After much research to removing scroll lag from our app, I discovered that elements with the .sr-only class cause repaints when scrolling in overflowing divs.
Browser: Chrome
Operating System: Mac OSX Sierra
Please see the reduced test case here:
https://codepen.io/bbthorntz/pen/pdxLzd
In Chrome, with 'Inspector -> Rendering -> Paint Flashing' enabled, you can see that the presence of the element with the .sr-only class causes paint flashing. If you remove this element, the paint flashing stops.
Removing the clip-path property from the class appears to fix the issue.
I have yet to test whether this affects other browsers/operating systems.