Using Chrome 69 in win10, TM 4.8.5850 beta, and only GitHub News Feed Filter 8.2.4.

The issue is that some times when navigating to https://github.com/ from other GitHub pages the script doesn't work: in such cases I have to press Ctrl+F5 in order to work (plain F5 doesn't help).

STR

• Open https://github.com/ in a new tab: notice that the script works ok,
• Now click the "Explore" link (https://github.com/explore)
• Now click the Github logo icon to the upper left corner to navigate back to https://github.com/ :
  notice that the script doesn't work (there's no error in Console). Pressing Ctrl+F5 fixes the issue.

FWIW I've tried adding // @include https://github.com/* but unfortunately it didn't help.