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Latest Abstracts Imported from Pubmed.gov, Rated & Indexed

Pectic polysaccharides from Radix Sophorae Tonkinensis exhibit significant antioxidant effects.

Article Published Date : Jun 14, 2021
Study Type : In Vitro Study
Additional Links
Substances : Flavonoids : CK(5388) : AC(2571)
Diseases : Oxidative Stress : CK(16277) : AC(6418)
Pharmacological Actions : Antioxidants : CK(37158) : AC(15601)
Additional Keywords : Polysaccharides : CK(1558) : AC(872)

Radix Sophorae Flavescentis of Sophora flavescens Aiton inhibits LPS-induced macrophage pro-inflammatory response via regulating CFHR2 expression.

Article Published Date : Sep 14, 2024
Study Type : In Vitro Study
Additional Links
Diseases : Inflammation : CK(17174) : AC(5905), Lipopolysaccharide-Induced Toxicity : CK(3501) : AC(2042)
Pharmacological Actions : Anti-Inflammatory Agents : CK(43242) : AC(17300), Cyclooxygenase 2 Inhibitors : CK(2369) : AC(1395), Interleukin-6 Downregulation : CK(10137) : AC(3937), Postaglandin PGE2 downregulation : CK(403) : AC(208), Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(12620) : AC(5195)
Additional Keywords : Plant Extracts : CK(19604) : AC(7177)

Effects of sophoraflavanone G, a prenylated flavonoid from Sophora flavescens, on cyclooxygenase-2 and in vivo inflammatory response.

Article Published Date : May 31, 2002
Study Type : In Vitro Study
Additional Links
Substances : Flavonoids : CK(5388) : AC(2569), Sophora Flavescens : CK(167) : AC(80)
Diseases : Inflammation : CK(17174) : AC(5905), Lipopolysaccharide-Induced Toxicity : CK(3501) : AC(2042)
Pharmacological Actions : Anti-Inflammatory Agents : CK(43242) : AC(17300), Cyclooxygenase 2 Inhibitors : CK(2369) : AC(1395), Cyclooxygenase Inhibitors : CK(86) : AC(45)

Quick identification of kuraridin, a noncytotoxic anti-MRSA (methicillin-resistant Staphylococcus aureus) agent from Sophora flavescens.

Article Published Date : Dec 31, 2011
Study Type : In Vitro Study
Additional Links
Substances : Flavonoids : CK(5388) : AC(2569), Sophora Flavescens : CK(165) : AC(78)
Diseases : Staphylococcus aureus: Methicillin-resistant (MRSA) : CK(498) : AC(280)
Pharmacological Actions : Anti-Bacterial Agents : CK(4480) : AC(2136)
Additional Keywords : Plant Extracts : CK(19604) : AC(7176)

Kuraridin has the potential to be an alternative antivirulence option for reducing MRSA pathogenicity.

Article Published Date : Feb 23, 2025
Study Type : In Vitro Study
Additional Links
Substances : Flavonoids : CK(5388) : AC(2568), Sophora Flavescens : CK(165) : AC(78)
Diseases : Staphylococcus aureus: Methicillin-resistant (MRSA) : CK(498) : AC(280)
Pharmacological Actions : Anti-Bacterial Agents : CK(4480) : AC(2136)

The present findings reveal the potential of ECG and kuraridin combination as a non-toxic herbal and antibiotics combination for MRSA treatment.

Article Published Date : Jan 07, 2023
Study Type : Animal Study
Additional Links
Substances : EGCG (Epigallocatechin gallate) : CK(1634) : AC(840), Flavonoids : CK(5388) : AC(2567), Sophora Flavescens : CK(162) : AC(76)
Diseases : Staphylococcus aureus: Methicillin-resistant (MRSA) : CK(498) : AC(279)
Pharmacological Actions : Anti-Inflammatory Agents : CK(43242) : AC(17300), Antimicrobial : CK(1665) : AC(835), Interleukin-1 beta downregulation : CK(6672) : AC(3233), Interleukin-6 Downregulation : CK(10137) : AC(3937), Tumor Necrosis Factor (TNF) Alpha Inhibitor : CK(12620) : AC(5195)

Discovery of kuraridin as a potential natural anti-melanogenic agent.

Article Published Date : Oct 17, 2024
Study Type : In Vitro Study
Additional Links
Substances : Flavonoids : CK(5388) : AC(2567), Sophora Flavescens : CK(162) : AC(76)
Diseases : Hyperpigmentation : CK(88) : AC(35)
Pharmacological Actions : Tyrosinase Inhibition : CK(7) : AC(5)

Anti-tumorigenic activity of sophoflavescenol against Lewis lung carcinoma in vitro and in vivo.

Article Published Date : Nov 30, 2011
Study Type : In Vitro Study
Additional Links
Substances : Flavonoids : CK(5381) : AC(2565), Sophora Flavescens : CK(161) : AC(75)
Diseases : Lung Cancer : CK(3213) : AC(1519)
Pharmacological Actions : Antioxidants : CK(37156) : AC(15599), Apoptotic : CK(10281) : AC(7960)
Additional Keywords : Plant Extracts : CK(19596) : AC(7175)

In vitro anti-Inflammatory and anti-oxidative stress activities of kushenol C isolated from the roots of Sophora flavescens.

Article Published Date : Apr 11, 2020
Study Type : In Vitro Study
Additional Links
Substances : Flavonoids : CK(5388) : AC(2567), Sophora Flavescens : CK(162) : AC(76)
Diseases : Lipopolysaccharide-Induced Toxicity : CK(3501) : AC(2042), Oxidative Stress : CK(16277) : AC(6418)
Pharmacological Actions : Anti-Inflammatory Agents : CK(43242) : AC(17300), Antioxidants : CK(37158) : AC(15601), Heme oxygenase-1 up-regulation : CK(1465) : AC(853), Nrf2 activation : CK(3424) : AC(1955), Superoxide Dismutase Up-regulation : CK(2590) : AC(1004)
Additional Keywords : Plant Extracts : CK(19596) : AC(7176)

Antibacterial and anti-biofilm activity of kushenol N against methicillin-resistant Staphylococcus aureus.

Article Published Date : Nov 18, 2025
Study Type : Animal Study
Additional Links
Substances : Flavonoids : CK(5381) : AC(2563), Sophora Flavescens : CK(158) : AC(73)
Diseases : Staphylococcus aureus: Methicillin-resistant (MRSA) : CK(496) : AC(278)
Pharmacological Actions : Anti-Bacterial Agents : CK(4478) : AC(2135)
Additional Keywords : Bacterial Infections: Resistance/Biofilm Formation

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