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Inside PCWG4: How New Biomarkers and Imaging Criteria Are Shaping Prostate Cancer Research

Andrew Armstrong, MD, of Duke University Cancer Center, discusses new guidelines from Prostate Cancer Working Group 4, including the main drivers that necessitated the update, and how the new recommendations incorporate emerging biomarkers and data.

Dr. Armstrong also elaborates on new imaging-specific rPFS criteria and updated intervals for imaging, and what he believes are the most critical areas that need a coordinated effort to support the next generation of prostate cancer trials.

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Precision, Partnership, Progress: UCSF’s Unique Multidisciplinary Approach to Bladder Cancer

A multidisciplinary team of clinicians and scientists—under the auspices of the University of California, San Francisco Helen Diller Family Comprehensive Cancer Center—is redefining what is possible for patients with both muscle-invasive and non–muscle-invasive bladder cancer.

Leveraging breakthroughs in genomic profiling, molecular imaging, and immunotherapy, UCSF is moving beyond traditional treatment paradigms and toward a model grounded in precision medicine.

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65-year-old man presented after outside ultrasound. Hx: 'Known left renal agenesis. Query mass lesion on lower pole of right kidney. ?Renal cancer?' ...

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Karine Tawagi, MDRenal Cell Carcinoma | March 25, 2026

Drs. Tawagi and Armstrong recap promising belzutifan data in RCC and early cabo activity in refractory germ cell tumors.

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Karine Tawagi, MDUrothelial Carcinoma | March 25, 2026
Drs. Tawagi and Armstrong highlight EV/pembro’s perioperative results and emerging HER2‑targeted options in bladder
Karine Tawagi, MDProstate Cancer | March 25, 2026

Drs. Tawagi and Armstrong review prostate trials on radium combos, PARP strategies, and optimal ADT duration.

Yousef Zakharia, MDMuscle Invasive Urothelial Carcinoma | March 16, 2026

Dr. Yousef Zakharia discusses a study on utilizing ctDNA as a biomarker of response to EV/pembro in MIBC.

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