Originally reported at bytecodealliance/wasmtime-py#36 I'm able to reproduce this pretty easily with just this wasm file. Downloading that locally I can reproduce on Windows with:

$ gunzip yosys.wasm.gz
$ cargo run --release -- run yosys.wasm -- -V
...
    Finished release [optimized] target(s) in 3.84s
     Running `target\release\wasmtime.exe run yosys.wasm -- -V`
error: process didn't exit successfully: `target\release\wasmtime.exe run yosys.wasm -- -V` (exit code: 0xc0000028)

Something funny is going on here though because --opt-level 0 does not reproduce the issue (--opt-level 1 does though).

I'm trying to run this right now through wasm-reduce from Binaryen but so far it's only shaved off 3MB, which isn't a whole lot given the size of this binary...

@peterhuene I'm having trouble just opening things up in a debugger, would you be able to help look into this?