We have a list of recommended cluster settings: https://cockroachlabs.atlassian.net/wiki/spaces/TS/pages/1359184360/Troubleshooting+CDC+runbook#What-are-general-best-practice-cluster-settings%3F

These settings should be the default value. The only one that is not for 22.1 is: kv.rangefeed.separated_intent_scan.enabled, which should be default set to true

Epic CRDB-11551