Consider the following code, which generates some random exception, which is then rethrown as a custom attrs exception class (in this case suppressing the context using PEP 409's from None):

import attr

@attr.s(frozen=True, slots=True, auto_exc=True)
class MyException(BaseException):
    msg:str = attr.ib()

try:
    next(iter([]))
except StopIteration:
    raise MyException("test") from None

In CPython, this works as expected:

Traceback (most recent call last):
  File "scratch.py", line 10, in <module>
    raise MyException("test") from None
__main__.MyException: test

On PyPy, this yields a very weird, different exception:

Traceback (most recent call last):
  File "scratch.py", line 8, in <module>
    next(iter([]))
StopIteration

During handling of the above exception, another exception occurred:

Traceback (most recent call last):
  File "scratch.py", line 10, in <module>
    raise MyException("test") from None
  File ".venv-pypy3/site-packages/attr/_make.py", line 528, in _frozen_setattrs
    raise FrozenInstanceError()
attr.exceptions.FrozenInstanceError

I assume this is related to how __context__ and __cause__ are set when (re-)raising exceptions (see also the linked PEP for some info on that). The PEP says "To support raise Exception from None, __context__ will stay as it is, but __cause__ will start out as Ellipsis and will change to None when the raise Exception from None method is used.", so it's weird that only PyPy seems to be wrong here (which is also the reason I'm reporting this against attrs and not PyPy). Maybe CPython doesn't completely adhere to that and doesn't change the value in this case - or changes it bypassing the high-level __setattr__ API. Note that leaving the from None out doesn't change the weird behaviour. Maybe the __setattr__ frozen check should be skipped for __context__ and __cause__ of exceptions?

The versions of the interpreters I'm using are:

$ pypy3 -V
Python 3.6.9 (78d4c48fa091, Apr 30 2020, 07:55:31)
[PyPy 7.3.1 with GCC 10.0.1 20200328 (Red Hat 10.0.1-0.11)]
$ python3.9 -VV
Python 3.9.0 (default, Oct  6 2020, 00:00:00) 
[GCC 10.2.1 20200723 (Red Hat 10.2.1-1)]