More of an FYI than anything else -- PyQt5 appears not to work on Big Sur. I've tried 5.12 and 5.15.1, and both basically hang as soon as you make a mayavi, PyVista, or matplotlib Qt5Agg window.

So those thinking about upgrading, don't do so if you want to be able to use Python. For matplotlib at least we can use the MacOSX backend in the meantime, but 3D plotting is now (hopefully temporarily) totally broken for people who have upgraded. :(

Or maybe I'm the only one with this issue. If someone else upgrades, feel free to try it out and let me know!