Self-Amplifying RNA

In August 2020, BioNtech published an Investigator's brochure - BioNtech August 2020 - see p 13 - in which they described the development of 3 different vaccine platforms labelled a, b and c -

• BNT162a : Uridine mRNA
• BNT162b : Nucleoside modified mRNA
• BNT162c : Self-amplifying mRNA

BNT162c is noted for having a "long duration of protein expression"

In November 2020, BioNTech published a report.

BionTech November 2020 : see p 10

• non-modified uridine containing mRNA (uRNA),
• nucleoside-modified mRNA (modRNA) and
• self amplifying RNA (saRNA)

There were ongoing clinical trials using self-amplifying COVID 19 "vaccines" with human subjects. One of these trials was with 500 subjects in Germany. This was a phase 2 trial, and its completion date was set for April 2023.. This is the type of vaccine that they plan to release next. Evidence outlined below suggests that they may have already released it on a small scale in 7 states of the USA. It is reasonable to assume that they want to release it on a larger scale soon. This is the next phase.

What are these 3 types of vaccine, and how do they differ in effects ?

1. Non-modified uridine containing RNA (uRNA) : RNA consists of a string of letters A C U or G. Where A = adenine, C = Cysteine, U = Uridine and G = Guanine. Non=modified RNA (uRNA) contains these 4 letters. Our innate immune system can detect non-modified RNA and destroy it.


2. Nucleoside Modified RNA (modRNA) : In this RNA, the Uridine is replaced with Pseudo-Uridine, so our immune system can nolonger detect it.


3. Self-amplifying RNA (saRNA) : Self-amplifying mRNA (saRNA) vaccines are similar to conventional mRNA vaccines, with the exception, that saRNA vaccines also self-replicate their mRNA. The self-amplifying mRNA has two open reading frames. The first open reading frame, like conventional mRNA, codes for the antigen protein of interest. The second open reading frame codes for an RNA-dependent RNA polymerase (and its helper proteins) which self-replicates the mRNA construct in the cell and creates multiple self-copies. Wiki. Self replicating RNA generates 64 times the amount of antigen (spike) compared to non-amplifying RNA, and as a consequence produces a much stronger immunogenic response - see - Study. Besides producing more antigen, self-amplifying RNA produces antigen over a longer time. See - Study

An exponential increase without limit?

With self-amplifying RNA, the RNA codes for the Spike protein, but also codes for a polymerase that then produces a copy of the RNA molecule. The process then repeats exponentially. But what stops the process? If it is self-amplifying but not self-stopping, then we would expect an unceasing production of spike protein over time, causing continuous and cumulative damage until organ failure results. There does not seem to be any internal control limiting production of the Spike. This would mean that the effect of self-amplifying RNA is equivalent to taking repeated doses indefinitely !

From the manufacturer's point of view BNT162c requires less initial dosage, but due to self-amplification within the body, the eventual amount of circulating spike protein may be much higher than with BNT162b. It undergoes an exponential increase where the circulating spike amount doubles each time - 2 raised to the power n

This paper - here states that self-amplifying vaccines can replicate for upto 2 months.

Here are 2 videos by Doctors for Covid Ethics -

VIDEO 1 : Self Amplifying Vaccines

VIDEO 2 : Self Amplifying Vaccines

How Much Self Amplifying Vaccine is Necessary to Flood Your Circulation with Spikes?

If each mRNA codes for an antigen + the enzymes necessary to replicate the mRNA 100 times, and then those mRNAs themselves go on to produce 100 antigens + the enzymes necessary to replicate each of the 100 mRNAs 100 times, you can see that the tinest amount of self-amplifying RNA could flood your circulation with spike proteins. It does not have to be as much as a single injection or even a single drop from that injection. The tinest amount getting into your system would be effective.

In addition to generating a higher spike load, self amplifying vaccines may facilitate "shedding". This is because it would only take a tiny amount of the mRNA to transfer from a close contact to just one of your cells, and the multiplication effect would ensure your complete infection

Given the microscopic amount needed to infect, it is also important to avoid any invasive medical procedure where you suspect harmful intent, i.e - nasal swabbing, or any other coerced medical treatment. For example, as a student of pharmaceutical science, I learned about solvents that can penetrate the dermal layers of skin carrying a payload of active ingredients. If such a solvent were carrying LNPs containing saRNA, and a drop of this was applied to a nasal swab....

How Long Does it Take for Each Cycle of Replication

Since the number of deaths and injuries are proportional to the concentration of spike proteins, then we can determine the replication time from the time taken for deaths to double.

Making Sense of the Vaccine Drug Profiles for Different States in the USA

We can now look at profiles for different states showing the vaccine drug effect plotted against time. For most states, the profile shows deaths concentrated into a short time following vaccination, with deaths tappering off quickly as each day passes after vaccination. This would be expected with BNT162b, since the body metabolises and excretes the drug, so its concentration is decreasing with time. Since the concentration of the drug determines its effect (number of deaths), consequently the number of deaths decreases rapidly with time - following an exponential decrease.

However, some states (MI, TX, FL, TN, KY, MN, GA) have a more extended response to the vaccines - deaths occur with greater frequency, and over a longer time period of about 6 months, When we look at the profile for these states, we see that it more closely resembles a straight line - suggesting that the rate of deaths does not change over time - which inturn suggests that the concentration of the toxin remains constant over time. Presumably the toxin is being metabolised and excreted, so its persistence over time must be due to it being regenerated and replaced. This would be expected with BNT162c. Consequently, it is proposed that in the States of MI, TX, FL, TN, KY, MN and GA, selfamplifying vaccines have been deployed. This would account for both the higher frequency, and extending duration of deaths

The effect of a self-amplified vaccine would be the same as constant re-exposure to the toxin. Since each exposure generates damage, it follows that damage will increase with time until it eventuates in organ collapse and death. Injury and death reach a maximum at 180 days, so it may be the case that self-amplifying vaccines are only active for 6 months. So taking a booster every 6 months would ensure the continuance of damage.

Summary

So, on the very eve of release of the vaccine in November 2020, BioNtech were working on these 3 platforms - some of the vaccines would be uRNA , some would be modRNA , and some would be saRNA .

• Nucleoside-modified RNA (modRNA), is so modified to evade the innate immune system, by replacing uridine with pseudo-uridine - something which renders the foreign mRNA invisible to our natural defences.
• Self-amplifying RNA (saRNA) turns the body into a factory for yet more mRNA, causing the body to generate the toxic spike protein over a longer period. Those states unlucky enough to get the saRNA would experience prolonged exposure to the toxin, and consequently an elevated number of deaths.

So you can see, just from this alone, that not all vaccines are equal - there are at least 3 types developed. One (modRNA) can evade your defences, and the other (saRNA) can reproduce itself, so even if some are caught by your defences they are simply replaced by more. You can think of these 3 types of vaccines as 3 different soldiers - the first soldier is invisible to your defences, and the second can clone or multiply itself. It is immediately obvious that these 3 types of vaccine could result very different levels of fatality.

Jessica Rose Article

Jessica Rose has written an article on this subject that can be viewed here -

When you hear BNT162c(2), run, don't walk, RUN away.

Here is an interview between Jessica and a scientist developing saRNA. The scientist admits that the dose of RNA is proportional to the number of adverse reactions experienced, and that saRNA is able to multiply itself 100 times (thereby requiring a lower initial dose)

Interview

Trials of self amplifying vaccines were completed in 2023. However, the antigen that they are going to inject you with is being kept a secret - just look at the blacked out areas in their report !

You can see this for yourself (or rather not see this for yourself) here - https://www.tga.gov.au/sites/default/files/foi-2183-09.pdf Page 18

They are not going to tell you what the encoded antigen is, but they are going to insist that you are injected with it. Neither are they going to provide any safety data (this has also been blacked out)

Once again, you can see this for yourself (or rather not see this for yourself) here - https://www.tga.gov.au/sites/default/files/foi-2183-09.pdf. Page 62

A warning from Pfizer's Ex-head of Research and Development

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