This refers to https://github.com/gorhill/uBlock/wiki/Privacy-stuff#command-line-switches

1. One of those first two switches seem to disable Chrome's ability to update extensions. Reinstalling from the Web Store is the only option to get new versions.
2. Switch worth adding (some can also be found in chrome://flags):

--disable-webgl
"Disable experimental WebGL support."
WebGL is a potential privacy and security risk.

Maybe worth adding:

--incognito
"Causes the browser to launch directly in incognito mode."

--no-referrers
"Don't send HTTP-Referer headers."
Breaks websites. Better:

--reduced-referrer-granularity
"Reduce the default referer header's granularity."
Example: Search for "What is my Referer" on search.disconnect.me and click a website which uses TLS. Without reduced referrer granularity it will show the whole URL, with it only the domain name will show.