In Expert Review: GridSync, a secure cloud app built on Tahoe-LAFS, @gusandrews wrote:

This warning alarmed one reviewer. And it is not just likely to worry users. The need to find and change security preferences adds a few more steps to setup, each one making it more likely users will abandon the software. Mac OS does not automatically open its “Security and Privacy” control panel — where users could get past the pop-up above — after displaying this dialog, meaning that it is likely most users will believe the dialog means they will not be able to open Gridsync at all.

RECOMMEND: This would be ranked “high” if we didn’t expect that the developer would eventually register the software. The developer should register this software with Apple before public release.