Basic mechanisms of oxygen homeostasis (Edurne Berra & Brian Ortmann)

• Sonia Rocha, University of Liverpool: Oxygen-dependent PHD1-mediated prolyl hydroxylation in controlling progression through mitosis
• Alexey Shapiguzov, University of Helsinki: Mitochondria affect photosynthesis through altered tissue levels of O₂
• Jing Zhang, University of Wuhan: Hypoxia-induced alteration in chromatin looping

Flash talks: Plus 2-3 selected from abstracts

Short Break

Hypoxia in developmental and regenerative biology (Christian Stockmann & Carsten Scholz)

• Can Aztekin, Max Planck Institute, Tübingen: The role of hypoxia on limb development and regeneration in axolotl and tadpoles.
• Katrien de Boeck/Jess Snedeker, ETH, Zurich: The role of HIFs in tendinopathy
  and tendon regeneration.
• Philipp Lehmann, Greifswald: Hypoxia on insect development (including beetles and
  butterflies), specifically on diapause, and energy metabolism.

Flash talks: Plus 2-3 selected from abstracts

Poster Session Lunch (all posters)

Oxygen sensing as a regulator of inflammation (Peter Mirtschink and Ben Wielockx)

• Sarah Walmsley, Edinburgh, UK: Reprogramming the Neutrophil
• Emily DeMichele, Dublin, Ireland: The impact of HIF1 during cancer-specific metabolic
  adaptations
• Christa Maes, Leuven, Belgium: Pharmacological HIF activation protects against diet-induced obesity and skeletal dysfunction

Flash talks: Plus 2-3 selected from abstracts

Short Break

Keynote #2 Speaker tbc

End Of The Day

Metabolic Consequences of Hypoxia (Cormac Taylor & Raphael Fagundes Rosa)

• Yoshi Henning, Essen, Germany: Targeting hypoxia-inducible factor-1 in cell death and
  metabolic dysregulation.
• Brian Ortmann, Newcastle, UK: Chromatin modifications in hypoxia
• Marcos Aurelio Ramirez Vitolo, São Paulo, Brazil: HIF-1 and the Gut Microbiome
• Edurne Berra, CIC BioGUNE, Derio, Spain: Decoding Hypoxia’s Metabolic Fingerprint Through Polyamines

Flash talks: Plus 2 selected from abstracts

Short Break

Hypoxia response and therapeutic indications (Johanna Myllyharju & Peppi Karppinen)

• Betty Gardie, University of Nantes: Study of hypoxia-related genes associated with hereditary erythrocytosis
• Dörthe Katschinski, University of Göttingen: Compartment-specific hydrogen peroxide
  production in cardiomyocyte redox signaling and function
• Peppi Karppinen (Koivunen): Cardiometabolic outcomes of roxadustat in healthy volunteers

Flash talks: Plus 2-3 selected from abstracts

Poster Session Lunch (all posters)

Innate and adaptive immunity (Sandra Winning and Brenda Krishnacoumar)

• Kami Pekayvaz, Munich: Hypoxic monocytes acquire a HIF1a-mediated thrombus resolving profile
• Hannah Sperber, Essen: Hypoxic CD73 surface expression of HIV latently infected CD4 + T-cells
• Aline Bozec, Erlangen: HIF signaling pathways affecting adaptive immune responses, inflammation, and bone homeostasis

Flash talks: Plus 2-3 selected from abstracts

Short Break

Rapid oxygen sensing and hypoxia pathway cancers (Tammie Bishop)

• James Nathan, University of Cambridge: Insights into HIF dependent and independent
  signaling
• Tom Keeley, University of Oxford: Oxygen homeostasis – new insights into an ancient problem
• Rodrigo Toledo, CNIS: The interplay between genetics and environment in hypoxia pathway tumors

Flash talks: Plus 2 selected from abstracts

Closing remarks by Sir Peter J. Ratcliffe

Social Hour

End Of The Day