"Find the right clinical trial, explained simply."

TrialMatch AI is a patient-centered platform designed to bridge the gap between complex clinical trial data and patients seeking life-saving treatments. Using Google Gemini 3.1 and the official ClinicalTrials.gov API, we provide a personalized matching experience with plain-language explanations.

Watch the full guide and preview of the application here: TrialMatch AI Demo

• Smart Patient Intake: A guided medical form that captures the essential nuances of a patient's profile.
• AI-Powered Eligibility Analysis: Uses Gemini to analyze dense inclusion/exclusion criteria against the patient's medical history.
• Plain-Language Summaries: Translates medical jargon into easy-to-understand explanations.
• Match Scoring: Hybrid ranking system considering condition relevance, phase, and eligibility fit.
• Doctor Discussion Guide: AI-generated checklists to help patients talk to their healthcare providers about potential trials.

• Frontend: React, TypeScript, Tailwind CSS, shadcn/ui, Framer Motion.
• Backend: Node.js, Express, tsx.
• AI: Google Gemini 3.1 (via @google/genai).
• Data Source: ClinicalTrials.gov API v2.

1. Clone the repository.
2. Install dependencies: npm install.
3. Set up your environment variables (see .env.example).
4. Run the development server: npm run dev.

TrialMatch AI is an informational tool. It does not provide medical advice or determine final eligibility. All users are strictly advised to consult with their medical professionals.