{"id":41148,"date":"2023-03-06T12:03:56","date_gmt":"2023-03-06T20:03:56","guid":{"rendered":"https:\/\/idthefuture.com\/?p=41148"},"modified":"2024-10-15T14:00:29","modified_gmt":"2024-10-15T21:00:29","slug":"1719","status":"publish","type":"post","link":"https:\/\/idthefuture.com\/1719\/","title":{"rendered":"Jonathan Bartlett on the Growing Evidence of Designed Mutations"},"content":{"rendered":"\n

On today\u2019s ID the Future<\/strong>, host and evolutionary biologist Jonathan McLatchie sits down with software R&D engineer Jonathan Bartlett to discuss Bartlett\u2019s work on the question of when genetic mutations are random versus directed. Bartlett explains that the issue isn\u2019t an all-or-nothing affair. Often a given biological system dramatically limits the search space of possible mutations in useful ways, and then within that much more limited set of possible mutations, random processes are at play. He gives the example of antibody mutations. He argues that many biological systems show considerable evidence of having been beneficially designed for directed mutations. Why, then, are many mutations deleterious? He also has an answer for that. Tune in to learn more.<\/p>\n\n\n\n

Bartlett\u2019s two peer-reviewed papers mentioned in this podcast are here<\/a> and here<\/a>. If you want to further benefit from Bartlett\u2019s knack for making complex ideas accessible, check out his videos<\/a> at the Blyth Institute.<\/p>\n","protected":false},"excerpt":{"rendered":"On today\u2019s ID the Future, host and evolutionary biologist Jonathan McLatchie sits down with software R&D engineer Jonathan Bartlett to discuss Bartlett\u2019s work on the question of when genetic mutations are random versus directed. Bartlett explains that the issue isn\u2019t an all-or-nothing affair. Often a given biological system dramatically limits the search space of possible mutations in useful ways, and then within that much more limited set of possible mutations, random processes are at play. He gives the example of antibody mutations. He argues that many biological systems show considerable evidence of having been beneficially designed for directed mutations. Why, then, are many mutations deleterious? He also has an answer for that. Tune in to learn more. Bartlett\u2019s two peer-reviewed Read More ›<\/span><\/a>","protected":false},"author":17,"featured_media":41149,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_editorskit_title_hidden":false,"_editorskit_reading_time":1,"_editorskit_is_block_options_detached":false,"_editorskit_block_options_position":"{}","sync_status":"synced","episode_type":"audio","audio_file":"https:\/\/episodes.castos.com\/id\/2e5ae117-432b-493e-b66f-7a240034e3c9-IDTF-1719-JonathanMcLatchie-JonathanBartlett-Mutations.mp3","podmotor_file_id":"1246540","podmotor_episode_id":"1430008","castos_file_data":"","cover_image":"","cover_image_id":"","duration":"00:25:14","filesize":"14.9 mb","filesize_raw":"15661088","date_recorded":"2023-03-06 12:03:56","explicit":"","block":"","itunes_episode_number":"1719","itunes_title":"","itunes_season_number":"","itunes_episode_type":"full","footnotes":""},"categories":[],"tags":[],"series":[7227],"speaker":[],"class_list":["post-41148","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","series-intelligent-design-the-future"],"acf":[],"author_names":["Jonathan Bartlett"],"episode_featured_image":"https:\/\/idthefuture.com\/wp-content\/uploads\/sites\/4\/2023\/03\/antibodies-scaled.jpg","episode_player_image":"https:\/\/idthefuture.com\/wp-content\/uploads\/sites\/4\/2021\/08\/idthefuture-cover.jpg","download_link":"https:\/\/op3.dev\/e\/idthefuture.com\/podcast-download\/41148\/1719.mp3","player_link":"https:\/\/op3.dev\/e\/idthefuture.com\/podcast-player\/41148\/1719.mp3","audio_player":"https:\/\/op3.dev\/e\/idthefuture.com\/podcast-player\/41148\/1719.mp3<\/a><\/audio>","episode_data":{"playerMode":"dark","subscribeUrls":[],"rssFeedUrl":"https:\/\/idthefuture.com\/feed\/podcast\/intelligent-design-the-future","embedCode":"

Jonathan Bartlett on the Growing Evidence of Designed Mutations<\/a><\/blockquote>