{"id":41308,"date":"2023-05-10T07:50:51","date_gmt":"2023-05-10T14:50:51","guid":{"rendered":"https:\/\/idthefuture.com\/?p=41308"},"modified":"2024-10-15T14:00:22","modified_gmt":"2024-10-15T21:00:22","slug":"1747","status":"publish","type":"post","link":"https:\/\/idthefuture.com\/1747\/","title":{"rendered":"Could Blind Forces Build a Self-Replicating Molecule? \u00a0"},"content":{"rendered":"\n<p>On today\u2019s <strong>ID the Future<\/strong>, scientist and <em><a rel=\"noreferrer noopener\" href=\"https:\/\/www.amazon.com\/dp\/1734183705\/\" target=\"_blank\">Stairway to Life<\/a><\/em> co-author Rob Stadler and host Eric Anderson examine a recent PNAS paper on origin of life, <a rel=\"noreferrer noopener\" href=\"https:\/\/www.pnas.org\/doi\/full\/10.1073\/pnas.1914282117\" target=\"_blank\">\u201cAn RNA Polymerase Ribozyme that Synthesizes Its Own Ancestor.\u201d<\/a> A superficial look at the paper\u2014and the paper\u2019s title in particular\u2014might give the impression that the laboratory findings behind the paper render the blind evolution of the first self-replicating biological system appreciably more plausible. Not so fast, says Stadler. Listen in as he and Anderson highlight various ways the laboratory work in question is wildly unrealistic. And for a video exploring the many problems involved in blindly evolving the first self-replicator, check out a new Long Story Short animated YouTube video, created with input from Stadler, <em><a rel=\"noreferrer noopener\" href=\"https:\/\/www.youtube.com\/watch?v=wyDEfEMIzIQ\" target=\"_blank\">Debunking RNA world: Replication &amp; Chemical Evolution<\/a><\/em>.<\/p>\n","protected":false},"excerpt":{"rendered":"On today\u2019s ID the Future, scientist and Stairway to Life co-author Rob Stadler and host Eric Anderson examine a recent PNAS paper on origin of life, \u201cAn RNA Polymerase Ribozyme that Synthesizes Its Own Ancestor.\u201d A superficial look at the paper\u2014and the paper\u2019s title in particular\u2014might give the impression that the laboratory findings behind the paper render the blind evolution of the first self-replicating biological system appreciably more plausible. Not so fast, says Stadler. Listen in as he and Anderson highlight various ways the laboratory work in question is wildly unrealistic. And for a video exploring the many problems involved in blindly evolving the first self-replicator, check out a new Long Story Short animated YouTube video, created with input from<a class=\"ellipsis article-more\" href=\"https:\/\/idthefuture.com\/1747\/\"><span> Read More &rsaquo;<\/span><\/a>","protected":false},"author":150,"featured_media":41309,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_editorskit_title_hidden":false,"_editorskit_reading_time":0,"_editorskit_is_block_options_detached":false,"_editorskit_block_options_position":"{}","sync_status":"synced","episode_type":"audio","audio_file":"https:\/\/episodes.castos.com\/id\/23557f91-85a5-460c-8422-c88aa6c670d5-IDTF-1747-RobStadler-Self-Replication.mp3","podmotor_file_id":"1296085","podmotor_episode_id":"1475257","castos_file_data":"","cover_image":"","cover_image_id":"","duration":"00:34:27","filesize":"21.6 mb","filesize_raw":"22673020","date_recorded":"2023-05-10 07:50:51","explicit":"","block":"","itunes_episode_number":"1747","itunes_title":"","itunes_season_number":"","itunes_episode_type":"full","footnotes":""},"categories":[],"tags":[2696,275,6682,6677,4208,6681,4703,6680,1137,5424,6679,3820,3143,3950,6678],"series":[7227],"speaker":[],"class_list":["post-41308","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","tag-abiogenesis","tag-chemical-evolution","tag-david-p-horning","tag-gerald-f-joyce","tag-jack-szostak","tag-katrina-f-tjhung","tag-long-story-short","tag-maxim-n-shokhirev","tag-origin-of-life","tag-ribozyme","tag-rna-polymerase-ribozyme","tag-self-replicating-machines","tag-self-replicating-molecule","tag-self-replication","tag-simple-self-replicator","series-intelligent-design-the-future"],"acf":[],"author_names":["Rob Stadler"],"episode_featured_image":"https:\/\/idthefuture.com\/wp-content\/uploads\/sites\/4\/2023\/05\/mole-scaled.jpg","episode_player_image":"https:\/\/idthefuture.com\/wp-content\/uploads\/sites\/4\/2021\/08\/idthefuture-cover.jpg","download_link":"https:\/\/op3.dev\/e\/idthefuture.com\/podcast-download\/41308\/1747.mp3","player_link":"https:\/\/op3.dev\/e\/idthefuture.com\/podcast-player\/41308\/1747.mp3","audio_player":"<audio class=\"wp-audio-shortcode\" id=\"audio-41308-1\" preload=\"none\" style=\"width: 100%;\" controls=\"controls\"><source type=\"audio\/mpeg\" src=\"https:\/\/op3.dev\/e\/idthefuture.com\/podcast-player\/41308\/1747.mp3?_=1\" \/><a href=\"https:\/\/op3.dev\/e\/idthefuture.com\/podcast-player\/41308\/1747.mp3\">https:\/\/op3.dev\/e\/idthefuture.com\/podcast-player\/41308\/1747.mp3<\/a><\/audio>","episode_data":{"playerMode":"dark","subscribeUrls":[],"rssFeedUrl":"https:\/\/idthefuture.com\/feed\/podcast\/intelligent-design-the-future","embedCode":"<blockquote class=\"wp-embedded-content\" data-secret=\"ktLdDhpHSv\"><a href=\"https:\/\/idthefuture.com\/1747\/\">Could Blind Forces Build a Self-Replicating Molecule? \u00a0<\/a><\/blockquote><iframe sandbox=\"allow-scripts\" security=\"restricted\" src=\"https:\/\/idthefuture.com\/1747\/embed\/#?secret=ktLdDhpHSv\" width=\"500\" height=\"350\" title=\"&#8220;Could Blind Forces Build a Self-Replicating Molecule? \u00a0&#8221; &#8212; ID the Future\" data-secret=\"ktLdDhpHSv\" frameborder=\"0\" marginwidth=\"0\" marginheight=\"0\" scrolling=\"no\" class=\"wp-embedded-content\"><\/iframe><script type=\"text\/javascript\">\n\/* <![CDATA[ *\/\n\/*! 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