If a layout has a large number of buildings (~250), trying to do /callvote map map layout, /map map layout or /devmap map layout results in the game going back to the main menu. The log shows a warning "Warn: CL_ParseGamestate: bad command byte", used to be a warning about there being too many entities for the VM in one of the previous versions.
However, using /callvote layout layout after the map was already loaded results in the same layout loading normally.
An example layout showing this behaviour attached for map spacetracks.
humanpve1.zip