I've been thinking about what it might look like to allow command-line arguments to be used to define any of the configuration options in datasette.yml, as alternative and more convenient syntax.

Here's what I've come up with:

datasette \
  -s settings.sql_time_limit_ms 1000 \
  -s plugins.datasette-auth-tokens.manage_tokens true \
  -s plugins.datasette-auth-tokens.manage_tokens_database tokens \
 mydatabase.db tokens.db

Which would be equivalent to datasette.yml containing this:

plugins:
  datasette-auth-tokens:
    manage_tokens: true
    manage_tokens_database: tokens
settings:
  sql_time_limit_ms: 1000

More details in #2143 (comment)