uc758 \ubc14\ub298<\/h2>\n\n\n\n\n

PTC\ub294 \uc57d 300,000\uac1c\uc758 \uc11c\ub85c \ub2e4\ub978 \ubd84\uc790 \ub77c\uc774\ube0c\ub7ec\ub9ac\ub97c \uc2a4\ud06c\ub9ac\ub2dd\ud558\ub294 \uac83\uc73c\ub85c \uc2dc\uc791\ud588\uc2b5\ub2c8\ub2e4! \uadf8\ub4e4\uc740 HD \ud658\uc790\uc5d0\uc11c \uc720\ub798\ud55c \uc138\ud3ec\uc5d0\uc11c \uc774\ub4e4 \ubd84\uc790 \uac01\uac01\uc744 \ud14c\uc2a4\ud2b8\ud588\uc2b5\ub2c8\ub2e4. \uc774\uac83\uc740 \ubd84\uc790\uac00 \uc778\uac04\uc758 \uc138\ud3ec\uc5d0 \ubbf8\uce60 \uc601\ud5a5\uc744 \uc120\ubcc4\ud558\uae30 \ub54c\ubb38\uc5d0 \uad00\uc2ec \ubd84\uc790\ub97c \u200b\u200b\uc2dd\ubcc4\ud558\uae30 \uc704\ud55c \uc720\ub9dd\ud55c \uccab \ubc88\uc9f8 \ud1b5\uacfc\uc785\ub2c8\ub2e4. \uc885\uc885 \uc57d\ubb3c\uc740 \uacfc\ud559\uc790\ub4e4\uc774 \uc0ac\ub78c\uc744 \ub300\uc0c1\uc73c\ub85c \ud14c\uc2a4\ud2b8\ud558\uae30 \uc804\uc5d0 \ub3d9\ubb3c \ubaa8\ub378\uc5d0\uc11c\ub9cc \uc5f0\uad6c\ub97c \uc218\ud589\ud55c\ub2e4\uba74 \uacfc\ud559\uc790\ub4e4\uc774 \uc0dd\uac01\ud588\ub358 \ubc29\uc2dd\uc73c\ub85c \uc791\ub3d9\ud558\uc9c0 \uc54a\uc2b5\ub2c8\ub2e4. \uba3c\uc800 \uc778\uac04 \uc138\ud3ec\ub97c \uc0b4\ud3b4\ubcf4\uba74 \uc57d\ubb3c \ubd84\uc790\uac00 \uc6b0\ub9ac\uac00 \uac00\uc7a5 \uad00\uc2ec\uc744 \uac16\uace0 \uc788\ub294 \uc720\uc77c\ud55c \uc720\uae30\uccb4\uc778 \uc0ac\ub78c\uc5d0\uac8c \uc758\ub3c4\ud55c \uc601\ud5a5\uc744 \ubbf8\uce60 \uac83\uc784\uc744 \uc2dc\uc0ac\ud569\ub2c8\ub2e4.<\/p>\n\n\n\n\n\n

\"HTT-C2\ub97c
HTT-C2\ub97c \ucc3e\ub294 \uac83\uc740 \uac74\ucd08 \ub354\ubbf8\uc5d0\uc11c \ubc14\ub298\uc744 \ucc3e\ub294 \uac83\uacfc \uac19\uc558\uc2b5\ub2c8\ub2e4. HTT-C2\ub294 \ud5cc\ud305\ud2f4 \uc218\uce58\ub97c \ub0ae\ucd9c \uc218 \uc788\uc744 \ubfd0\ub9cc \uc544\ub2c8\ub77c \uc54c\uc57d\uc73c\ub85c \ubcf5\uc6a9\ud560 \uc218\ub3c4 \uc788\uace0 \ud608\uc561\ub1cc\uc7a5\ubcbd\uc744 \ud1b5\uacfc\ud558\uae30\ub3c4 \ud569\ub2c8\ub2e4.\n\n<\/figcaption><\/figure>\n\n\n\n\n

\uba54\uc2dc\uc9c0\ub97c\ubc14\uafb8\ub2e4<\/h2>\n\n\n\n\n

PTC\uc758 \uacfc\ud559\uc790\ub4e4\uc740 300,000\uac1c\uc758 \ubd84\uc790 \uc911\uc5d0\uc11c \uc778\uac04 \uc138\ud3ec\uc5d0\uc11c \ud5cc\ud305\ud2f4\uc744 \ub0ae\ucd9c \uc218 \uc788\ub294 \ub450 \uac00\uc9c0 \uc720\ub9dd\ud55c \ubd84\uc790\ub85c \uc881\ud600\uc84c\uc2b5\ub2c8\ub2e4. \ub450 \ubd84\uc790 \ubaa8\ub450 “\uc811\ud569 \uc870\uc808\uc81c"\uc774\uba70, \uc774\ub294 \ud5cc\ud305\ud2f4 \ub2e8\ubc31\uc9c8\uc744 \uc0dd\uc131\ud558\ub294 \uba54\uc2dc\uc9c0\ub97c \uc77d\ub294 \ubc29\uc2dd\uc744 \ubcc0\uacbd\ud558\uc5ec \ud5cc\ud305\ud2f4 \uc218\uce58\ub97c \ub0ae\ucd9c \uc218 \uc788\uc74c\uc744 \uc758\ubbf8\ud569\ub2c8\ub2e4. PTC\uc758 \uacfc\ud559\uc790\ub4e4\uc740 \uacc4\uc18d\ud574\uc11c \ub2e4\ub978 \uc2e4\ud5d8\uc5d0\uc11c \uc774\ub7ec\ud55c \ubd84\uc790\ub97c \ubd84\uc11d\ud588\uc73c\uba70 HTT-C2\ub77c\uace0 \ud558\ub294 \ub9e4\uc6b0 \uc720\uc0ac\ud55c \ubd84\uc790\ub3c4 \uad00\ucc30\ud588\uc2b5\ub2c8\ub2e4.<\/p>\n\n\n\n\n

\uac01 \uc720\uc804\uc790\ub97c \ub3d9\ud654\ucc45\ucc98\ub7fc \uc0dd\uac01\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \uc720\uc804\uc790 \ub610\ub294 \uc2a4\ud1a0\ub9ac\uc758 \uc2dc\ud000\uc2a4\uac00 \u200b\u200b\ub05d\ub098\uba74 \ub9c8\uc9c0\ub9c9 \ubd80\ubd84\uc740 "The End"\ub97c \uc77d\uace0 \ud574\ub2f9 \uc720\uc804\uc790\uc758 \uc2dc\ud000\uc2a4\uac00 \u200b\u200b\uc644\ub8cc\ub418\uc5c8\uc74c\uc744 \uc138\ud3ec\uc5d0 \uc54c\ub9bd\ub2c8\ub2e4. \uc774 \uc811\ud569 \ubcc0\uc870\uae30\ub294 \ub9c8\uc9c0\ub9c9 \ud398\uc774\uc9c0\ub97c \uc704\ub85c \uc774\ub3d9\ud558\uc5ec \uc791\ub3d9\ud558\ubbc0\ub85c \uc2a4\ud1a0\ub9ac\ub294 \uc2dc\ud000\uc2a4\uac00 \u200b\u200b\ub05d\ub098\uae30 \uc804\uc5d0 "The End"\ub85c \uc77d\uc2b5\ub2c8\ub2e4. \uc774\uc57c\uae30\uac00 \ub354 \uc774\uc0c1 \uc758\ubbf8\uac00 \uc5c6\uae30 \ub54c\ubb38\uc5d0 \uc138\ud3ec\ub294 \uadf8 \uba54\uc2dc\uc9c0\ub97c \ud30c\uad34\ud558\uace0 \uad00\ub828 \ub2e8\ubc31\uc9c8\uc744 \ub9cc\ub4e4\uc9c0 \uc54a\uc2b5\ub2c8\ub2e4. \ub9c8\uce58 \uc123\ubd80\ub978 \uacb0\ub9d0\ub85c \ub9d0\uc774 \uc548 \ub418\ub294 \ucc45\uc744 \ub358\uc838\ubc84\ub9ac\uace0 "\uc61b\ub0a0 \uc61b\uc801\uc5d0, \uc885\ub9d0"\uc744 \uc77d\ub294 \uac83\ucc98\ub7fc.<\/p>\n\n\n\n\n

\ud5cc\ud305\ud2f4\uc758 \uc120\ud0dd\uc801 \ud0c0\uac9f\ud305<\/h2>\n\n\n\n\n

\ud5cc\ud305\ud2f4 \uc11c\uc5f4\ub9cc\uc744 \ud45c\uc801\uc73c\ub85c \ud558\ub3c4\ub85d \ud2b9\ubcc4\ud788 \uc124\uacc4\ub41c \ub2e4\ub978 \uc811\uadfc\ubc95\uc5d0 \ube44\ud574 PTC\uc5d0\uc11c \ud655\uc778\ub41c \uac83\uacfc \uac19\uc740 \uc2a4\ud50c\ub77c\uc774\uc2f1 \uc870\uc808\uc81c \uc57d\ubb3c\uc758 \ud55c \uac00\uc9c0 \ub2e8\uc810\uc740 "\ube44\ud45c\uc801 \ud6a8\uacfc"\uc785\ub2c8\ub2e4. HTT-C2\uc640 \uac19\uc740 \uc57d\ubb3c\uc740 "The End"\uac00 \ub2e4\ub978 \uc720\uc804\uc790\uc5d0 \uc704\uce58\ud558\ub294 \uc704\uce58\ub3c4 \ubcc0\uacbd\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \uadf8\ub7ec\ub098 \uc88b\uc740 \uc18c\uc2dd\uc740 HTT-C2\uac00 \uc800\uc6a9\ub7c9\uc5d0\uc11c \ub2e4\ub978 \uc720\uc804\uc790\ubcf4\ub2e4 \uc8fc\ub85c \ud5cc\ud305\ud2f4\uc5d0 \uc601\ud5a5\uc744 \ubbf8\uce58\ub294 \uac83\uc73c\ub85c \ubcf4\uc778\ub2e4\ub294 \uac83\uc785\ub2c8\ub2e4. \ucc98\ub9ac\ub41c \uc138\ud3ec\uc758 \ubaa8\ub4e0 \uc720\uc804\uc790\ub97c \uc870\uc0ac\ud558\uae30 \uc704\ud55c \uc2e4\ud5d8\uc774 \uc218\ud589\ub418\uc5c8\uc744 \ub54c, \uc9c0\uae08\uae4c\uc9c0 \uc0ac\uc6a9\ub41c \uac83\ubcf4\ub2e4 \ud6e8\uc52c \ub192\uc740 \uc6a9\ub7c9 \uc218\uc900\uc5d0\uc11c\ub3c4 \uad11\ubc94\uc704\ud55c \ud6a8\uacfc\uac00 \uad00\ucc30\ub418\uc9c0 \uc54a\uc558\uc2b5\ub2c8\ub2e4. \uc774\uac83\uc740 HTT-C2\uac00 \ub2e4\ub978 \uc720\uc804\uc790\uc758 \uc218\uc900\uc744 \ubcc0\uacbd\ud560 \uac00\ub2a5\uc131\uc5d0\ub3c4 \ubd88\uad6c\ud558\uace0 \ub180\ub78d\uac8c\ub3c4 \ub2e8\uc9c0 \ud5cc\ud305\ud2f4 \uc720\uc804\uc790\ub97c \uad6c\ubcc4\ud560 \uc218 \uc788\uc74c\uc744 \uc2dc\uc0ac\ud569\ub2c8\ub2e4.<\/p>\n\n\n\n\n

\ud6a8\uacfc\ub294 \uc870\uc815 \uac00\ub2a5\ud558\uace0 \ub418\ub3cc\ub9b4 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/h2>\n\n\n\n\n

\uadf8\ub7ec\ub098 \uc774\uc804\uc758 \ubaa8\ub4e0 \uc2e4\ud5d8\uc740 \uc811\uc2dc\uc758 \uc138\ud3ec\uc5d0\uc11c \uc218\ud589\ub418\uc5c8\uc2b5\ub2c8\ub2e4. \uc804\uccb4 \uc720\uae30\uccb4\uc5d0 HTT-C2\ub97c \ud22c\uc5ec\ud558\uba74 \uc5b4\ub5bb\uac8c \ub429\ub2c8\uae4c? \uac19\uc740 \ud6a8\uacfc\uac00 \uc788\ub098\uc694? \ub1cc\uc758 \ud5cc\ud305\ud2f4\uc744 \ub0ae\ucd9c \uc218 \uc788\uc2b5\ub2c8\uae4c? \uc774\ub7ec\ud55c \uc9c8\ubb38\uc5d0 \ub2f5\ud558\uae30 \uc704\ud574 PTC\uc758 \uc5f0\uad6c\uc6d0\ub4e4\uc740 HD \ub9c8\uc6b0\uc2a4 \ubaa8\ub378\ub85c \ub208\uc744 \ub3cc\ub838\uc2b5\ub2c8\ub2e4.<\/p>\n\n\n\n\n

\u201c\uc54c\uc57d\uc73c\ub85c \ud5cc\ud305\ud2f4 \uc218\uce58\ub97c \ub0ae\ucd94\ub294 \uc774 \uc0c8\ub85c\uc6b4 \uc720\ud615\uc758 \uc811\uadfc \ubc29\uc2dd\uc740 \ubcf4\ub2e4 \uce68\uc2b5\uc801\uc778 \uc811\uadfc \ubc29\uc2dd\uc5d0 \ub300\ud574 \uc8fc\uc800\ud558\ub358 \ud658\uc790\ub4e4\uc5d0\uac8c \uac8c\uc784 \uccb4\uc778\uc800\uac00 \ub420 \uc218 \uc788\uc2b5\ub2c8\ub2e4.\u201d\n\n<\/p><\/blockquote><\/figure>\n\n\n\n\n

\ub9c8\uc6b0\uc2a4\uc5d0\uac8c \ub9e4\uc77c HTT-C2\ub97c \uba39\uc600\uc2b5\ub2c8\ub2e4. \uc608, \ub2f9\uc2e0\uc740 \uadf8\uac83\uc744 \uc62c\ubc14\ub974\uac8c \uc77d\uc5c8\uc2b5\ub2c8\ub2e4. \uc950\uc5d0\uac8c \uc774 \uc57d\uc744 \uad6c\ub450\ub85c \ud22c\uc5ec\ud588\uc2b5\ub2c8\ub2e4. \uae30\uc874 \ud5cc\ud305\ud2f4 \uc800\ud558 \uce58\ub8cc\uc81c\uc640\uc758 \uc5c4\uccad\ub09c \ucc28\uc774! \ud5cc\ud305\ud2f4 \ud558\uac15 \ubd84\uc57c\ub97c \ub530\ub77c\uc628 \uc0ac\ub78c\ub4e4\uc758 \uacbd\uc6b0 \uc774\uc804 \uce58\ub8cc\ubc95\uc740 \uc694\ucd94 \ucc9c\uc790\ub098 \ub1cc \uc218\uc220\uc744 \ud544\uc694\ub85c \ud588\uc9c0\ub9cc \ub458 \ub2e4 \uc774\uc0c1\uc801\uc774\uc9c0 \uc54a\uc558\uc2b5\ub2c8\ub2e4. \uc54c\uc57d\uc73c\ub85c \ud5cc\ud305\ud2f4 \uc218\uce58\ub97c \ub0ae\ucd94\ub294 \uc774 \uc0c8\ub85c\uc6b4 \uc720\ud615\uc758 \uc811\uadfc \ubc29\uc2dd\uc740 \ubcf4\ub2e4 \uce68\uc2b5\uc801\uc778 \uce58\ub8cc\uc5d0 \ub300\ud574 \uc8fc\uc800\ud558\ub358 \ud658\uc790\ub4e4\uc5d0\uac8c \uac8c\uc784 \uccb4\uc778\uc800\uac00 \ub420 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n\n\n\n\n

\uace0\ubb34\uc801\uc73c\ub85c, \ub354 \ub9ce\uc740 HTT-C2 \uc0dd\uc950\uac00 \uc8fc\uc5b4\uc9c8\uc218\ub85d \ub354 \ub9ce\uc740 \ud5cc\ud305\ud2f4\uc774 \ub0ae\uc544\uc84c\uc2b5\ub2c8\ub2e4. \uc774\uac83\uc740 HTT-C2 \ubcf5\uc6a9\ub7c9\uc774 \ud5cc\ud305\ud2f4 \uc218\uce58\ub97c \ub0ae\ucd94\uae30 \uc704\ud574 \ub2a5\ub3d9\uc801\uc73c\ub85c \uc870\uc815\ub420 \uc218 \uc788\uc74c\uc744 \uc2dc\uc0ac\ud558\uae30 \ub54c\ubb38\uc5d0 \uc88b\uc740 \uc18c\uc2dd\uc785\ub2c8\ub2e4. \uc6b0\ub9ac\ub294 \uc778\uccb4\uc5d0 \u200b\u200b\ud574\ub86d\uc9c0 \uc54a\uace0 \uc720\uc775\ud55c \ud6a8\uacfc\ub97c \ub0b4\uae30 \uc704\ud574 \uc5bc\ub9c8\ub098 \ub9ce\uc740 \ucd1d \ud5cc\ud305\ud2f4\uc744 \ub0ae\ucd94\uc5b4\uc57c \ud558\ub294\uc9c0 \uc54c\uc9c0 \ubabb\ud558\uae30 \ub54c\ubb38\uc5d0 \uc774\uac83\uc740 \uc5c4\uccad\ub09c \uc548\uc804\uc0c1\uc758 \uc774\uc810\uc785\ub2c8\ub2e4. \ud5cc\ud305\ud2f4\uc774 \ucda9\ubd84\ud788 \ub0ae\ucd94\uc9c0 \uc54a\uc73c\uba74 \ub354 \ub9ce\uc740 \uc57d\ubb3c\uc744 \ud22c\uc5ec\ud560 \uc218 \uc788\uace0 \ud5cc\ud305\ud2f4\uc744 \ub0ae\ucd94\uba74 \ub108\ubb34 \ub9ce\uc73c\uba74 \ubcf5\uc6a9\ub7c9\uc744 \uc904\uc77c \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n\n\n\n\n

\ub610 \ub2e4\ub978 \ud765\ubbf8\ub85c\uc6b4 \ubc1c\uacac\uc740 HTT-C2\uc758 \ud6a8\uacfc\uac00 \ube60\ub974\uac8c \ub418\ub3cc\ub9b4 \uc218 \uc788\ub2e4\ub294 \uac83\uc785\ub2c8\ub2e4. \uce58\ub8cc\ub97c \uc911\ub2e8\ud55c \uc9c0 \ubd88\uacfc 10\uc77c \ud6c4\uc5d0 \ud5cc\ud305\ud2f4 \uc218\uce58\uac00 \uce58\ub8cc \uc804 \uad00\ucc30\ub41c \uc218\uc900\uc73c\ub85c \ub3cc\uc544\uac14\uc2b5\ub2c8\ub2e4. \uc774\uac83\uc740 \ub610 \ub2e4\ub978 \uc8fc\uc694 \uc548\uc804\uc0c1\uc758 \uc774\uc810\uc785\ub2c8\ub2e4. \uc774 \uc57d\ubb3c\uc758 "\uc138\ucc99"\uc774 \ub9e4\uc6b0 \ube60\ub974\uae30 \ub54c\ubb38\uc5d0 \uc57d\ubb3c\uc774 \ud658\uc790\uc758 \uc2dc\uc2a4\ud15c\uc744 \ub5a0\ub098\ub294 \ub370 \uac78\ub9ac\ub294 \uc2dc\uac04\uc774 \uc0c1\ub300\uc801\uc73c\ub85c \ube60\ub985\ub2c8\ub2e4. HTT-C2 \ud22c\uc5ec \ud6c4 \ubd80\uc815\uc801\uc778 \uacb0\uacfc\uac00 \uad00\ucc30\ub418\uba74 \ud6a8\uacfc\uac00 \ube60\ub974\uac8c \uc5ed\uc804\ub420 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \uadf8\ub7ec\ub098 10\uc77c\uc740 \uc0dd\uc950\uc758 \uc138\ucc99 \ud0c0\uc784\ub77c\uc778\uc774\uba70 \uc0ac\ub78c\ub9c8\ub2e4 \ub2e4\ub97c \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n\n\n\n\n

\ub1cc\uc640\uc2e0\uccb4\uc758\ud5cc\ud305\ud2f4\uac10\uc18c<\/h2>\n\n\n\n\n

HTT-C2 \uce58\ub8cc\ub294 \ud655\uc7a5\ub41c \uc0ac\ubcf8\ub9cc \ud45c\uc801\uc73c\ub85c \ud558\ub294 Wave Life Sciences\uc758 \ud604\uc7ac ASO \uae30\ubc18 \uc811\uadfc\ubc95\uacfc \ub2ec\ub9ac \ud655\uc7a5\ub41c \ud5cc\ud305\ud2f4 \ubc0f \ube44\ud655\uc7a5\ub41c \uc0ac\ubcf8 \ubaa8\ub450\ub97c \ud45c\uc801\uc73c\ub85c \ud569\ub2c8\ub2e4. \uc138\ud3ec \ub0b4\uc5d0\uc11c \uc815\uc0c1\uc801\uc778 \uc791\uc5c5\uc744 \uc218\ud589\ud558\ub824\uba74 \ud655\uc7a5\ub418\uc9c0 \uc54a\uc740 \ud5cc\ud305\ud2f4 \uc0ac\ubcf8\uc774 \uc5ec\uc804\ud788 \ud544\uc694\ud558\uae30 \ub54c\ubb38\uc5d0 \ub450 \uc0ac\ubcf8 \uc911 \uc5bc\ub9c8\ub098 \uac10\uc18c\ud558\ub294\uc9c0 \ucd94\uc801\ud558\ub294 \uac83\uc774 \uc911\uc694\ud569\ub2c8\ub2e4.<\/p>\n\n\n\n\n\n

\"\uc2a4\ud50c\ub77c\uc774\uc2a4
\uc2a4\ud50c\ub77c\uc774\uc2a4 \uc870\uc808\uc790\ub294 \uc720\uc804\uc801 \uc774\uc57c\uae30\ub97c \ubc14\uafc9\ub2c8\ub2e4. \ub05d\ubd80\ubd84\uc744 \uc774\ub3d9\uc2dc\ucf1c \ub354 \uc774\uc0c1 \uc138\ud3ec\uc5d0 \uc758\ubbf8\uac00 \uc5c6\uc2b5\ub2c8\ub2e4. "The End"\ub77c\ub294 \ucc45\uc744 \uc911\uac04\uc5d0 \ubc84\ub9ac\ub294 \uac83\uacfc \ub9c8\ucc2c\uac00\uc9c0\ub85c \uc138\ud3ec\ub294 \ub354 \uc774\uc0c1 \uc758\ubbf8\uac00 \uc5c6\ub294 \uc720\uc804\uc801 \uba54\uc2dc\uc9c0\ub97c \uc800\ud558\uc2dc\ud0b5\ub2c8\ub2e4.\n\n<\/figcaption><\/figure>\n\n\n\n\n

\uc5f0\uad6c\uc790\ub4e4\uc774 HTT-C2\ub97c \ud22c\uc5ec\ud55c HD \uc950\uc758 \ub1cc\ub97c \uad00\ucc30\ud588\uc744 \ub54c, \ub1cc \uc804\uccb4\uc5d0\uc11c \ud655\uc7a5\ub41c \ud5cc\ud305\ud2f4\uacfc \ube44\ud655\uc7a5\ub41c \ud5cc\ud305\ud2f4 \ubaa8\ub450 \uc57d 50% \uac10\uc18c\ub97c \ubcf4\uc558\uc2b5\ub2c8\ub2e4. \uc774\uac83\uc740 HD\uc5d0 \uac00\uc7a5 \ubbfc\uac10\ud55c \uc9c0\uc5ed\uc5d0 \ud3ec\ud568\ub418\uba70, \uc774\ub294 HTT-C2\uac00 \uac00\uc7a5 \ud544\uc694\ud55c \ubd80\ubd84\uc5d0 \ud6a8\uacfc\uac00 \uc788\uc74c\uc744 \uc2dc\uc0ac\ud569\ub2c8\ub2e4.<\/p>\n\n\n\n\n

\ud5cc\ud305\ud2f4\uc740 \ub1cc\ubfd0\ub9cc \uc544\ub2c8\ub77c \uc2e0\uccb4\uc758 \ubaa8\ub4e0 \uc138\ud3ec \uc720\ud615\uc5d0\uc11c \ubc1c\ud604\ub429\ub2c8\ub2e4. \ub530\ub77c\uc11c \uc6b0\ub9ac\ub294 \ub1cc\uc5d0\uc11c\uc758 HD\uc758 \uc601\ud5a5\uc5d0 \ub300\ud574 \uc54c\uace0 \uc788\uc9c0\ub9cc, \uadf8 \ubcc0\ud654\ub294 \uae30\ubd84 \ubcc0\ud654 \ubc0f \ubb34\ub3c4\uc99d\uacfc \uac19\uc740 \uc9c8\ubcd1\uc758 \uac00\uc7a5 \uba85\ubc31\ud55c \ubd80\ubd84\uc744 \uc81c\uc5b4\ud558\uae30 \ub54c\ubb38\uc5d0 \uc2ec\uc7a5 \ubc0f \uadfc\uc721\uacfc \uac19\uc740 \ub2e4\ub978 \uc870\uc9c1\uc5d0\ub3c4 \uc601\ud5a5\uc744 \ubbf8\uce69\ub2c8\ub2e4. \uc774 \ub54c\ubb38\uc5d0 \ub1cc\ubfd0\ub9cc \uc544\ub2c8\ub77c \ubaa8\ub4e0 \uc870\uc9c1\uc5d0\uc11c \ud5cc\ud305\ud2f4\uc744 \ub0ae\ucd94\ub294 \uac83\ub3c4 \ub3c4\uc6c0\uc774 \ub420 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n\n\n\n\n

\uc800\uc790\ub4e4\uc774 HTT-C2\uac00 \ub1cc \uc678\ubd80 \uc870\uc9c1\uc5d0\uc11c \ud5cc\ud305\ud2f4\uc744 \uc5bc\ub9c8\ub098 \ub0ae\ucdc4\ub294\uc9c0 \ud3c9\uac00\ud588\uc744 \ub54c, \uc2e4\uc81c\ub85c \ub1cc\uc5d0\uc11c\ubcf4\ub2e4 \ud6e8\uc52c \ub354 \ub192\uc558\ub2e4\ub294 \uac83\uc744 \ubc1c\uacac\ud588\uc2b5\ub2c8\ub2e4. 90% \uc774\uc0c1 \ub0ae\uc544\uc84c\uc2b5\ub2c8\ub2e4! \uc5f0\uad6c\uc5d0 \ub530\ub974\uba74 50% \uac10\uc18c\ub294 \ud5c8\uc6a9\ub418\uc9c0\ub9cc 90%\ub294 \ub108\ubb34 \ub9ce\uc744 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n\n\n\n\n

\uc548\uc804\uc0c1\uc758 \uc774\uc720\ub85c PTC\uc758 \uc5f0\uad6c\uc6d0\ub4e4\uc740 \ud654\ud559 \uad6c\uc870\ub97c \ubcc0\uacbd\ud558\uc5ec \uc57d\ubb3c\uc744 \ucd94\uac00\ub85c \uc870\uc815\ud558\uc5ec HTT-D3\ub77c\ub294 \ub610 \ub2e4\ub978 \uc57d\ubb3c\uc744 \ub9cc\ub4e4\uc5c8\uc2b5\ub2c8\ub2e4. \uc950\uc5d0\uac8c \ud22c\uc5ec\ud588\uc744 \ub54c HTT-D3\ub294 \ub1cc\uc640 \uc2e0\uccb4 \ubaa8\ub450\uc5d0\uc11c \uc57d 50%\uc758 \ub3d9\uc77c\ud55c \uc218\uc900\uc73c\ub85c \ud5cc\ud305\ud2f4\uc744 \ub0ae\ucd94\ub294 \uac83\uc73c\ub85c \ub098\ud0c0\ub0ac\uc2b5\ub2c8\ub2e4.<\/p>\n\n\n\n\n

\u201c\uc774 \ubb38\uc11c\uc758 HTT-D3 \ubc0f PTC\uc758 \uc57d\ubb3c \ubc1c\uacac \ud504\ub85c\uadf8\ub7a8\uc758 PTC-518\uacfc \uac19\uc740 \uc2a4\ud50c\ub77c\uc774\uc2a4 \uc870\uc808\uc81c\ub294 \ubaa8\ub4e0 \ud655\uc778\ub780\uc744 \uc120\ud0dd\ud558\ub294 \uac83\uc73c\ub85c \ubcf4\uc785\ub2c8\ub2e4. \ub1cc \ub0b4\ubd80\uc640 \uc678\ubd80 \ubaa8\ub450\uc5d0\uc11c \ud5cc\ud305\ud2f4\uc744 \ub0ae\ucd94\uace0, \uacbd\uad6c\ub85c \ubcf5\uc6a9\ud560 \uc218 \uc788\uc73c\uba70, \ud608\uc561 \ub1cc\ub97c \uc6b0\ud68c\ud569\ub2c8\ub2e4. \uc7a5\ubcbd\uc774\uba70, \ud5cc\ud305\ud2f4\uc5d0 \uc120\ud0dd\uc801\uc785\ub2c8\ub2e4.\u201d\n\n<\/p><\/blockquote><\/figure>\n\n\n\n\n

HD\uc758 \uc2a4\ud50c\ub77c\uc774\uc2a4 \ubcc0\uc870\uae30\uc758 \ub2e4\uc74c \ub2e8\uacc4\ub294 \ubb34\uc5c7\uc785\ub2c8\uae4c?<\/h2>\n\n\n\n\n

\uc2a4\ud50c\ub77c\uc774\uc2a4 \ubcc0\uc870\uae30\ub294 \ud5cc\ud305\ud2f4 \uc800\ud558\ub97c \uc704\ud55c \ud765\ubbf8\ub86d\uace0 \uc0c8\ub85c\uc6b4 \uc811\uadfc \ubc29\uc2dd\uc785\ub2c8\ub2e4. \uace0\ubb34\uc801\uc73c\ub85c\ub294 risdiplam\uc774\ub77c\ub294 \uc720\uc0ac\ud55c \uc57d\ubb3c\uc774 \uc774\ubbf8 FDA \uc2b9\uc778\uc744 \ubc1b\uc558\uc73c\uba70 \ud604\uc7ac \ub610 \ub2e4\ub978 \uc2e0\uacbd\ud1f4\ud589\uc131 \uc9c8\ud658\uc778 \ucc99\uc218\uc131 \uadfc\uc704\ucd95\uc99d\uc744 \uce58\ub8cc\ud558\ub294 \ub370 \uc0ac\uc6a9\ub418\uace0 \uc788\uc2b5\ub2c8\ub2e4. \uc774\uac83\uc740 \uc720\uc0ac\ud55c \uac83\uc774 HD\ub97c \uce58\ub8cc\ud558\ub294 \ub370 \uc0ac\uc6a9\ub420 \uc218 \uc788\ub294 \uac00\ub2a5\uc131\uc744 \uac15\ud654\ud569\ub2c8\ub2e4.<\/p>\n\n\n\n\n

HTT-D3\uac00 \uc774 \ubc31\uc11c\uc5d0\uc11c \uac1c\ub150 \uc99d\uba85 \uc57d\ubb3c\ub85c \uc0ac\uc6a9\ub418\uc5c8\uc9c0\ub9cc PTC Therapeutics\ub294 \ud30c\uc774\ud504\ub77c\uc778\uc744 \uc0ac\uc6a9\ud558\uc5ec \ub2e4\ub978 \uc57d\ubb3c\uc744 \ubc1c\uacac\ud558\uc5ec \uc55e\uc73c\ub85c \ub098\uc544\uac00\uace0 \uc788\uc2b5\ub2c8\ub2e4. \uc774 \uc57d\uc744 PTC-518\uc774\ub77c\uace0 \ud569\ub2c8\ub2e4. HD\uac00 \uc544\ub2cc \uac1c\uc778\uc744 \ub300\uc0c1\uc73c\ub85c \ud55c PTC-518\uc5d0 \ub300\ud55c 1\uc0c1 \uc548\uc804\uc131 \uc2dc\ud5d8\uc774 \uc9c4\ud589 \uc911\uc774\uc9c0\ub9cc \uc911\uac04 \uacb0\uacfc\uc5d0 \ub530\ub974\uba74 \uc2dc\ud5d8\uc774 \uc798 \uc9c4\ud589\ub418\uace0 \uc788\uc2b5\ub2c8\ub2e4. \uc9c0\uae08\uae4c\uc9c0 \uc57d\ubb3c\uc740 \ubd80\uc791\uc6a9 \uc5c6\uc774 \uc798 \ub0b4\uc57d\ub418\uc5c8\uc2b5\ub2c8\ub2e4. Huntingtin\uc740 \uc57d\ubb3c\uc5d0 \uc758\ud574 \uad00\uc5ec\ub418\uace0 \uc788\uc73c\uba70 \ub9c8\uc6b0\uc2a4 \ubaa8\ub378\uc5d0\uc11c \uad00\ucc30\ub41c \uac83\uacfc \uc720\uc0ac\ud55c \uc6a9\ub7c9 \uc758\uc874\uc801 \ubc29\uc2dd\uc73c\ub85c \ubc1c\ud604\uc774 \uac10\uc18c\ud558\uace0 \uc788\uc2b5\ub2c8\ub2e4. HD \ud658\uc790\uc5d0 \ub300\ud55c 2\uc0c1 \uc2dc\ud5d8\uc740 2022\ub144 \ub9d0\uc5d0 \uc2dc\uc791\ub420 \uc608\uc815\uc785\ub2c8\ub2e4.<\/p>\n\n\n\n\n

\uc774 \ubb38\uc11c\uc758 HTT-D3 \ubc0f PTC\uc758 \uc57d\ubb3c \ubc1c\uacac \ud504\ub85c\uadf8\ub7a8\uc758 PTC-518\uacfc \uac19\uc740 \uc2a4\ud50c\ub77c\uc774\uc2a4 \uc870\uc808\uc81c\ub294 \ubaa8\ub4e0 \ud655\uc778\ub780\uc744 \uc120\ud0dd\ud558\ub294 \uac83\uc73c\ub85c \ubcf4\uc785\ub2c8\ub2e4. \ub1cc \ub0b4\ubd80\uc640 \uc678\ubd80 \ubaa8\ub450\uc5d0\uc11c \ud5cc\ud305\ud2f4\uc744 \ub0ae\ucd94\uace0, \uacbd\uad6c\ub85c \ubcf5\uc6a9\ud560 \uc218 \uc788\uc73c\uba70, \ud608\uc561 \ub1cc\ub97c \uc6b0\ud68c\ud569\ub2c8\ub2e4. \uc7a5\ubcbd\uc774\uba70, \ud5cc\ud305\ud2f4\uc5d0 \uc120\ud0dd\uc801\uc785\ub2c8\ub2e4. HD \uc5f0\uad6c\uc5d0 \uc788\uc5b4 \ud798\ub4e0 \uc18c\uc2dd\uc774 \uc788\ub294 \ud55c \ud574 \ub3d9\uc548 \uc0ac\uc2e4\uc774\ub77c\uace0 \ud558\uae30\uc5d0\ub294 \ub108\ubb34 \uc88b\uc740 \uac83 \uac19\uc2b5\ub2c8\ub2e4. \uadf8\ub7ec\ub098 \ud604\uc7ac \ub370\uc774\ud130\ub294 \ub9e4\uc6b0 \uc720\ub9dd\ud574 \ubcf4\uc774\uba70 HD \ucee4\ubba4\ub2c8\ud2f0\ub294 \uba87 \uac00\uc9c0 \uc720\ub9dd\ud55c \ub274\uc2a4\ub97c \uc5f4\ub9dd\ud558\uace0 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n\n\n","protected":false},"excerpt":{"rendered":"

PTC Therapeutics\uc758 \uc5f0\uad6c\uc6d0\ub4e4\uc740 \ucd5c\uadfc \ud765\ubbf8\ub85c\uc6b4 \uc0c8\ub85c\uc6b4 \ubc1c\uacac, \uc989 \uc54c\uc57d\uc73c\ub85c \ubcf5\uc6a9\ud560 \uc218 \uc788\ub294 \uc720\ub9dd\ud55c \uc0c8\ub85c\uc6b4 \ud5cc\ud305\ud2f4 \uc800\ud558 \uc57d\ubb3c\uc744 \ubc1c\ud45c\ud588\uc2b5\ub2c8\ub2e4. \uc774\uac83\uc740 \uc6b0\ub9ac\uac00 \ud5cc\ud305\ud2f4 \uc218\uce58\ub97c \ub0ae\ucd94\ub294 \ubc29\ubc95\uc744 \ubc14\uafc0 \uac83\uc785\ub2c8\uae4c?<\/p>\n","protected":false},"author":1,"featured_media":20385,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":""},"categories":[884,885],"class_list":["post-18096","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category---2","category-885"],"jetpack_featured_media_url":"https:\/\/i0.wp.com\/ko.hdbuzz.net\/wp-content\/uploads\/2022\/01\/codev-2022-01-25-0fb40d899f-fairy_tale_book-scaled.jpg?fit=2560%2C1707&quality=89&ssl=1","acf":{"writers":[{"ID":4201,"user_firstname":"Sarah","user_lastname":"Hernandez","nickname":"Dr Sarah Hernandez","user_nicename":"sarahhernandez","display_name":"Dr Sarah Hernandez","user_email":"sjherna2@uci.edu","user_url":"","user_registered":"2025-05-12 17:22:01","user_description":"Dr. Sarah Hernandez is the Director of Research Programs at the Hereditary Disease Foundation (HDF). She carried out her postdoctoral work with Dr. Leslie Thompson at the University of California, Irvine, where she used stem cells and fruit flies to define HD-related changes that exist outside the cell, in the \u201cextracellular matrix\u201d. At the HDF, Sarah oversees the Foundation\u2019s scientific research portfolio by managing the grants program, acting as the scientific liaison, and coordinating scientific programming through webinars, workshops, and conferences. Sarah enthusiastically supports the mission of the HDF, to identify the most promising research and accelerate treatments for Huntington\u2019s disease.","user_avatar":""},{"ID":4001,"user_firstname":"Jeff","user_lastname":"Carroll","nickname":"Dr Jeff Carroll, PhD","user_nicename":"jeffcarroll","display_name":"Dr Jeff Carroll, PhD","user_email":"jcarroll42@gmail.com","user_url":"","user_registered":"2025-05-12 17:21:43","user_description":"Jeff is an Associate Professor in the Department of Neurology at the University of Washington, Seattle, USA. Throughout his academic career, Jeff\u2019s focus has been on better understanding, and ultimately trying to help treat, patients with Huntington\u2019s Disease. In 2003, genetic testing revealed that Jeff had inherited a mutant copy of the Huntington\u2019s disease gene from his mother, which means that in the absence of new treatments, he will eventually develop symptoms. In addition to his work in the lab, Jeff is deeply involved in rare disease community work. In 2011, he founded HDBuzz, the first internet news platform for HD patients and their families worldwide.","user_avatar":""}],"editors":[{"ID":4202,"user_firstname":"Rachel","user_lastname":"Harding","nickname":"Dr Rachel Harding","user_nicename":"rachelharding","display_name":"Dr Rachel Harding","user_email":"rachel.harding@utoronto.ca","user_url":"","user_registered":"2025-05-12 17:22:01","user_description":"Rachel Harding is an Assistant Professor at the Department of Pharmacology and Toxicology and a Principal Investigator at the Structural Genomics Consortium. Rachel completed her undergraduate and DPhil in structural biology at the University of Oxford, before moving to the University of Toronto for her postdoctoral training. A key focus of Rachel\u2019s research is the huntingtin protein, mutated in people with Huntington\u2019s disease. Huntington\u2019s is a devastating, incurable, genetic, neurodegenerative disease caused by a CAG-tract expansion in the Huntingtin gene. Rachel studies the structure-function of the huntingtin protein in both its wildtype and disease forms, with a view to better understand the mechanisms of disease, as well as trying to find new avenues of therapeutic intervention.","user_avatar":""}],"translators":[4178],"sources":null,"conflicts":"\uc800\uc790\ub294 \ubb38\uc81c\uac00 \ub420 \uc774\ud574\uad00\uacc4\ub97c \uac00\uc9c0\uc9c0 \uc54a\uc2b5\ub2c8\ub2e4. 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